Olivares, M., Hernández-Calderón, P., Cárdenas-Brito, S., Liébana-García, R., Sanz, Y., & Benítez-Páez, A. (2024). Gut microbiota DPP4-like enzymes are increased in type-2 diabetes and contribute to incretin inactivation. Genome Biology, 25(1). https://doi.org/10.1186/s13059-024-03325-4

Carpio, L. E., Olivares, M., Benítez-Paez, A., Serrano-Candelas, E., Barigye, S. J., Sanz, Y., & Gozalbes, R. (2024). Comparative Binding Study of Gliptins to Bacterial DPP4-like Enzymes for the Treatment of Type 2 Diabetes Mellitus (T2DM). International Journal of Molecular Sciences, 25(11), 5744. https://doi.org/10.3390/ijms25115744

Benítez-Páez, A. (2023). Editorial: Contribution of the maternal microbiome to offspring health. Frontiers in Nutrition, 10. https://doi.org/10.3389/fnut.2023.1229447

Hernández-Calderón, P., Wiedemann, L., & Benítez-Páez, A. (2022). The microbiota composition drives personalized nutrition: Gut microbes as predictive biomarkers for the success of weight loss diets. Frontiers in Nutrition, 9. https://doi.org/10.3389/fnut.2022.1006747

Hillestad, E. M. R., van der Meeren, A., Nagaraja, B. H., Bjørsvik, B. R., Haleem, N., Benitez-Paez, A., Sanz, Y., Hausken, T., Lied, G. A., Lundervold, A., & Berentsen, B. (2022). Gut bless you: The microbiota-gut-brain axis in irritable bowel syndrome. World Journal of Gastroenterology, 28(4), 412–431. https://doi.org/10.3748/wjg.v28.i4.412

Sánchez-Sánchez, P., Santonja, F. J., & Benítez-Páez, A. (2022). Assessment of human microbiota stability across longitudinal samples using iteratively growing-partitioned clustering. Briefings in Bioinformatics, 23(2). https://doi.org/10.1093/bib/bbac055

Caparrós, E., Cenit, M. C., Muriel, J., Benítez-Páez, A., Moreno, M. V., González-Delgado, P., Rubio, G., Sanz, Y., & Fernández, J. (2022). Intestinal microbiota is modified in pediatric food protein–induced enterocolitis syndrome. Journal of Allergy and Clinical Immunology: Global, 1(4), 217–224. https://doi.org/10.1016/j.jacig.2022.07.005

Benítez-Páez, A., Hartstra, A. V., Nieuwdorp, M., & Sanz, Y. (2022). Species- and strain-level assessment using rrn long-amplicons suggests donor’s influence on gut microbial transference via fecal transplants in metabolic syndrome subjects. Gut Microbes, 14(1). https://doi.org/10.1080/19490976.2022.2078621

López-Almela, I., Romaní-Pérez, M., Bullich-Vilarrubias, C., Benítez-Páez, A., Gómez Del Pulgar, E. M., Francés, R., Liebisch, G., & Sanz, Y. (2021). Bacteroides uniformis combined with fiber amplifies metabolic and immune benefits in obese mice. Gut Microbes, 13(1), 1–20. https://doi.org/10.1080/19490976.2020.1865706

Benítez‐Páez, A., Hess, A. L., Krautbauer, S., Liebisch, G., Christensen, L., Hjorth, M. F., Larsen, T. M., & Sanz, Y. (2021). Sex, Food, and the Gut Microbiota: Disparate Response to Caloric Restriction Diet with Fiber Supplementation in Women and Men. Molecular Nutrition & Food Research, 65(8). Portico. https://doi.org/10.1002/mnfr.202000996

Fabersani, E., Portune, K., Campillo, I., López-Almela, I., la Paz, S. M., Romaní-Pérez, M., Benítez-Páez, A., & Sanz, Y. (2021). Bacteroides uniformis CECT 7771 alleviates inflammation within the gut-adipose tissue axis involving TLR5 signaling in obese mice. Scientific Reports, 11(1). https://doi.org/10.1038/s41598-021-90888-y

