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Institution: IHSM
Research Groups: Plant-virus interaction, Machine Learning in Multi-Omics (MLiMO)
Contact email: ian.morilla@ihsm.uma-csic.es
BCB Committee: No committees assigned.
BCB Community: No communities assigned.
BCB Tools: S<sup>2</sup>-PepAnalyst, TaelCore, CoMM-BIP, GeoTop
BCB Services:
Research topics: Computational Methods, Applications of Computational Biology, Clinical data, Microbial Communities, Personal medicine, Plant genomics, Computational models and simulations, Gene regulatory networks, Functional genomics, Function prediction, Systems Biology, Integrative Analysis, Network Biology, Pathway analysis, Regulatory biology, Data Analysis, Artificial Intelligence, Deep Learning in Biology, Large language models, Machine Learning in Biology, Statistical Methods for Biology, Omics
Publications
Gouiaa, F., Vomo-Donfack, K. L., Tran-Dinh, A., & Morilla, I. (2024). Novel dimensionality reduction method, Taelcore, enhances lung transplantation risk prediction. Computers in Biology and Medicine, 169(107969), 107969. doi:10.1016/j.compbiomed.2024.107969
Gauthier, S., Tran-Dinh, A., & Morilla, I. (2023). Plasma proteome dynamics of COVID-19 severity learnt by a graph convolutional network of multi-scale topology. Life Science Alliance, 6(5), e202201624. doi:10.26508/lsa.202201624
Abaach, M., & Morilla, I. (2023). GeoTop: Advancing image classification with geometric-topological analysis. Retrieved from http://arxiv.org/abs/2311.16157
Tran-Dinh, A., Laurent, Q., Even, G., Tanaka, S., Lortat-Jacob, B., Castier, Y., … Morilla, I. (2022). Personalized risk predictor for acute cellular rejection in lung transplant using soluble CD31. Scientific Reports, 12(1), 17628. doi:10.1038/s41598-022-21070-1
Benadjaoud, M. A., Soysouvanh, F., Tarlet, G., Paget, V., Buard, V., Santos de Andrade, H., … Milliat, F. (2022). Deciphering the dynamic molecular program of radiation-induced endothelial senescence. International Journal of Radiation Oncology, Biology, Physics, 112(4), 975–985. doi:10.1016/j.ijrobp.2021.11.019
Morilla, I., Chan, P., Caffin, F., Svilar, L., Selbonne, S., Ladaigue, S., … Guipaud, O. (2022). Deep models of integrated multiscale molecular data decipher the endothelial cell response to ionizing radiation. iScience, 25(1), 103685. doi:10.1016/j.isci.2021.103685
Morilla, I., Uzzan, M., Cazals-Hatem, D., Colnot, N., Panis, Y., Nancey, S., … Daniel, F. (2021). Computational learning of microRNA-based prediction of pouchitis outcome after restorative proctocolectomy in patients with ulcerative colitis. Inflammatory Bowel Diseases, 27(10), 1653–1660. doi:10.1093/ibd/izab030
Morilla, I. (2020). A deep learning approach to evaluate intestinal fibrosis in magnetic resonance imaging models. Neural Computing & Applications, 32(18), 14865–14874. doi:10.1007/s00521-020-04838-2
Morilla, I., Uzzan, M., Laharie, D., Cazals-Hatem, D., Denost, Q., Daniel, F., … Treton, X. (2019). Colonic MicroRNA profiles, identified by a deep learning algorithm, that predict responses to therapy of patients with acute severe ulcerative colitis. Clinical Gastroenterology and Hepatology: The Official Clinical Practice Journal of the American Gastroenterological Association, 17(5), 905–913. doi:10.1016/j.cgh.2018.08.068
Sharma, A., Heinze, S. D., Wu, Y., Kohlbrenner, T., Morilla, I., Brunner, C., … Bopp, D. (2017). Male sex in houseflies is determined by Mdmd , a paralog of the generic splice factor gene CWC22. Science (New York, N.Y.), 356(6338), 642–645. doi:10.1126/science.aam5498
Research lines:
Funding:
- Decoding vector-induced gene regulation in plant-insect-virus causal diagrams: Consejería de Universidad, Investigación e Innovación de la Junta de Andalucía (ProyExcel_00499). Regional, EU. 28/02/2023 - 27/02/2026.
- Charting the shared basis of Cancer, Autoimmune, and Cardiovascular diseases using multi-scale Topology and Optimal Transport: Collège des Écoles Doctorales de France . International. 01/10/2023-30/09/2026.
- TRANSCEND-ID. Approches intégratives d’Intelligence Artificielle et de la biologie pour la modélisation de l’inflammation chronique: Agence nationale de la recherche. International. 20/07/2025-19/07/2030.
- Computational identification of small signalling peptides: University of Malaga (B1-2022_29). Regional. 01/03/2023-31/03/2024.
- MMD-LLC: Labex Infibrex - Université Paris Cité. International. 20/07/2025 - 19/07/2028.