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Institution: IPBLN
Research Groups: Computational Biomedicine and Health Data Science
Position: Principal Investigator
Home page: http://bioinfo.ipb.csic.es
Contact email: eduardo.andres@csic.es
BCB Committee: Expertise mapping, Talent attraction and training
BCB Community: No communities assigned.
BCB Tools: miRGate, reanalyzerGSE, miARma-Seq
BCB Services: Computational Biology and Bioinformatics Unit at IPBLN
Research topics: Computational Methods, Clinical data, Model organisms, Personal medicine, Pathway analysis, Mapping, Sequence Alignment, Artificial Intelligence, Machine Learning in Biology, Data Visualization, Experimental design, Multivariate statistics, Omics, Epigenomics, 3D chromatin structure, DNA methylation, Genomics, Single-cell omics, Variant calling, Transcriptomics, Expression Profiling, RNA Sequencing (RNA-seq), Single-cell (scRNA-seq), Spatial transcriptomics, Biological Databases, Analysis packages (R, Python, etc.), Web-service, Workflow managers, Cloud Computing, Containers Computing, High-performance Computing, Parallel Computing
Biography: I completed a degree and a PhD in Biological Sciences at the Universidad Autónoma de Madrid. I began my research career in the field of bioinformatics under the mentoring of Prof. Alfonso Valencia (H index 108, >67,000 citations), working at the Spanish National Centre for Biotechnology (CNB), the Spanish National Bioinformatics Institute (ISCIII-INB), and the Spanish National Cancer Research Centre (CNIO). In 2013, I joined the Institute of Biomedicine of Seville (IBIS) as head of the Bioinformatics Unit within the Computational Biology Group led by Dr. Ana M. Rojas (H index 31, >2,900 citations). Since 2015, I have been based at the Institute of Parasitology and Biomedicine “López-Neyra” (IPBLN), collaborating closely with Dr. Javier Martín (H index 79, >32,000 citations).
In March 2025, I was appointed as a Tenured Scientist (Científico Titular) at the Spanish National Research Council (CSIC), in the specialty of “Applications of Artificial Intelligence in Life Sciences.” Over the past years, I have broadened my expertise into the areas of machine learning (ML), natural language processing (NLP), and deep learning, applying these approaches to complex biomedical data. Currently, I lead projects focused on the identification of biomarkers for complex diseases using ML methods, as well as the application of computer vision and deep learning for the analysis of medical images. These efforts support personalized medicine by facilitating diagnosis and treatment selection.
My research career has also included the development of computational tools to explore non-coding genetic regulators in human disease. Notably, I have studied miRNA–mRNA interactions across multiple cancer types, linking them to patient survival, and extended this work to autoimmune, infectious, and neurological diseases.
With over 70 scientific publications, I actively collaborate with numerous research groups, contributing to over 40 national and international research projects. I have supervised seven Master’s theses and frequently present at scientific conferences—receiving a best poster award—and contribute as a lecturer in Master’s programs, specialization diplomas, and summer courses at various Spanish universities and CSIC training initiatives.
In addition to my research activities, I serve on the editorial board of a scientific journal, participate in organizing international symposiums, and regularly act as a reviewer for more than 30 journals (conducting ~35 reviews annually). I have also been a member of evaluation panels, including the Innova call from the Spanish Association for Cancer Research, focused on transferring research findings into clinical applications.
I am also part of the IPBLN’s scientific dissemination unit, participating in outreach initiatives such as the European Researchers’ Night, student visits, and media engagement to communicate scientific findings to the public.
With 20 years of experience in bioinformatics, I have developed independent and collaborative research lines in high-level institutions, working on large-scale projects with cutting-edge technologies, including single-cell “omics” for studying SARS-CoV-2. I remain deeply committed to scientific dissemination and translational research that bridges computational biology and biomedical innovation.