Romaní‐Pérez, M., López‐Almela, I., Bullich‐Vilarrubias, C., Rueda‐Ruzafa, L., Gómez Del Pulgar, E. M., Benítez‐Páez, A., Liebisch, G., Lamas, J. A., & Sanz, Y. (2021). Holdemanella biformis improves glucose tolerance and regulates GLP‐1 signaling in obese mice. The FASEB Journal, 35(7). Portico. https://doi.org/10.1096/fj.202100126r

Turroni, S., & Benítez-Páez, A. (2021). Editorial: Remodeling Composition and Function of Microbiome by Dietary Strategies - Functional Foods Perspective. Frontiers in Nutrition, 8. https://doi.org/10.3389/fnut.2021.811102

Delzenne, N. M., Olivares, M., Neyrinck, A. M., Beaumont, M., Kjølbæk, L., Larsen, T. M., Benítez-Páez, A., Romaní-Pérez, M., Garcia-Campayo, V., Bosscher, D., Sanz, Y., & van der Kamp, J.-W. (2020). Nutritional interest of dietary fiber and prebiotics in obesity: Lessons from the MyNewGut consortium. Clinical Nutrition, 39(2), 414–424. https://doi.org/10.1016/j.clnu.2019.03.002

Kjølbæk, L., Benítez-Páez, A., Gómez del Pulgar, E. M., Brahe, L. K., Liebisch, G., Matysik, S., Rampelli, S., Vermeiren, J., Brigidi, P., Larsen, L. H., Astrup, A., & Sanz, Y. (2020). Arabinoxylan oligosaccharides and polyunsaturated fatty acid effects on gut microbiota and metabolic markers in overweight individuals with signs of metabolic syndrome: A randomized cross-over trial. Clinical Nutrition, 39(1), 67–79. https://doi.org/10.1016/j.clnu.2019.01.012

Gómez del Pulgar, E. M., Benítez-Páez, A., & Sanz, Y. (2020). Safety Assessment of Bacteroides Uniformis CECT 7771, a Symbiont of the Gut Microbiota in Infants. Nutrients, 12(2), 551. https://doi.org/10.3390/nu12020551

Benítez-Páez, A., Gómez del Pugar, E. M., López-Almela, I., Moya-Pérez, Á., Codoñer-Franch, P., & Sanz, Y. (2020). Depletion of Blautia Species in the Microbiota of Obese Children Relates to Intestinal Inflammation and Metabolic Phenotype Worsening. MSystems, 5(2). https://doi.org/10.1128/msystems.00857-19

Benítez-Páez, A., Olivares, M., Szajewska, H., Pieścik-Lech, M., Polanco, I., Castillejo, G., Nuñez, M., Ribes-Koninckx, C., Korponay-Szabó, I. R., Koletzko, S., Meijer, C. R., Mearin, M. L., & Sanz, Y. (2020). Breast-Milk Microbiota Linked to Celiac Disease Development in Children: A Pilot Study From the PreventCD Cohort. Frontiers in Microbiology, 11. https://doi.org/10.3389/fmicb.2020.01335

Berentsen, B., Nagaraja, B. H., Teige, E. P., Lied, G. A., Lundervold, A. J., Lundervold, K., Steinsvik, E. K., Hillestad, E. R., Valeur, J., Brønstad, I., Gilja, O. H., Osnes, B., Hatlebakk, J. G., Haász, J., Labus, J., Gupta, A., Mayer, E. A., Benitez-Páez, A., Sanz, Y., … Hausken, T. (2020). Study protocol of the Bergen brain-gut-microbiota-axis study. Medicine, 99(37), e21950. https://doi.org/10.1097/md.0000000000021950

Benítez-Páez, A., Hartstra, A. V., Nieuwdorp, M., & Sanz, Y. (2020). Species- and strain-level assessment usingrrnlong-amplicons suggests donor’s influence on gut microbial transference via fecal transplants in metabolic syndrome subjects. https://doi.org/10.1101/2020.09.11.292896

Christensen, L., Sørensen, C. V., Wøhlk, F. U., Kjølbæk, L., Astrup, A., Sanz, Y., Hjorth, M. F., & Benítez-Páez, A. (2020). Microbial enterotypes beyond genus level: Bacteroides species as a predictive biomarker for weight change upon controlled intervention with arabinoxylan oligosaccharides in overweight subjects. Gut Microbes, 12(1), 1847627. https://doi.org/10.1080/19490976.2020.1847627

