Research topics: Applications of Computational Biology, Artificial Intelligence, Bioinformatics Infrastructure, Biological Databases, Biological interpretation, Clinical data, Computational Methods, Data Analysis, Data Repositories, Deep Learning in Biology, Integrative Analysis, Machine Learning in Biology, Metabolomics, Metagenomics, Microbial Communities, Microbial communities, Natural Language Processing (NLP), Network Biology, Pathway analysis, Pathway analysis, Personal medicine, Systems Biology, Text mining
Publications
Romero-Tapiador, S., Tolosana, R., Morales, A., Fierrez, J., Vera-Rodriguez, R., Espinosa-Salinas, I., Freixer, G., Carrillo de Santa Pau, E., Ramírez de Molina, A., & Ortega-Garcia, J. (2024). Leveraging automatic personalised nutrition: food image recognition benchmark and dataset based on nutrition taxonomy. Multimedia Tools and Applications, 84(4), 1945–1966. https://doi.org/10.1007/s11042-024-19161-4
Romero-Tapiador, S., Tolosana, R., Morales, A., Fierrez, J., Vera-Rodriguez, R., Espinosa-Salinas, I., Freixer, G., de Santa Pau, E. C., de Molina, A. R., & Ortega-Garcia, J. (2023). AI4Food-NutritionFW: A Novel Framework for the Automatic Synthesis and Analysis of Eating Behaviours. IEEE Access, 11, 112199–112211. https://doi.org/10.1109/access.2023.3322770
Solorzano, J., Carrillo-de Santa Pau, E., Laguna, T., & Busturia, A. (2023). A genome-wide computational approach to define microRNA-Polycomb/trithorax gene regulatory circuits in Drosophila. Developmental Biology, 495, 63–75. https://doi.org/10.1016/j.ydbio.2022.12.008
Molina, V. M. L., Lacruz-Pleguezuelos, B., Carrillo de Santa Pau, E., & Marcos-Zambrano, L. J. (2023). Uncovering the link between gut microbiome, highly processed food consumption and diet quality through bioinformatics methods. https://doi.org/10.1101/2023.03.07.530223
Marqués, M., Tranchant, R., Risa-Ebrí, B., Suárez-Solís, M. L., Fernández, L. C., Carrillo-de-Santa-Pau, E., del Pozo, N., Martínez de Villarreal, J., Meiller, C., Allory, Y., Blum, Y., Pirker, C., Hegedus, B., Barry, S. T., Carnero, A., Berger, W., Jean, D., & Real, F. X. (2023). Supplementary Data from Combined MEK and PI3K/p110β Inhibition as a Novel Targeted Therapy for Malignant Mesothelioma Displaying Sarcomatoid Features. https://doi.org/10.1158/0008-5472.22425411.v1
Marqués, M., Tranchant, R., Risa-Ebrí, B., Suárez-Solís, M. L., Fernández, L. C., Carrillo-de-Santa-Pau, E., del Pozo, N., Martínez de Villarreal, J., Meiller, C., Allory, Y., Blum, Y., Pirker, C., Hegedus, B., Barry, S. T., Carnero, A., Berger, W., Jean, D., & Real, F. X. (2023). Data from Combined MEK and PI3K/p110β Inhibition as a Novel Targeted Therapy for Malignant Mesothelioma Displaying Sarcomatoid Features. https://doi.org/10.1158/0008-5472.c.6512028
Romero-Tapiador, S., Lacruz-Pleguezuelos, B., Tolosana, R., Freixer, G., Daza, R., Fernández-Díaz, C. M., Aguilar-Aguilar, E., Fernández-Cabezas, J., Cruz-Gil, S., Molina, S., Crespo, M. C., Laguna, T., Marcos-Zambrano, L. J., Vera-Rodriguez, R., Fierrez, J., Ramírez de Molina, A., Ortega-Garcia, J., Espinosa-Salinas, I., Morales, A., & Carrillo de Santa Pau, E. (2023). AI4FoodDB: a database for personalized e-Health nutrition and lifestyle through wearable devices and artificial intelligence. Database, 2023. https://doi.org/10.1093/database/baad049
