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Institution: IATS
Research Groups: Fish pathology
Position: CT
Home page: https://scholar.google.com/citations?user=JPVGMccAAAAJ&hl=es
Contact email: alberto.falco@csic.es
BCB Committee: No committees assigned.
BCB Community: No communities assigned.
BCB Tools: No tools assigned.
BCB Services: No services assigned.
Research topics: Animal genomics, Microbial Communities, Gene regulatory networks, Phylogenetic Analysis
Biography: After graduating in Biological Sciences at the University of Alicante (2002, 8.72), I was granted a predoctoral fellowship (FPU program, MECD) for my Ph.D. studies at the Miguel Hernández University (UMH) (2008, cum laude). These studies focused on the description of the antiviral activity in fish of defensins, a family of antimicrobial peptides (AMPs). The obtained results were published in 2 book chapters, 2 review articles, and 5 scientific articles, one of which reports the antiviral activity of fish defensins for the first time, being also pioneering in their discovery.
I then moved to the industrial sector (an SME called "CGB-Edson") for 1.5 years and from this work, 2 research articles and 1 book chapter were published on the development of targeted immunoliposomes loaded with AMPs (melittin) for antitumor and antiviral applications. Later, I was appointed to a postdoctoral position (UMH) within a large national consortium supported by an Ingenio Consolider project ("Aquagenomics") on the implementation of biotechnological tools for aquaculture. Based on my work, 8 articles were published, as well as 1 book chapter that was selected by the publisher to be reedited as an independent book.
In 2009, I started a 4-year international stage funded by the European Commission. First, I held a 2-year postdoctoral position at Keele University (UK) within a Marie Curie - International Training Network (MC-ITN) project. Subsequently, I was awarded a Marie Curie Intra- European Fellowship (MC-IEF) to work at Wageningen University (Holland) for another 2 years. During these periods, I studied the immunomodulation and acute phase responses mediated by chitosan when orally administered in supplemented fish feeds (ITN), and the interferon response (IEF), using carp as biological model in both cases. This experience allowed me to build a large network of international collaborators (7 articles) and to strengthen my national network (1 article). It is remarkable my role as speaker, organizer and chairman of a large workshop at the 15th Conference of the European Association of Fish Pathologists (EAFP). This also facilitated a contract with Hipra Ltd. to co-lead a research project for 2 years at the UMH. Based on the results of this industrial collaboration, a new product to improve fish health was commercialized (rights retained by the company) and a paper was published.
From 2016, I led a small research group at UMH. During this phase, I was awarded a 3-year JIN national project as PI (RTI2018-101969-J-I00, MICIU, Retos, 2019-2022), and then I was a key participant in the application of a funded 2-year national project (Metdisfish, MAPA & EMFAF, 2022-2023), coordinated between UMH and IIM-CSIC. Recently, Dec 2023, I was appointed to a permanent position as Tenured Scientist at the Institute of Aquaculture “Torre de la Sal” (IATS-CSIC) to build a research group, being the main objective of my research lines tackling (mostly viral) infectious diseases by sustainable approaches in order to alleviate the negative impact from current procedures in intensive animal production on both wild ecosystems and human and animal health (i.e., the release of large amounts of pathogens from farm outbreaks, the continuously-growing antibiotic pollution and the consequent selection of multi-drug resistance microorganisms). Within this framework, my research interests encompass the i) the identification of innate immune molecules, metabolites and extracts from aquatic organisms with antimicrobial and/or immunomodulatory properties, ii) the assessment of the most efficient ways of administration, with special interest in oral treatments such as feed supplements (or functional diets) for mass supply, and iii) the development of biocompatible and biodegradable polymer nanomaterials to protect (if necessary) the loaded drugs from degradation in the supply formulations.
In summary, I have participated in 4 local/regional/institutional (3 as PI), 10 national (2 as PI) and 2 international competitive projects with different roles. My publication record (all peer-reviewed) includes 56 publications indexed by JCR (cumulative IF of 237), of which 42 (75%) are Q1-positioned (the rest in Q2), I am key author (1st, last or corresponding) in 27 (48%), and 20 (36%) include international collaborators. In addition, 1 of my publications was awarded with the VIII national prize "Jacumar". In total, my work has been cited 3,406 times and my h-index reaches a value of 25 (Scopus, Jul. 2025). I have also published 4 book chapters, 1 book and 2 divulgative articles (5 of them as 1st author). In addition, I have contributed 83 communications to a total of 19 national and 26 international congresses. Regarding teaching, I have co-supervised 3 Ph.D. theses (all cum laude, 1 with honors) and all students have continued their scientific careers in either the public or the private sector. I have also supervised 10 master's (average grade above 9/10) and 13 undergraduate theses (9/10). I have also participated in the teaching program (undergraduate and master's) at UMH, including the university courses "Introduction to Nanobiotechnology", which I created and coordinate, and "Advances in Virology Research". Finally, it is worth mentioning that I am a regular reviewer of several Q1 journals, guest editor of several special issues, evaluator of the "Agencia Estatal de Investigación" (AEI) since 2019, among other State Agencies, and recently co-organized the XI Congress of Young Researchers in Polymers (JIP2023).
