Epigenetics and Gene Expression

Institution: Centro Andaluz de Biología Molecular y Medicina Regenerativa (CABIMER)

Members (researchers): Jose C Reyes, Álvaro Gallego Martínez

Home page: https://www.cabimer.es/en/research-groups/epigenetics-and-gene-expression/
Contact email: jose.reyes@cabimer.es

Tools: CODfinder

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Research topics:

3D chromatin structure, Artificial Intelligence, Bayesian statistics, Chromatin accessibility, Data Visualization, Deep Learning in Biology, DNA methylation, Epigenomics, Experimental design, Expression Profiling, Frequentist analysis, Function prediction, Functional annotation, Functional genomics, Genome Assembly, Genome Sequencing, Genomic Annotation, Genomics, Histone structure and regulation, Integrative Analysis, Knowledge graphs, Large language models, Machine Learning in Biology, Mapping, Molecular flexibility, Molecular Interactions/Docking, Multivariate statistics, Mutation Analysis and design, Network Biology, Non-parametric statistics, Omics, Pathway analysis, Pathway analysis, Phylogenetic Analysis, Protein/Nucleic Acid design, Regulatory biology, RNA Sequencing (RNA-seq), Sequence Alignment, Sequence analysis, Sequence error correction, Single-cell (scRNA-seq), Single-cell omics, Spatial transcriptomics, Statistical Methods for Biology, Structure prediction, Structure-function relationship, Systems Biology, Transcriptomics, Variant calling

Publications

Peña-Gómez, M. J., Rodríguez-Martín, Y., del Rio Oliva, M., Wijesekara Hanthi, Y., Berrada, S., Freire, R., Masson, J. Y., Reyes, J. C., Costanzo, V., & Rosado, I. V. (2025). HMCES corrupts replication fork stability during base excision repair in homologous recombination–deficient cells. Science Advances, 11(13). https://doi.org/10.1126/sciadv.ads3227

Lamolda, M., Frejo, L., Martin-Lagos, J., Cara, F. E., Gallego-Martinez, A., & Lopez-Escamez, J. A. (2025). A Neuron-Like Cellular Model for Severe Tinnitus Associated with Rare Variations in the ANK2 Gene. Molecular Neurobiology, 62(5), 6467–6477. https://doi.org/10.1007/s12035-024-04674-8

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