Publications
García, D. J., Pulpillo-Berrocal, M. A., Ruiz, J. L., Andrés-León, E., & Terrón-Camero, L. C. (2025). Human Papillomavirus-Encoded microRNAs as Regulators of Human Gene Expression in Anal Squamous Cell Carcinoma: A Meta-Transcriptomics Study. Non-Coding RNA, 11(3), 43. https://doi.org/10.3390/ncrna11030043
Ruiz, J. L., Marin, A., Carreira de Paula, J., Gómez-Moracho, T., García Olmedo, P., Andrés-León, E., Solano Parada, J., Orantes Bermejo, F., Osuna, A., & de Pablos, L. M. (2025). Genome drafts of Lotmaria passim strains C2 and C3 isolated from honey bees in Spain. Microbiology Resource Announcements, 14(1). https://doi.org/10.1128/mra.00642-24
Rodríguez-Ubreva, J., Calafell-Segura, J., Calvillo, C. L., Keller, B., Ciudad, L., Handfield, L.-F., de la Calle-Fabregat, C., Godoy-Tena, G., Andrés-León, E., Hoo, R., Porter, T., Prigmore, E., Hofmann, M., Decker, A., Martín, J., Vento-Tormo, R., Warnatz, K., & Ballestar, E. (2024). COVID-19 progression and convalescence in common variable immunodeficiency patients show dysregulated adaptive immune responses and persistent type I interferon and inflammasome activation. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-54732-x
Borrego-Yaniz, G., Terrón-Camero, L. C., Kerick, M., Andrés-León, E., & Martin, J. (2024). A holistic approach to understanding immune-mediated inflammatory diseases: bioinformatic tools to integrate omics data. Computational and Structural Biotechnology Journal, 23, 96–105. https://doi.org/10.1016/j.csbj.2023.11.045
Fernández-Rengel, I., Terrón-Camero, L. C., & Andrés-León, E. (2024). Inter-kingdom Signalling: Exploring the Relationships Among Microorganisms and MicroRNAs in Human Health. MiRNAs, Human Health and Diseases, 337–373. https://doi.org/10.1007/978-3-031-64788-8_12
Guzmán-Carrasco, A., Kapravelou, G., López-Jurado, M., Bermúdez, F., Andrés-León, E., Terrón-Camero, L. C., Prados, J., Melguizo, C., Porres, J. M., & Martínez, R. (2024). A Novel Plant-Based Nutraceutical Combined with Exercise Can Revert Oxidative Status in Plasma and Liver in a Diet-Induced-Obesity Animal Model. Antioxidants, 13(3), 274. https://doi.org/10.3390/antiox13030274
López-Mejías, R., Pulito-Cueto, V., Fernández Rengel, I., Terron Camero, L. C., Batista-Liz, J., Sebastián Mora-Gil, M., Leonardo, M. T., Peñalba, A., Martín-Penagos, L., Belmar-Vega, L., Gomez-Fernandez, C., Gabrie, L., Gálvez-Sánchez, R., Caminal-Montero, L., Turrión, A. I., Quiroga Colina, P., Vicente-Rabaneda, E., Sevilla-Pérez, B., Callejas, J. L., … Blanco, R. (2024). POS0256 THE FIRST METHYLOME PROFILING STUDY OF B-CELLS IN IGA VASCULITIS REVEALED POTENTIAL BIOMARKERS OF DISEASE SUSCEPTIBILITY. Annals of the Rheumatic Diseases, 83, 276. https://doi.org/10.1136/annrheumdis-2024-eular.117
Martinez-Lopez, J., Estupiñán-Moreno, E., Ortiz-Fernández, L., Kerick, M., Andrés-León, E., Terrón-Camero, L. C., Carnero-Montoro, E., Barturen, G., Beretta, L., Clinical Consortium, P., Alarcon-Riquelme, M., Acosta-Herrera, M., Ballestar, E., & Martin, J. (2024). POS0056 UNVEILING VASCULAR, PRO-FIBROTIC AND INTERFERON-RELATED ABNORMALITIES THROUGH AN EPIGENOME-WIDE ANALYSIS IN SYSTEMIC SCLEROSIS. Annals of the Rheumatic Diseases, 83, 289–290. https://doi.org/10.1136/annrheumdis-2024-eular.4879