Publications
Díaz-Puertas, R., Álvarez-Martínez, F. J., Rodríguez-Cañas, E., Borrás, F., Valente, A. J. M., Paixao, J. A., Falcó, A., & Mallavia, R. (2025). An Innovative Approach Based on the Green Synthesis of Silver Nanoparticles Using Pomegranate Peel Extract for Antibacterial Purposes. Bioinorganic Chemistry and Applications, 2025(1). Portico. https://doi.org/10.1155/bca/2009069
Adamek, M., Matras, M., Surachetpong, W., Rakus, K., Stachnik, M., Bauer, J., Falco, A., Jung-Schroers, V., Piewbang, C., Techangamsuwan, S., El Rahman, S. A., Paley, R., Reichert, M., & Steinhagen, D. (2023). How susceptible are rainbow trout and brown trout to infection with tilapia lake virus at increased water temperature – Is there any potential for climate change driven host jump? Aquaculture, 571, 739469. https://doi.org/10.1016/j.aquaculture.2023.739469
Díaz-Puertas, R., Álvarez-Martínez, F. J., Falco, A., Barrajón-Catalán, E., & Mallavia, R. (2023). Phytochemical-Based Nanomaterials against Antibiotic-Resistant Bacteria: An Updated Review. Polymers, 15(6), 1392. https://doi.org/10.3390/polym15061392
Díaz-Puertas, R., Rodríguez-Cañas, E., Bello-Perez, M., Fernández-Oliver, M., Mallavia, R., & Falco, A. (2023). Viricidal Activity of Thermoplastic Polyurethane Materials with Silver Nanoparticles. Nanomaterials, 13(9), 1467. https://doi.org/10.3390/nano13091467
Díaz-Puertas, R., Adamek, M., Mallavia, R., & Falco, A. (2023). Fish Skin Mucus Extracts: An Underexplored Source of Antimicrobial Agents. Marine Drugs, 21(6), 350. https://doi.org/10.3390/md21060350
Adamek, M., Rebl, A., Matras, M., Lodder, C., Abd El Rahman, S., Stachnik, M., Rakus, K., Bauer, J., Falco, A., Jung-Schroers, V., Piewbang, C., Techangamsuwan, S., Surachetpong, W., Reichert, M., Tetens, J., & Steinhagen, D. (2022). Immunological insights into the resistance of Nile tilapia strains to an infection with tilapia lake virus. Fish & Shellfish Immunology, 124, 118–133. https://doi.org/10.1016/j.fsi.2022.03.027
Adamek, M., Matras, M., Rebl, A., Stachnik, M., Falco, A., Bauer, J., Miebach, A.-C., Teitge, F., Jung-Schroers, V., Abdullah, M., Krebs, T., Schröder, L., Fuchs, W., Reichert, M., & Steinhagen, D. (2022). Don’t Let It Get Under Your Skin! – Vaccination Protects the Skin Barrier of Common Carp From Disruption Caused by Cyprinid Herpesvirus 3. Frontiers in Immunology, 13. https://doi.org/10.3389/fimmu.2022.787021
Falco, A., Adamek, M., Pereiro, P., Hoole, D., Encinar, J., Novoa, B., & Mallavia, R. (2022). The Immune System of Marine Organisms as Source for Drugs against Infectious Diseases. Marine Drugs, 20(6), 363. https://doi.org/10.3390/md20060363
Bello-Perez, M., Esparza, I., De la Encina, A., Bartolome, T., Molina, T., Sanjuan, E., Falco, A., Enjuanes, L., Sola, I., & Usera, F. (2022). Pulsed-Xenon Ultraviolet Light Highly Inactivates Human Coronaviruses on Solid Surfaces, Particularly SARS-CoV-2. International Journal of Environmental Research and Public Health, 19(21), 13780. https://doi.org/10.3390/ijerph192113780
Klionsky, D. J., Abdel-Aziz, A. K., Abdelfatah, S., Abdellatif, M., Abdoli, A., Abel, S., Abeliovich, H., Abildgaard, M. H., Abudu, Y. P., Acevedo-Arozena, A., Adamopoulos, I. E., Adeli, K., Adolph, T. E., Adornetto, A., Aflaki, E., Agam, G., Agarwal, A., Aggarwal, B. B., Agnello, M., … Tong, C.-K. (2021). Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1. Autophagy, 17(1), 1–382. https://doi.org/10.1080/15548627.2020.1797280
