Detalle de: Simulating Evolution in Asexual Populations with Epistasis
| Title | Simulating Evolution in Asexual Populations with Epistasis |
| Abstract |
I show how to use OncoSimulR, software for forward-time genetic simulations, to simulate evolution of asexual populations in the presence of epistatic interactions. This chapter emphasizes the specification of fitness and epistasis, both directly (i.e., specifying the effects of individual mutations and their epistatic interactions) and indirectly (using models for random fitness landscapes). |
| Apa Reference | Diaz-Uriarte, R. (2021). Simulating Evolution in Asexual Populations with Epistasis. Epistasis, 121–154. 10.1007/978-1-0716-0947-7_9 |
| Doi | 10.1007/978-1-0716-0947-7_9 |
| Publication Date | 2021 |
| Publication Type | Book / chapter |
| Ontology | Bioinformatics Software and Tools, Computational models and simulations, Evolutionary modelling |
| Researchers | Ramon Díaz Uriarte |
| Research Groups | Bioinformatics and Computational Biology in Cancer Evolution |
| Tools |