Borrego-Yaniz, G., Estupiñán-Moreno, E., Ortiz-Fernández, L., Andrés-León, E., Terrón-Camero, L. C., González-Gay, M. Á., Castañeda, S., Guggino, G., Saadoun, D., Lio, P., Fontana, S., Márquez, A., Bonacini, M., Rossi, A., Muratore, F., Salvarani, C., Pipitone, N., Croci, S., & Martin, J. (2024). OP0025 GENOME-WIDE DNA METHYLATION STUDY REVEALS SPECIFIC SIGNATURES IN THE AFFECTED ARTERIAL TISSUE OF GIANT CELL ARTERITIS PATIENTS. Annals of the Rheumatic Diseases, 83, 33–34. https://doi.org/10.1136/annrheumdis-2024-eular.4859
Salas-Espejo, E., Terrón-Camero, L. C., Molina, N. M., Sola-Leyva, A., Pérez-Prieto, I., Vargas, E., Canha-Gouveia, A., Folch, B. A., Molina Romero, M., Rodríguez Guirado, S., Castilla-Alcala, J. A., Andrés-León, E., & Altmäe, S. (2024). O-305 Mapping the entire functionally active seminal microbiota and its association with semen quality parameters. Human Reproduction, 39(Supplement_1). https://doi.org/10.1093/humrep/deae108.362
Sola-Leyva, A., Canha-Gouveia, A., Pérez-Prieto, I., Salas-Espejo, E., Molina, N. M., Vargas, E., Terrón-Camero, L., Andrés-León, E., Fontes-Jiménez, J., Castilla, J. A., Vela-Moreno, S., Modhukur, V., Saare, M., Salumets, A., & Altmäe, S. (2024). O-268 Re-considering the endometrial microbiome: a comparison of DNA- and RNA-based sequencing techniques within the same cohort. Human Reproduction, 39(Supplement_1). https://doi.org/10.1093/humrep/deae108.315
Perurena-Prieto, J., Sanz-Martínez, M. T., Viñas-Giménez, L., Codina-Clavaguera, C., Triginer, L., Gordillo-González, F., Andrés-León, E., Batlle-Masó, L., Martin, J., Selva-O’Callaghan, A., Pujol, R., McHugh, N. J., Tansley, S. L., Colobran, R., Guillen-Del-Castillo, A., & Simeón-Aznar, C. P. (2024). Expanding the landscape of systemic sclerosis-related autoantibodies through RNA immunoprecipitation coupled with massive parallel sequencing. Journal of Autoimmunity, 149, 103328. https://doi.org/10.1016/j.jaut.2024.103328
Plaza-Florido, A., Gálvez, B. G., López, J. A., Santos-Lozano, A., Zazo, S., Rincón-Castanedo, C., Martín-Ruiz, A., Lumbreras, J., Terron-Camero, L. C., López-Soto, A., Andrés-León, E., González-Murillo, Á., Rojo, F., Ramírez, M., Lucia, A., & Fiuza-Luces, C. (2024). Exercise and tumor proteome: insights from a neuroblastoma model. Physiological Genomics, 56(12), 833–844. https://doi.org/10.1152/physiolgenomics.00064.2024
Ruiz, J. L., Terrón-Camero, L. C., Castillo-González, J., Fernández-Rengel, I., Delgado, M., Gonzalez-Rey, E., & Andrés-León, E. (2023). reanalyzerGSE: tackling the everlasting lack of reproducibility and reanalyses in transcriptomics. https://doi.org/10.1101/2023.07.12.548663
Barmada, A., Handfield, L., Godoy‐Tena, G., de la Calle‐Fabregat, C., Ciudad, L., Arutyunyan, A., Andrés‐León, E., Hoo, R., Porter, T., Oszlanczi, A., Richardson, L., Calero‐Nieto, F. J., Wilson, N. K., Marchese, D., Sancho‐Serra, C., Carrillo, J., Presas‐Rodríguez, S., Ramo‐Tello, C., Ruiz‐Sanmartin, A., … Rodríguez‐Ubreva, J. (2023). Single‐cell multi‐omics analysis of COVID‐19 patients with pre‐existing autoimmune diseases shows aberrant immune responses to infection. European Journal of Immunology, 54(1). Portico. https://doi.org/10.1002/eji.202350633
Salas-Espejo, E., Terrón-Camero, L. C., Ruiz, J. L., Molina, N. M., & Andrés-León, E. (2023). Exploring the Microbiome in Human Reproductive Tract: High-Throughput Methods for the Taxonomic Characterization of Microorganisms. Seminars in Reproductive Medicine, 41(05), 125–143. CLOCKSS. https://doi.org/10.1055/s-0044-1779025