Neira, J. L., Palomino-Schätzlein, M., Hurtado-Gómez, E., Ortore, M. G., & Falcó, A. (2021). An N-terminal half fragment of the histidine phosphocarrier protein, HPr, is disordered but binds to HPr partners and shows antibacterial properties. Biochimica et Biophysica Acta (BBA) - General Subjects, 1865(12), 130015. https://doi.org/10.1016/j.bbagen.2021.130015
Bello-Perez, M., Adamek, M., Coll, J., Figueras, A., Novoa, B., & Falco, A. (2021). Modulation of the Tissue Expression Pattern of Zebrafish CRP-Like Molecules Suggests a Relevant Antiviral Role in Fish Skin. Biology, 10(2), 78. https://doi.org/10.3390/biology10020078
Neira, J. L., Ortega-Alarcón, D., Rizzuti, B., Palomino-Schätzlein, M., Velázquez-Campoy, A., & Falcó, A. (2021). Residual Helicity at the Active Site of the Histidine Phosphocarrier, HPr, Modulates Binding Affinity to Its Natural Partners. International Journal of Molecular Sciences, 22(19), 10805. https://doi.org/10.3390/ijms221910805
Mira, A., Rubio-Camacho, M., Alarcón, D., Rodríguez-Cañas, E., Fernández-Carvajal, A., Falco, A., & Mallavia, R. (2021). L-Menthol-Loadable Electrospun Fibers of PMVEMA Anhydride for Topical Administration. Pharmaceutics, 13(11), 1845. https://doi.org/10.3390/pharmaceutics13111845
Falco, A., Bello-Perez, M., Díaz-Puertas, R., Mold, M., & Adamek, M. (2021). Update on the Inactivation Procedures for the Vaccine Development Prospects of a New Highly Virulent RGNNV Isolate. Vaccines, 9(12), 1441. https://doi.org/10.3390/vaccines9121441
Bello-Perez, M., Pereiro, P., Coll, J., Novoa, B., Perez, L., & Falco, A. (2020). Zebrafish C-reactive protein isoforms inhibit SVCV replication by blocking autophagy through interactions with cell membrane cholesterol. Scientific Reports, 10(1). https://doi.org/10.1038/s41598-020-57501-0
Mira, A., Sainz-Urruela, C., Codina, H., Jenkins, S. I., Rodriguez-Diaz, J. C., Mallavia, R., & Falco, A. (2020). Physico-Chemically Distinct Nanomaterials Synthesized from Derivates of a Poly(Anhydride) Diversify the Spectrum of Loadable Antibiotics. Nanomaterials, 10(3), 486. https://doi.org/10.3390/nano10030486
Bello-Perez, M., Sola, I., Novoa, B., Klionsky, D. J., & Falco, A. (2020). Canonical and Noncanonical Autophagy as Potential Targets for COVID-19. Cells, 9(7), 1619. https://doi.org/10.3390/cells9071619
Falco, A., & Mallavia, R. (2020). Electrospun Nanomaterials: Applications in Food, Environmental Remediation, and Bioengineering. Nanomaterials, 10(9), 1714. https://doi.org/10.3390/nano10091714
Bello-Perez, M., Falco, A., Novoa, B., Perez, L., & Coll, J. (2019). Hydroxycholesterol binds and enhances the anti-viral activities of zebrafish monomeric c-reactive protein isoforms. PLOS ONE, 14(1), e0201509. https://doi.org/10.1371/journal.pone.0201509
Martínez-Ortega, L., Mira, A., Fernandez-Carvajal, A., Mateo, C. R., Mallavia, R., & Falco, A. (2019). Development of A New Delivery System Based on Drug-Loadable Electrospun Nanofibers for Psoriasis Treatment. Pharmaceutics, 11(1), 14. https://doi.org/10.3390/pharmaceutics11010014
Falco, A., Medina-Gali, R. M., Poveda, J. A., Bello-Perez, M., Novoa, B., & Encinar, J. A. (2019). Antiviral Activity of a Turbot (Scophthalmus maximus) NK-Lysin Peptide by Inhibition of Low-pH Virus-Induced Membrane Fusion. Marine Drugs, 17(2), 87. https://doi.org/10.3390/md17020087
Medina-Gali, R., Belló-Pérez, M., Martínez-López, A., Falcó, A., Ortega-Villaizan, M. M., Encinar, J. A., Novoa, B., Coll, J., & Perez, L. (2018). Chromatin immunoprecipitation and high throughput sequencing of SVCV-infected zebrafish reveals novel epigenetic histone methylation patterns involved in antiviral immune response. Fish & Shellfish Immunology, 82, 514–521. https://doi.org/10.1016/j.fsi.2018.08.056
