System level analysis and designing microbial communities
The division of labor allows an expanded complexity and functionality in microorganisms. Guided by these interesting features, our research focuses on two key objectives. Firstly, we aim to unravel the mechanisms underlying the emergence of complex capabilities within microbial populations and communities. By studying how microorganisms interact and coordinate their activities, we seek to understand the factors that contribute to their expanded functionality. Secondly, we strive to harness and engineer this supracellular-level functionality for various biotechnological and clinical applications. To achieve this, we have developed a comprehensive suite of systems biology tools and evolutionary engineering frameworks. Our research finds practical application in multiple areas. For instance, we are working towards the valorization of complex polymers like lignin and plastic wastes, aiming to develop sustainable strategies for their use. Additionally, we focus on cost-effective production of plant-based secondary metabolites and the development of animal-free, sustainable ingredients for the food, beverage and nutraceutical industries.
Members (researchers): Juan Nogales Enrique
Research Groups: Systems Biotechnology Group