Ramírez-Mena, A., Andrés-León, E., Alvarez-Cubero, M. J., Anguita-Ruiz, A., Martinez-Gonzalez, L. J., & Alcala-Fdez, J. (2023). Explainable artificial intelligence to predict and identify prostate cancer tissue by gene expression. Computer Methods and Programs in Biomedicine, 240, 107719. https://doi.org/10.1016/j.cmpb.2023.107719
Castillo-González, J., Ruiz, J. L., Serrano-Martínez, I., Forte-Lago, I., Ubago-Rodriguez, A., Caro, M., Pérez-Gómez, J. M., Benítez-Troncoso, A., Andrés-León, E., Sánchez-Navarro, M., Luque, R. M., & González-Rey, E. (2023). Cortistatin deficiency reveals a dysfunctional brain endothelium with impaired gene pathways, exacerbated immune activation, and disrupted barrier integrity. Journal of Neuroinflammation, 20(1). https://doi.org/10.1186/s12974-023-02908-5
Chica‐Redecillas, L., Cuenca‐Lopez, S., Andres‐Leon, E., Terron‐Camero, L. C., Cano‐Gutierrez, B., Cozar, J. M., Lorente, J. A., Vazquez‐Alonso, F., Martinez‐Gonzalez, L. J., & Alvarez‐Cubero, M. J. (2023). Multi‐omic study to unmask genes involved in prostate cancer development in a multi‐case family. Cancer Communications, 44(3), 443–447. Portico. https://doi.org/10.1002/cac2.12501
Medina-Carmona, E., Gutierrez-Rus, L. I., Manssour-Triedo, F., Newton, M. S., Gamiz-Arco, G., Mota, A. J., Reiné, P., Cuerva, J. M., Ortega-Muñoz, M., Andrés-León, E., Ortega-Roldan, J. L., Seelig, B., Ibarra-Molero, B., & Sanchez-Ruiz, J. M. (2022). Cell survival enabled by leakage of a labile metabolic intermediate. https://doi.org/10.1101/2022.05.20.492833
Rodríguez-Caparrós, A., Álvarez-Santiago, J., López-Castellanos, L., Ruiz-Rodríguez, C., Valle-Pastor, M. J., López-Ros, J., Angulo, Ú., Andrés-León, E., Suñé, C., & Hernández-Munain, C. (2022). Differently Regulated Gene-Specific Activity of Enhancers Located at the Boundary of Subtopologically Associated Domains: TCRα Enhancer. The Journal of Immunology, 208(4), 910–928. https://doi.org/10.4049/jimmunol.2000864
Molina-Sánchez, M. D., García-Rodríguez, F. M., Andrés-León, E., & Toro, N. (2022). Identification of Group II Intron RmInt1 Binding Sites in a Bacterial Genome. Frontiers in Molecular Biosciences, 9. https://doi.org/10.3389/fmolb.2022.834020
Linares‐Pineda, T. M., Boughanem, H., Gutiérrez‐Repiso, C., Macías‐González, M., Andrés‐León, E., Rojo‐Martínez, G., Valdés, S., Tinahones, F. J., & Morcillo, S. (2022). Epigenetic changes in the metabolically healthy obese: A case‐control versus a prospective study. European Journal of Clinical Investigation, 52(8). Portico. https://doi.org/10.1111/eci.13783
García-Domínguez, D. J., Hajji, N., López-Alemany, R., Sánchez-Molina, S., Figuerola-Bou, E., Morón Civanto, F. J., Rello-Varona, S., Andrés-León, E., Benito, A., Keun, H. C., Mora, J., Tirado, Ó. M., de Álava, E., & Hontecillas-Prieto, L. (2022). Selective histone methyltransferase G9a inhibition reduces metastatic development of Ewing sarcoma through the epigenetic regulation of NEU1. Oncogene, 41(18), 2638–2650. https://doi.org/10.1038/s41388-022-02279-w