Bello-Perez, M., Falco, A., Encinar, J. A., Novoa, B., Perez, L., & Coll, J. (2018). 25-Hydroxyl-cholesterol Binds and Enhance Anti-viral Effects of Zebrafish Monomeric C-reactive Proteins. https://doi.org/10.1101/371856
Vázquez-Guilló, R., Falco, A., Martínez-Tomé, M. J., Mateo, C. R., Herrero, M. A., Vázquez, E., & Mallavia, R. (2018). Advantageous Microwave-Assisted Suzuki Polycondensation for the Synthesis of Aniline-Fluorene Alternate Copolymers as Molecular Model with Solvent Sensing Properties. Polymers, 10(2), 215. https://doi.org/10.3390/polym10020215
Bello-Pérez, M., Falco, A., Galiano, V., Coll, J., Perez, L., & Encinar, J. A. (2018). Discovery of nonnucleoside inhibitors of polymerase from infectious pancreatic necrosis virus (IPNV). Drug Design, Development and Therapy, Volume 12, 2337–2359. https://doi.org/10.2147/dddt.s171087
Vázquez-Guilló, R., Martínez-Tomé, M. J., Kahveci, Z., Torres, I., Falco, A., Mallavia, R., & Mateo, C. R. (2018). Synthesis and Characterization of a Novel Green Cationic Polyfluorene and Its Potential Use as a Fluorescent Membrane Probe. Polymers, 10(9), 938. https://doi.org/10.3390/polym10090938
Bello-Perez, M., Falco, A., Medina, R., Encinar, J. A., Novoa, B., Perez, L., Estepa, A., & Coll, J. (2017). Structure and functionalities of the human c-reactive protein compared to the zebrafish multigene family of c-reactive-like proteins. Developmental & Comparative Immunology, 69, 33–40. https://doi.org/10.1016/j.dci.2016.12.001
Bello-Perez, M., Falco, A., Medina-Gali, R., Pereiro, P., Encinar, J. A., Novoa, B., Perez, L., & Coll, J. (2017). Neutralization of viral infectivity by zebrafish c-reactive protein isoforms. Molecular Immunology, 91, 145–155. https://doi.org/10.1016/j.molimm.2017.09.005
Mira, A., Mateo, C. R., Mallavia, R., & Falco, A. (2017). Poly(methyl vinyl ether-alt-maleic acid) and ethyl monoester as building polymers for drug-loadable electrospun nanofibers. Scientific Reports, 7(1). https://doi.org/10.1038/s41598-017-17542-4
Espín-Palazón, R., Martínez-López, A., Roca, F. J., López-Muñoz, A., Tyrkalska, S. D., Candel, S., García-Moreno, D., Falco, A., Meseguer, J., Estepa, A., & Mulero, V. (2016). TNFα Impairs Rhabdoviral Clearance by Inhibiting the Host Autophagic Antiviral Response. PLOS Pathogens, 12(6), e1005699. https://doi.org/10.1371/journal.ppat.1005699
Kahveci, Z., Vázquez-Guilló, R., Mira, A., Martinez, L., Falcó, A., Mallavia, R., & Mateo, C. R. (2016). Selective recognition and imaging of bacterial model membranes over mammalian ones by using cationic conjugated polyelectrolytes. The Analyst, 141(22), 6287–6296. https://doi.org/10.1039/c6an01427e
Falco, A., Miest, J. J., Pionnier, N., Pietretti, D., Forlenza, M., Wiegertjes, G. F., & Hoole, D. (2014). β-Glucan-supplemented diets increase poly(I:C)-induced gene expression of Mx, possibly via Tlr3-mediated recognition mechanism in common carp (Cyprinus carpio). Fish & Shellfish Immunology, 36(2), 494–502. https://doi.org/10.1016/j.fsi.2013.12.005
Pionnier, N., Falco, A., Miest, J. J., Shrive, A. K., & Hoole, D. (2014). Feeding common carp Cyprinus carpio with β-glucan supplemented diet stimulates C-reactive protein and complement immune acute phase responses following PAMPs injection. Fish & Shellfish Immunology, 39(2), 285–295. https://doi.org/10.1016/j.fsi.2014.05.008
