Research line

Microbial metabolism operates and evolves under the trade-off between two principles: optimality under one given condition and minimal adjustment between conditions. These principles give rise to a three-dimensional space characterised by competing objectives: growth, robustness, and adaptability. At our lab, we are dedicated to deciphering the intricate relationship between metabolic robustness, adaptability, and optimality in microbial metabolism. We seek to investigate the mechanisms underlying metabolic cycles that promote high robustness in bacteria and explore how metabolic heterogeneity contributes to microbial survival in the face of perturbations. By gaining a deeper understanding of these fundamental aspects, we aim to apply this knowledge to diverse fields such as biotechnology and clinical microbiology. Our ultimate goal is to leverage this newfound understanding to develop innovative solutions for a wide range of applications.