Agudelo-Ochoa, G. M., Valdés-Duque, B. E., Giraldo-Giraldo, N. A., Jaillier-Ramírez, A. M., Giraldo-Villa, A., Acevedo-Castaño, I., Yepes-Molina, M. A., Barbosa-Barbosa, J., & Benítez-Paéz, A. (2020). Gut microbiota profiles in critically ill patients, potential biomarkers and risk variables for sepsis. Gut Microbes, 12(1), 1707610. https://doi.org/10.1080/19490976.2019.1707610

Hartstra, A. V., Schüppel, V., Imangaliyev, S., Schrantee, A., Prodan, A., Collard, D., Levin, E., Dallinga-Thie, G., Ackermans, M. T., Winkelmeijer, M., Havik, S. R., Metwaly, A., Lagkouvardos, I., Nier, A., Bergheim, I., Heikenwalder, M., Dunkel, A., Nederveen, A. J., Liebisch, G., … Nieuwdorp, M. (2020). Infusion of donor feces affects the gut–brain axis in humans with metabolic syndrome. Molecular Metabolism, 42, 101076. https://doi.org/10.1016/j.molmet.2020.101076

Alehosseini, A., Gomez del Pulgar, E.-M., Fabra, M. J., Gómez-Mascaraque, L. G., Benítez-Páez, A., Sarabi-Jamab, M., Ghorani, B., & Lopez-Rubio, A. (2019). Agarose-based freeze-dried capsules prepared by the oil-induced biphasic hydrogel particle formation approach for the protection of sensitive probiotic bacteria. Food Hydrocolloids, 87, 487–496. https://doi.org/10.1016/j.foodhyd.2018.08.032

Benítez-Páez, A., Kjølbæk, L., Gómez del Pulgar, E. M., Brahe, L. K., Astrup, A., Matysik, S., Schött, H.-F., Krautbauer, S., Liebisch, G., Boberska, J., Claus, S., Rampelli, S., Brigidi, P., Larsen, L. H., & Sanz, Y. (2019). A Multi-omics Approach to Unraveling the Microbiome-Mediated Effects of Arabinoxylan Oligosaccharides in Overweight Humans. MSystems, 4(4). https://doi.org/10.1128/msystems.00209-19

Wolters, M., Ahrens, J., Romaní-Pérez, M., Watkins, C., Sanz, Y., Benítez-Páez, A., Stanton, C., & Günther, K. (2019). Dietary fat, the gut microbiota, and metabolic health – A systematic review conducted within the MyNewGut project. Clinical Nutrition, 38(6), 2504–2520. https://doi.org/10.1016/j.clnu.2018.12.024

Hess, A. L., Benítez-Páez, A., Blædel, T., Larsen, L. H., Iglesias, J. R., Madera, C., Sanz, Y., & Larsen, T. M. (2019). The effect of inulin and resistant maltodextrin on weight loss during energy restriction: a randomised, placebo-controlled, double-blinded intervention. European Journal of Nutrition, 59(6), 2507–2524. https://doi.org/10.1007/s00394-019-02099-x

López-Goñi, I., Giner-Lamia, J., Álvarez-Ordoñez, A., Benitez-Páez, A., Claessen, D., Cortesao, M., de Toro, M., García-Ruano, D., Granato, E. T., Kovács, Á. T., Romalde, J. L., Sana, T. G., Sánchez-Angulo, M., Sangari, F. J., Smits, W. K., Sturm, T., Thomassin, J. L., Valdehuesa, K. N. G., & Zapotoczna, M. (2019). #EUROmicroMOOC: using Twitter to share trends in Microbiology worldwide. FEMS Microbiology Letters, 366(11). https://doi.org/10.1093/femsle/fnz141

Olivares, M., Walker, A. W., Capilla, A., Benítez-Páez, A., Palau, F., Parkhill, J., Castillejo, G., & Sanz, Y. (2018). Gut microbiota trajectory in early life may predict development of celiac disease. Microbiome, 6(1). https://doi.org/10.1186/s40168-018-0415-6

Olivares, M., Benítez-Páez, A., de Palma, G., Capilla, A., Nova, E., Castillejo, G., Varea, V., Marcos, A., Garrote, J. A., Polanco, I., Donat, E., Ribes-Koninckx, C., Calvo, C., Ortigosa, L., Palau, F., & Sanz, Y. (2018). Increased prevalence of pathogenic bacteria in the gut microbiota of infants at risk of developing celiac disease: The PROFICEL study. Gut Microbes, 1–8. https://doi.org/10.1080/19490976.2018.1451276