Falco, A., Barrajón-Catalán, E., Menéndez-Gutiérrez, M. P., Coll, J., Micol, V., & Estepa, A. (2013). Melittin-loaded immunoliposomes against viral surface proteins, a new approach to antiviral therapy. Antiviral Research, 97(2), 218–221. https://doi.org/10.1016/j.antiviral.2012.12.004
Chinchilla, B., Gomez-Casado, E., Encinas, P., Falco, A., Estepa, A., & Coll, J. (2013). In VitroNeutralization of Viral Hemorrhagic Septicemia Virus by Plasma from Immunized Zebrafish. Zebrafish, 10(1), 43–51. https://doi.org/10.1089/zeb.2012.0805
Pionnier, N., Falco, A., Miest, J., Frost, P., Irnazarow, I., Shrive, A., & Hoole, D. (2013). Dietary β-glucan stimulate complement and C-reactive protein acute phase responses in common carp (Cyprinus carpio) during an Aeromonas salmonicida infection. Fish & Shellfish Immunology, 34(3), 819–831. https://doi.org/10.1016/j.fsi.2012.12.017
Pietretti, D., Spaink, H. P., Falco, A., Forlenza, M., & Wiegertjes, G. F. (2013). Accessory molecules for Toll-like receptors in Teleost fish. Identification of TLR4 interactor with leucine-rich repeats (TRIL). Molecular Immunology, 56(4), 745–756. https://doi.org/10.1016/j.molimm.2013.07.012
Miest, J. J., Falco, A., Pionnier, N. P. M., Frost, P., Irnazarow, I., Williams, G. T., & Hoole, D. (2012). The influence of dietary β-glucan, PAMP exposure and Aeromonas salmonicida on apoptosis modulation in common carp (Cyprinus carpio). Fish & Shellfish Immunology, 33(4), 846–856. https://doi.org/10.1016/j.fsi.2012.07.014
Falco, A., Frost, P., Miest, J., Pionnier, N., Irnazarow, I., & Hoole, D. (2012). Reduced inflammatory response to Aeromonas salmonicida infection in common carp (Cyprinus carpio L.) fed with β-glucan supplements. Fish & Shellfish Immunology, 32(6), 1051–1057. https://doi.org/10.1016/j.fsi.2012.02.028
Pereiro, P., Martinez-Lopez, A., Falco, A., Dios, S., Figueras, A., Coll, J. M., Novoa, B., & Estepa, A. (2012). Protection and antibody response induced by intramuscular DNA vaccine encoding for viral haemorrhagic septicaemia virus (VHSV) G glycoprotein in turbot (Scophthalmus maximus). Fish & Shellfish Immunology, 32(6), 1088–1094. https://doi.org/10.1016/j.fsi.2012.03.004
Falco, A., Cartwright, J. R., Wiegertjes, G. F., & Hoole, D. (2012). Molecular characterization and expression analysis of two new C-reactive protein genes from common carp (Cyprinus carpio). Developmental & Comparative Immunology, 37(1), 127–138. https://doi.org/10.1016/j.dci.2011.10.005
Balseiro, P., Falcó, A., Romero, A., Dios, S., Martínez-López, A., Figueras, A., Estepa, A., & Novoa, B. (2011). Mytilus galloprovincialis Myticin C: A Chemotactic Molecule with Antiviral Activity and Immunoregulatory Properties. PLoS ONE, 6(8), e23140. https://doi.org/10.1371/journal.pone.0023140
Ortega-Villaizan, M., Chico, V., Martinez-Lopez, A., Falco, A., Perez, L., Coll, J. M., & Estepa, A. (2011). In vitro analysis of the factors contributing to the antiviral state induced by a plasmid encoding the viral haemorrhagic septicaemia virus glycoprotein G in transfected trout cells. Vaccine, 29(4), 737–743. https://doi.org/10.1016/j.vaccine.2010.11.021
García, I., Galiana, A., Falcó, A., Estepa, A., & Perez, L. (2011). Characterization of an infectious pancreatic necrosis (IPN) virus carrier cell culture with resistance to superinfection with heterologous viruses. Veterinary Microbiology, 149(1–2), 48–55. https://doi.org/10.1016/j.vetmic.2010.10.017