Benitez, R., Caro, M., Andres‐Leon, E., O’Valle, F., & Delgado, M. (2022). Cortistatin regulates fibrosis and myofibroblast activation in experimental hepatotoxic‐ and cholestatic‐induced liver injury. British Journal of Pharmacology, 179(10), 2275–2296. Portico. https://doi.org/10.1111/bph.15752
García-Hernández, R., Perea-Martínez, A., Manzano, J. I., Terrón-Camero, L. C., Andrés-León, E., & Gamarro, F. (2022). Transcriptome Analysis of Intracellular Amastigotes of Clinical Leishmania infantum Lines from Therapeutic Failure Patients after Infection of Human Macrophages. Microorganisms, 10(7), 1304. https://doi.org/10.3390/microorganisms10071304
Alcina, A., Fedetz, M., Vidal-Cobo, I., Andrés-León, E., García-Sánchez, M.-I., Barroso-del-Jesus, A., Eichau, S., Gil-Varea, E., Luisa-Maria Villar, Saiz, A., Leyva, L., Vandenbroeck, K., Otaegui, D., Izquierdo, G., Comabella, M., Urcelay, E., & Matesanz, F. (2022). Identification of the genetic mechanism that associates L3MBTL3 to multiple sclerosis. Human Molecular Genetics, 31(13), 2155–2163. https://doi.org/10.1093/hmg/ddac009
Mencucci, M. V., Rojas-Mendoza, A. M., Andrés-León, E., Román, C. L., Gagliardino, J. J., Abba, M. C., & Maiztegui, B. (2022). Identification of novel microRNAs associated with type 2 diabetes by an integrative bioinformatic analysis. Human Gene, 34, 201125. https://doi.org/10.1016/j.humgen.2022.201125
Terrón-Camero, L. C., Gordillo-González, F., Salas-Espejo, E., & Andrés-León, E. (2022). Comparison of Metagenomics and Metatranscriptomics Tools: A Guide to Making the Right Choice. Genes, 13(12), 2280. https://doi.org/10.3390/genes13122280
García-Domínguez, D. J., Hajji, N., Sánchez-Molina, S., Figuerola-Bou, E., de Pablos, R. M., Espinosa-Oliva, A. M., Andrés-León, E., Terrón-Camero, L. C., Flores-Campos, R., Pascual-Pasto, G., Robles, M. J., Carcaboso, Á. M., Mora, J., de Álava, E., & Hontecillas-Prieto, L. (2021). HDAC6 regulates expression of the oncogenic driver EWSR1-FLI1 through theEWSR1promoter in Ewing sarcoma. https://doi.org/10.1101/2021.01.04.425179
Rodríguez-Ubreva, J., Arutyunyan, A., Bonder, M. J., Pino-Molina, L. D., Clark, S. J., de la Calle-Fabregat, C., Garcia-Alonso, L., Handfield, L.-F., Ciudad, L., Andrés-León, E., Krueger, F., Català-Moll, F., Rodríguez-Cortez, V. C., Polanski, K., Mamanova, L., van Dongen, S., Kiselev, V. Yu., Martínez-Saavedra, M. T., Heyn, H., … Ballestar, E. (2021). Single-Cell Atlas of Common Variable Immunodeficiency reveals germinal center-associated epigenetic dysregulation in B cell responses. https://doi.org/10.1101/2021.12.20.473453
Marin, F. R., Dávalos, A., Kiltschewskij-Brown, D., Crespo, M. C., Cairns, M., Andres-Leon, E., & Soler-Rivas, C. (2021). RNA-seq, bioinformatic identification of potential MicroRNA-Like Small RNAs in the edible mushroom Agaricus bisporus and experimental approach for their validation. https://doi.org/10.1101/2021.10.13.464216
López-Jiménez, E., & Andrés-León, E. (2021). The Implications of ncRNAs in the Development of Human Diseases. Non-Coding RNA, 7(1), 17. https://doi.org/10.3390/ncrna7010017
Martínez-González, L., Sánchez-Conde, V., González-Cabezuelo, J., Antunez-Rodríguez, A., Andrés-León, E., Robles-Fernandez, I., Lorente, J., Vázquez-Alonso, F., & Alvarez-Cubero, M. (2021). Identification of MicroRNAs as Viable Aggressiveness Biomarkers for Prostate Cancer. Biomedicines, 9(6), 646. https://doi.org/10.3390/biomedicines9060646