Cuevas-Tena, M., Gómez del Pulgar, E. M., Benítez-Páez, A., Sanz, Y., Alegría, A., & Lagarda, M. J. (2018). Plant sterols and human gut microbiota relationship: An in vitro colonic fermentation study. Journal of Functional Foods, 44, 322–329. https://doi.org/10.1016/j.jff.2018.03.023

Olivares, M., Schüppel, V., Hassan, A. M., Beaumont, M., Neyrinck, A. M., Bindels, L. B., Benítez-Páez, A., Sanz, Y., Haller, D., Holzer, P., & Delzenne, N. M. (2018). The Potential Role of the Dipeptidyl Peptidase-4-Like Activity From the Gut Microbiota on the Host Health. Frontiers in Microbiology, 9. https://doi.org/10.3389/fmicb.2018.01900

Moukadiri, I., Villarroya, M., Benítez-Páez, A., & Armengod, M.-E. (2018). Bacillus subtilis exhibits MnmC-like tRNA modification activities. RNA Biology, 15(9), 1167–1173. https://doi.org/10.1080/15476286.2018.1517012

Sanchis-Chordà, J., del Pulgar, E. M. G., Carrasco-Luna, J., Benítez-Páez, A., Sanz, Y., & Codoñer-Franch, P. (2018). Bifidobacterium pseudocatenulatum CECT 7765 supplementation improves inflammatory status in insulin-resistant obese children. European Journal of Nutrition. https://doi.org/10.1007/s00394-018-1828-5

Sanz, Y., Romaní-Perez, M., Benítez-Páez, A., Portune, K. J., Brigidi, P., Rampelli, S., Dinan, T., Stanton, C., Delzenne, N., Blachier, F., Neyrinck, A. M., Beaumont, M., Olivares, M., Holzer, P., Günther, K., Wolters, M., Ahrens, W., Claus, S. P., Campoy, C., … Kamp, J.-W. van der. (2018). Towards microbiome-informed dietary recommendations for promoting metabolic and mental health: Opinion papers of the MyNewGut project. Clinical Nutrition, 37(6), 2191–2197. https://doi.org/10.1016/j.clnu.2018.07.007

Rampelli, S., Guenther, K., Turroni, S., Wolters, M., Veidebaum, T., Kourides, Y., Molnár, D., Lissner, L., Benitez-Paez, A., Sanz, Y., Fraterman, A., Michels, N., Brigidi, P., Candela, M., & Ahrens, W. (2018). Pre-obese children’s dysbiotic gut microbiome and unhealthy diets may predict the development of obesity. Communications Biology, 1(1). https://doi.org/10.1038/s42003-018-0221-5

Benítez-Páez, A., & Sanz, Y. (2017). From Bacterial Genomics to Human Health. Fermented Foods in Health and Disease Prevention, 159–172. https://doi.org/10.1016/b978-0-12-802309-9.00008-x

Benítez-Páez, A., & Sanz, Y. (2017). Multi-locus and long amplicon sequencing approach to study microbial diversity at species level using the MinION™ portable nanopore sequencer. https://doi.org/10.1101/117143

Benítez-Páez, A., Gómez del Pulgar, E. M., & Sanz, Y. (2017). The Glycolytic Versatility of Bacteroides uniformis CECT 7771 and Its Genome Response to Oligo and Polysaccharides. Frontiers in Cellular and Infection Microbiology, 7. https://doi.org/10.3389/fcimb.2017.00383

Moya-Pérez, A., Perez-Villalba, A., Benítez-Páez, A., Campillo, I., & Sanz, Y. (2017). Bifidobacterium CECT 7765 modulates early stress-induced immune, neuroendocrine and behavioral alterations in mice. Brain, Behavior, and Immunity, 65, 43–56. https://doi.org/10.1016/j.bbi.2017.05.011

Mosquera-Rendón, J., Rada-Bravo, A. M., Cárdenas-Brito, S., Corredor, M., Restrepo-Pineda, E., & Benítez-Páez, A. (2016). Pangenome-wide and molecular evolution analyses of the Pseudomonas aeruginosa species. BMC Genomics, 17(1). https://doi.org/10.1186/s12864-016-2364-4