Barrajón-Catalán, E., Menéndez-Gutiérrez, M. P., Falco, A., Carrato, A., Saceda, M., & Micol, V. (2010). Selective death of human breast cancer cells by lytic immunoliposomes: Correlation with their HER2 expression level. Cancer Letters, 290(2), 192–203. https://doi.org/10.1016/j.canlet.2009.09.010
Chico, V., Martinez-Lopez, A., Ortega-Villaizan, M., Falco, A., Perez, L., Coll, J. M., & Estepa, A. (2010). Pepscan Mapping of Viral Hemorrhagic Septicemia Virus Glycoprotein G Major Lineal Determinants Implicated in Triggering Host Cell Antiviral Responses Mediated by Type I Interferon. Journal of Virology, 84(14), 7140–7150. https://doi.org/10.1128/jvi.00023-10
Falco, A., Encinas, P., Carbajosa, S., Cuesta, A., Chaves-Pozo, E., Tafalla, C., Estepa, A., & Coll, J. M. (2009). Transfection improvements of fish cell lines by using deacylated polyethylenimine of selected molecular weights. Fish & Shellfish Immunology, 26(3), 559–566. https://doi.org/10.1016/j.fsi.2009.02.013
Ortega-Villaizan, M., Chico, V., Falco, A., Perez, L., Coll, J. M., & Estepa, A. (2009). The rainbow trout TLR9 gene and its role in the immune responses elicited by a plasmid encoding the glycoprotein G of the viral haemorrhagic septicaemia rhabdovirus (VHSV). Molecular Immunology, 46(8–9), 1710–1717. https://doi.org/10.1016/j.molimm.2009.02.006
Chico, V., Ortega-Villaizan, M., Falco, A., Tafalla, C., Perez, L., Coll, J. M., & Estepa, A. (2009). The immunogenicity of viral haemorragic septicaemia rhabdovirus (VHSV) DNA vaccines can depend on plasmid regulatory sequences. Vaccine, 27(13), 1938–1948. https://doi.org/10.1016/j.vaccine.2009.01.103
Falco, A., Ortega-Villaizan, M., Chico, V., Brocal, I., Perez, L., Coll, J., & Estepa, A. (2009). Antimicrobial Peptides as Model Molecules for the Development of Novel Antiviral Agents in Aquaculture. Mini-Reviews in Medicinal Chemistry, 9(10), 1159–1164. https://doi.org/10.2174/138955709789055171
Falco, A., Brocal, I., Pérez, L., Coll, J. M., Estepa, A., & Tafalla, C. (2008). In vivo modulation of the rainbow trout (Oncorhynchus mykiss) immune response by the human alpha defensin 1, HNP1. Fish & Shellfish Immunology, 24(1), 102–112. https://doi.org/10.1016/j.fsi.2007.09.007
Falco, A., Chico, V., Marroquí, L., Perez, L., Coll, J. M., & Estepa, A. (2008). Expression and antiviral activity of a β-defensin-like peptide identified in the rainbow trout (Oncorhynchus mykiss) EST sequences. Molecular Immunology, 45(3), 757–765. https://doi.org/10.1016/j.molimm.2007.06.358
Falco, A., Mas, V., Tafalla, C., Perez, L., Coll, J. M., & Estepa, A. (2007). Dual antiviral activity of human alpha-defensin-1 against viral haemorrhagic septicaemia rhabdovirus (VHSV): Inactivation of virus particles and induction of a type I interferon-related response. Antiviral Research, 76(2), 111–123. https://doi.org/10.1016/j.antiviral.2007.06.006
Brocal, I., Falco, A., Mas, V., Rocha, A., Perez, L., Coll, J. M., & Estepa, A. (2006). Stable expression of bioactive recombinant pleurocidin in a fish cell line. Applied Microbiology and Biotechnology, 72(6), 1217–1228. https://doi.org/10.1007/s00253-006-0393-7
Mas, V., Falco, A., Brocal, I., Perez, L., Coll, J. M., & Estepa, A. (2006). Identification of selective inhibitors of VHSV from biased combinatorial libraries of N,N′-disubstituted 2,5-piperazinediones. Antiviral Research, 72(2), 107–115. https://doi.org/10.1016/j.antiviral.2006.04.005
Research lines:
There are no lines of investigation associated with this user.
Funding:
No funded projects.