Martínez-Blanco, Á., Domínguez-Pantoja, M., Botía-Sánchez, M., Pérez-Cabrera, S., Bello-Iglesias, N., Carrillo-Rodríguez, P., Martin-Morales, N., Lario-Simón, A., Pérez-Sánchez-Cañete, M. M., Montosa-Hidalgo, L., Guerrero-Fernández, S., Longobardo-Polanco, V. M., Redondo-Sánchez, S., Cornet-Gomez, A., Torres-Sáez, M., Fernández-Ibáñez, A., Terrón-Camero, L., Andrés-León, E., O’Valle, F., … Sancho, J. (2021). CD38 Deficiency Ameliorates Chronic Graft-Versus-Host Disease Murine Lupus via a B-Cell-Dependent Mechanism. Frontiers in Immunology, 12. https://doi.org/10.3389/fimmu.2021.713697
Casares-Marfil, D., Kerick, M., Andrés-León, E., Bosch-Nicolau, P., Molina, I., Martin, J., & Acosta-Herrera, M. (2021). GWAS loci associated with Chagas cardiomyopathy influences DNA methylation levels. PLOS Neglected Tropical Diseases, 15(10), e0009874. https://doi.org/10.1371/journal.pntd.0009874
Li, T., Ortiz, L., Andrés-León, E., Ciudad, L., Javierre, B. M., López-Isac, E., Guillén-Del-Castillo, A., Simeón-Aznar, C. P., Ballestar, E., & Martin, J. (2020). Epigenomics and Transcriptomics of Systemic Sclerosis CD4+ T cells reveal Long Range Dysregulation of Key Inflammatory Pathways mediated by disease-associated Susceptibility Loci. https://doi.org/10.1101/2020.03.14.20036061
Luzon-Hidalgo, R., Risso, V. A., Delgado, A., Andrés-Leon, E., Ibarra-Molero, B., & Sanchez-Ruiz, J. M. (2020). Evidence for a role of phenotypic mutations in virus adaptation. https://doi.org/10.1101/2020.08.21.261495
García-Domínguez, D. J., Hontecillas-Prieto, L., León, E. A., Sánchez-Molina, S., Rodríguez-Núñez, P., Morón, F. J., Hajji, N., Mackintosh, C., & de Álava, E. (2020). An inducible ectopic expression system of EWSR1-FLI1 as a tool for understanding Ewing sarcoma oncogenesis. PLOS ONE, 15(6), e0234243. https://doi.org/10.1371/journal.pone.0234243
Ballestar, E., Farber, D. L., Glover, S., Horwitz, B., Meyer, K., Nikolić, M., Ordovas-Montanes, J., Sims, P., Shalek, A., Vandamme, N., Vandekerckhove, L., Vento-Tormo, R., & Villani, A. C. (2020). Single cell profiling of COVID-19 patients: an international data resource from multiple tissues. https://doi.org/10.1101/2020.11.20.20227355
Fernández-Cortés, M., Andrés-León, E., & Oliver, F. J. (2020). The PARP Inhibitor Olaparib Modulates the Transcriptional Regulatory Networks of Long Non-Coding RNAs during Vasculogenic Mimicry. Cells, 9(12), 2690. https://doi.org/10.3390/cells9122690
Lopez-Jimenez, E., de Aja, J. S., Badia-Careaga, C., Barral, A., Rollan, I., Rouco, R., Santos, E., Tiana, M., Victorino, J., Sanchez-Iranzo, H., Acemel, R. D., Torroja, C., Adan, J., Andres-Leon, E., Gomez-Skarmeta, J. L., Giovinazzo, G., Sanchez-Cabo, F., & Manzanares, M. (2019). Pluripotency factors regulate the onset of Hox cluster activation in the early embryo. https://doi.org/10.1101/564658
Andrés-León, E., & Rojas, A. M. (2019). miARma-Seq, a comprehensive pipeline for the simultaneous study and integration of miRNA and mRNA expression data. Methods, 152, 31–40. https://doi.org/10.1016/j.ymeth.2018.09.002
López-Nieva, P., Fernández-Navarro, P., Graña-Castro, O., Andrés-León, E., Santos, J., Villa-Morales, M., Cobos-Fernández, M. Á., González-Sánchez, L., Malumbres, M., Salazar-Roa, M., & Fernández-Piqueras, J. (2019). Detection of novel fusion-transcripts by RNA-Seq in T-cell lymphoblastic lymphoma. Scientific Reports, 9(1). https://doi.org/10.1038/s41598-019-41675-3