Benítez-Páez, A., Portune, K. J., & Sanz, Y. (2016). Species-level resolution of 16S rRNA gene amplicons sequenced through the MinION™ portable nanopore sequencer. Gigascience, 5(1). https://doi.org/10.1186/s13742-016-0111-z

Benítez-Páez, A., Moreno, F. J., Sanz, M. L., & Sanz, Y. (2016). Genome Structure of the Symbiont Bifidobacterium pseudocatenulatum CECT 7765 and Gene Expression Profiling in Response to Lactulose-Derived Oligosaccharides. Frontiers in Microbiology, 7. https://doi.org/10.3389/fmicb.2016.00624

Sanz, Y., Portune, K., Gómez Del Pulgar, E. M., & Benítez-Páez, A. (2016). Targeting the Microbiota. The Gut-Brain Axis, 17–30. https://doi.org/10.1016/b978-0-12-802304-4.00002-5

Russo, M., Fabersani, E., Abeijón-Mukdsi, M., Ross, R., Fontana, C., Benítez-Páez, A., Gauffin-Cano, P., & Medina, R. (2016). Lactobacillus fermentum CRL1446 Ameliorates Oxidative and Metabolic Parameters by Increasing Intestinal Feruloyl Esterase Activity and Modulating Microbiota in Caloric-Restricted Mice. Nutrients, 8(7), 415. https://doi.org/10.3390/nu8070415

Benítez-Páez, A., Gómez Del Pulgar, E. M., Kjølbæk, L., Brahe, L. K., Astrup, A., Larsen, L., & Sanz, Y. (2016). Impact of dietary fiber and fat on gut microbiota re-modeling and metabolic health. Trends in Food Science & Technology, 57, 201–212. https://doi.org/10.1016/j.tifs.2016.11.001

Muñoz-Gómez, A., Corredor, M., Benítez-Páez, A., & Peláez, C. (2014). iTRAQ, The High Throughput Data Analysis of Proteins to Understand Immunologic Expression in Insect. Advances in Computational Biology, 387–394. https://doi.org/10.1007/978-3-319-01568-2_54

Mosquera-Rendón, J., Cárdenas-Brito, S., Pineda, J. D., Corredor, M., & Benítez-Páez, A. (2014). Evolutionary and sequence-based relationships in bacterial AdoMet-dependent non-coding RNA methyltransferases. BMC Research Notes, 7(1). https://doi.org/10.1186/1756-0500-7-440

Muñoz-Gómez, A., Corredor, M., Benítez-Páez, A., & Peláez, C. (2014). Development of Quantitative Proteomics Using iTRAQ Based on the Immunological Response of Galleria mellonella Larvae Challenged with Fusarium oxysporum Microconidia. PLoS ONE, 9(11), e112179. https://doi.org/10.1371/journal.pone.0112179

Camelo-Castillo, A., Benítez-Páez, A., Belda-Ferre, P., Cabrera-Rubio, R., & Mira, A. (2014). Streptococcus dentisani sp. nov., a novel member of the mitis group. International Journal of Systematic and Evolutionary Microbiology, 64(Pt_3), 1073–1073. https://doi.org/10.1099/ijs.0.062802-0

Camelo-Castillo, A., Benítez-Páez, A., Belda-Ferre, P., Cabrera-Rubio, R., & Mira, A. (2014). Streptococcus dentisani sp. nov., a novel member of the mitis group. International Journal of Systematic and Evolutionary Microbiology, 64(Pt_1), 60–65. https://doi.org/10.1099/ijs.0.054098-0

Benítez-Páez, A., Álvarez, M., Belda-Ferre, P., Rubido, S., Mira, A., & Tomás, I. (2013). Detection of Transient Bacteraemia following Dental Extractions by 16S rDNA Pyrosequencing: A Pilot Study. PLoS ONE, 8(3), e57782. https://doi.org/10.1371/journal.pone.0057782

Benítez-Páez, A., Cárdenas-Brito, S., Corredor, M., Villarroya, M., & Armengod, M. E. (2013). Mutaciones en genes modificadores de ARN ribosómico y la resistencia a aminoglucósidos: el caso del gen rsmG. Biomédica, 34(0), 41. https://doi.org/10.7705/biomedica.v34i0.1702