Laguna, T., Piette-Gómez, O., Garranzo, M., Gómez de Cedrón, M., Ramírez de Molina, A., & Carrillo de Santa Pau, E. (2023). EPIGENOMIC VARIABILITY AND TRANSCRIPTOMICS AS A NOVEL MULTIOMIC COMPLEMENTARY APPROACH FOR PERSONALIZED NUTRITION IN COLORECTAL CANCER PATIENTS. https://doi.org/10.1101/2023.07.19.549686
D’Elia, D., Truu, J., Lahti, L., Berland, M., Papoutsoglou, G., Ceci, M., Zomer, A., Lopes, M. B., Ibrahimi, E., Gruca, A., Nechyporenko, A., Frohme, M., Klammsteiner, T., Pau, E. C. S., Marcos-Zambrano, L. J., Hron, K., Pio, G., Simeon, A., Suharoschi, R., … Claesson, M. J. (2023). Advancing microbiome research with machine learning: key findings from the ML4Microbiome COST action. Frontiers in Microbiology, 14. https://doi.org/10.3389/fmicb.2023.1257002
Marcos-Zambrano, L. J., Lacruz-Plegezuelos, B., Valdés, A., Aguilar-Aguilar, E., Loria-Kohen, V., Cifuentes, A., Ramírez de Molina, A., & Carrillo de Santa Pau, E. (2023). Non-responsive Celiac disease symptoms associated with microbiome network structure and function. https://doi.org/10.1101/2023.10.14.562350
Lacruz-Pleguezuelos, B., Piette, O., Garranzo, M., Pérez-Serrano, D., Milešević, J., Espinosa-Salinas, I., Ramírez de Molina, A., Laguna, T., & Carrillo de Santa Pau, E. (2023). FooDrugs: a comprehensive food–drug interactions database with text documents and transcriptional data. Database, 2023. https://doi.org/10.1093/database/baad075
Marcos-Zambrano, L. J., López-Molina, V. M., Bakir-Gungor, B., Frohme, M., Karaduzovic-Hadziabdic, K., Klammsteiner, T., Ibrahimi, E., Lahti, L., Loncar-Turukalo, T., Dhamo, X., Simeon, A., Nechyporenko, A., Pio, G., Przymus, P., Sampri, A., Trajkovik, V., Lacruz-Pleguezuelos, B., Aasmets, O., Araujo, R., … Carrillo de Santa Pau, E. (2023). A toolbox of machine learning software to support microbiome analysis. Frontiers in Microbiology, 14. https://doi.org/10.3389/fmicb.2023.1250806
Garcia, S., Ordoñez, S., López-Molina, V. M., Lacruz-Pleguezuelos, B., Carrillo de Santa Pau, E., & Marcos-Zambrano, L. J. (2023). Citizen science helps to raise awareness about gut microbiome health in people at risk of developing non-communicable diseases. Gut Microbes, 15(1). https://doi.org/10.1080/19490976.2023.2241207
Milton-Laskibar, I., Marcos-Zambrano, L. J., Gómez-Zorita, S., Carrillo de Santa Pau, E., Fernández-Quintela, A., Martínez, J. A., & Portillo, M. P. (2022). Involvement of microbiota and short-chain fatty acids on non-alcoholic steatohepatitis when induced by feeding a hypercaloric diet rich in saturated fat and fructose. Gut Microbiome, 3. https://doi.org/10.1017/gmb.2022.2
Garcia, S., Ordoñez, S., de Santa Pau, E. C., & Marcos-Zambrano, L. J. (2022). Photovoice methodology to raise citizen awareness about the role of the gut microbiome in Non-Communicable Diseases: A pilot study. https://doi.org/10.1101/2022.06.17.22276351