Egui, A., Thomas, M. C., Fernández-Villegas, A., Pérez-Antón, E., Gómez, I., Carrilero, B., del Pozo, Á., Ceballos, M., Andrés-León, E., López-Ruz, M. Á., Gainza, E., Oquiñena, E., Segovia, M., & López, M. C. (2019). A Parasite Biomarker Set for Evaluating Benznidazole Treatment Efficacy in Patients with Chronic Asymptomatic Trypanosoma cruzi Infection. Antimicrobial Agents and Chemotherapy, 63(10). https://doi.org/10.1128/aac.02436-18
Saura, A., Iribarren, P. A., Rojas‐Barros, D., Bart, J. M., López‐Farfán, D., Andrés‐León, E., Vidal‐Cobo, I., Boehm, C., Alvarez, V. E., Field, M. C., & Navarro, M. (2019). SUMOylated SNF2PH promotes variant surface glycoprotein expression in bloodstream trypanosomes. EMBO Reports, 20(12). Portico. https://doi.org/10.15252/embr.201948029
Andrés-León, E., Núñez-Torres, R., & Rojas, A. M. (2018). Correction: Corrigendum: miARma-Seq: a comprehensive tool for miRNA, mRNA and circRNA analysis. Scientific Reports, 8(1). https://doi.org/10.1038/srep46928
Lynch, C. J., Bernad, R., Calvo, I., Nóbrega-Pereira, S., Ruiz, S., Ibarz, N., Martinez-Val, A., Graña-Castro, O., Gómez-López, G., Andrés-León, E., Espinosa Angarica, V., del Sol, A., Ortega, S., Fernandez-Capetillo, O., Rojo, E., Munoz, J., & Serrano, M. (2018). The RNA Polymerase II Factor RPAP1 Is Critical for Mediator-Driven Transcription and Cell Identity. Cell Reports, 22(2), 396–410. https://doi.org/10.1016/j.celrep.2017.12.062
López-Jiménez, E., Rojas, A. M., & Andrés-León, E. (2018). RNA sequencing and Prediction Tools for Circular RNAs Analysis. Circular RNAs, 17–33. https://doi.org/10.1007/978-981-13-1426-1_2
García-Rodríguez, S., Rosal-Vela, A., Botta, D., Cumba Garcia, L. M., Zumaquero, E., Prados-Maniviesa, V., Cerezo-Wallis, D., Lo Buono, N., Robles-Guirado, J.-Á., Guerrero, S., González-Paredes, E., Andrés-León, E., Corbí, Á., Mack, M., Koch-Nolte, F., Merino, R., Zubiaur, M., Lund, F. E., & Sancho, J. (2018). CD38 promotes pristane-induced chronic inflammation and increases susceptibility to experimental lupus by an apoptosis-driven and TRPM2-dependent mechanism. Scientific Reports, 8(1). https://doi.org/10.1038/s41598-018-21337-6
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Research lines:
Funding:
- Implementación de tecnologías de transcriptómica espacial de resolución celular con aplicación biosanitaria y desarrollo de métodos coordinados de análisis bioinformáticos estandarizados: Junta de Andalucia + Ministerio de Ciencia, Innovación y Universidades. National/Regional. 01/06/23 - 01/06/2025.
- Development of HPC and AI-Based Tools for Large-Scale Spatial Transcriptomics and Single-Cell Data Integration: Generation D initiative, promoted by Red.es, an organization attached to the Ministry for Digital Transformation and the Civil Service, for the attraction and retention of talent through grants and training contracts, financed by the Recovery, Transformation and Resilience Plan through the European Union’s Next Generation funds. National. 20/12/2024 - 19/12/2028.
More info
Participation in:
Master Programs: UPO - Advanced Master on Bioinformatics CNIC - Master on Clinical Bioinformatics UPO - Expert Diploma in Bioinformatics and Data Analysis
Other Participation: csicconexion, csicpt