Benítez-Páez, A., Villarroya, M., & Armengod, M.-E. (2012). The Escherichia coli RlmN methyltransferase is a dual-specificity enzyme that modifies both rRNA and tRNA and controls translational accuracy. RNA, 18(10), 1783–1795. https://doi.org/10.1261/rna.033266.112

Benítez-Páez, A., Villarroya, M., & Armengod, M.-E. (2012). Regulation of expression and catalytic activity of Escherichia coli RsmG methyltransferase. RNA, 18(4), 795–806. https://doi.org/10.1261/rna.029868.111

Armengod, M.-E., Moukadiri, I., Prado, S., Ruiz-Partida, R., Benítez-Páez, A., Villarroya, M., Lomas, R., Garzón, M. J., Martínez-Zamora, A., Meseguer, S., & Navarro-González, C. (2012). Enzymology of tRNA modification in the bacterial MnmEG pathway. Biochimie, 94(7), 1510–1520. https://doi.org/10.1016/j.biochi.2012.02.019

Benitez-Paez, A., Cardenas-Brito, S., & Gutierrez, A. J. (2011). A practical guide for the computational selection of residues to be experimentally characterized in protein families. Briefings in Bioinformatics, 13(3), 329–336. https://doi.org/10.1093/bib/bbr052

Benítez-Páez, A., Villarroya, M., Douthwaite, S., Gabaldón, T., & Armengod, M.-E. (2010). YibK is the 2′-O-methyltransferase TrmL that modifies the wobble nucleotide in Escherichia coli tRNALeu isoacceptors. RNA, 16(11), 2131–2143. https://doi.org/10.1261/rna.2245910

Benítez-Páez, A., & Cárdenas-Brito, S. (2010). Bioinformática en Colombia: presente y futuro de la investigación biocomputacional. Biomédica, 30(2), 170. https://doi.org/10.7705/biomedica.v30i2.180

Shi, R., Villarroya, M., Ruiz-Partida, R., Li, Y., Proteau, A., Prado, S., Moukadiri, I., Benítez-Páez, A., Lomas, R., Wagner, J., Matte, A., Velázquez-Campoy, A., Armengod, M.-E., & Cygler, M. (2009). Structure-Function Analysis of Escherichia coli MnmG (GidA), a Highly Conserved tRNA-Modifying Enzyme. Journal of Bacteriology, 191(24), 7614–7619. https://doi.org/10.1128/jb.00650-09

Benítez-Páez, A. (2009). Considerations to Improve Functional Annotations in Biological Databases. OMICS: A Journal of Integrative Biology, 13(6), 527–532. https://doi.org/10.1089/omi.2009.0075

Benı́tez-Páez, A., & Laverde, S. (2004). Population analysis from 12 microsatellite loci reveled by silver stain and assisted by computer software. International Congress Series, 1261, 207–209. https://doi.org/10.1016/s0531-5131(03)01495-x

Sánchez-Diz, P., Gusmão, L., Beleza, S., Benı́tez-Páez, A., Castro, A., Garcı́a, O., Solla, L. P., Geada, H., Martı́n, P., Martı́nez-Jarreta, B., de Fátima Pinheiro, M., Raimondi, E., Marı́a Silva de la Fuente, S., Vide, M. C., Whittle, M. R., Zarrabeitia, M. T., Carracedo, A., & Amorim, A. (2003). Results of the GEP-ISFG collaborative study on two Y-STRs tetraplexes: GEPY I (DYS461, GATA C4, DYS437 and DYS438) and GEPY II (DYS460, GATA A10, GATA H4 and DYS439). Forensic Science International, 135(2), 158–162. https://doi.org/10.1016/s0379-0738(03)00200-7

Vidal-Martinez, J., Benı́tez-Páez, A., & Ossa Reyes, H. (2003). Population data of new Y-chromosome STRs GATA C4, DYS438, DYS437, GATA A7.2, GATA H4, DYS439 and GATA A10 in males from Colombia. Forensic Science International, 135(3), 243–246. https://doi.org/10.1016/s0379-0738(03)00204-4

Benı́tez-Páez, A., & Reyes, H. O. (2003). Allelic frequencies at 12 STR loci in Colombian population. Forensic Science International, 136(1–3), 86–88. https://doi.org/10.1016/s0379-0738(03)00220-2

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