Balech, B., Brennan, L., Carrillo de Santa Pau, E., Cavalieri, D., Coort, S., D’Elia, D., Dragsted, L. O., Eftimov, T., Evelo, C. T., Ferk, P., Finglas, P., Gori, A., Hancock, J., Kalaš, M., Koroušić Seljak, B., Lachat, C., Leskošek, B., Pasolli, E., Pesole, G., … Bouwman, J. (2022). The future of food and nutrition in ELIXIR. F1000Research, 11, 978. https://doi.org/10.12688/f1000research.51747.1
Lacruz-Pleguezuelos, B., Fernández, L. P., Ramírez de Molina, A., Carrillo de Santa Pau, E., & Marcos-Zambrano, L. J. (2022). Bioinformatic methods for stratification of obese patients and identification of cancer susceptibility biomarkers based on the analysis of the gut microbiome. https://doi.org/10.1101/2022.11.17.516892
Jodkowska, K., Pancaldi, V., Rigau, M., Almeida, R., Fernández-Justel, J. M., Graña-Castro, O., Rodríguez-Acebes, S., Rubio-Camarillo, M., Carrillo-de Santa Pau, E., Pisano, D., Al-Shahrour, F., Valencia, A., Gómez, M., & Méndez, J. (2022). 3D chromatin connectivity underlies replication origin efficiency in mouse embryonic stem cells. Nucleic Acids Research, 50(21), 12149–12165. https://doi.org/10.1093/nar/gkac1111
Johansson, P., Laguna, T., Ossowski, J., Pancaldi, V., Brauser, M., Dührsen, U., Keuneke, L., Queiros, A., Richter, J., Martín-Subero, J. I., Siebert, R., Schlegelberger, B., Küppers, R., Dürig, J., Murga Penas, E. M., Carillo-de Santa Pau, E., & Bergmann, A. K. (2022). Epigenome-wide analysis of T-cell large granular lymphocytic leukemia identifies BCL11B as a potential biomarker. Clinical Epigenetics, 14(1). https://doi.org/10.1186/s13148-022-01362-z
Marcos-Zambrano, L. J., Karaduzovic-Hadziabdic, K., Loncar Turukalo, T., Przymus, P., Trajkovik, V., Aasmets, O., Berland, M., Gruca, A., Hasic, J., Hron, K., Klammsteiner, T., Kolev, M., Lahti, L., Lopes, M. B., Moreno, V., Naskinova, I., Org, E., Paciência, I., Papoutsoglou, G., … Truu, J. (2021). Applications of Machine Learning in Human Microbiome Studies: A Review on Feature Selection, Biomarker Identification, Disease Prediction and Treatment. Frontiers in Microbiology, 12. https://doi.org/10.3389/fmicb.2021.634511
Moreno-Indias, I., Lahti, L., Nedyalkova, M., Elbere, I., Roshchupkin, G., Adilovic, M., Aydemir, O., Bakir-Gungor, B., Santa Pau, E. C., D’Elia, D., Desai, M. S., Falquet, L., Gundogdu, A., Hron, K., Klammsteiner, T., Lopes, M. B., Marcos-Zambrano, L. J., Marques, C., Mason, M., … Claesson, M. J. (2021). Statistical and Machine Learning Techniques in Human Microbiome Studies: Contemporary Challenges and Solutions. Frontiers in Microbiology, 12. https://doi.org/10.3389/fmicb.2021.635781
Milton-Laskibar, I., Marcos-Zambrano, L. J., Gómez-Zorita, S., Fernández-Quintela, A., Carrillo de Santa Pau, E., Martínez, J. A., & Portillo, M. P. (2021). Gut Microbiota Induced by Pterostilbene and Resveratrol in High-Fat-High-Fructose Fed Rats: Putative Role in Steatohepatitis Onset. Nutrients, 13(5), 1738. https://doi.org/10.3390/nu13051738
Hübschmann, D., Kleinheinz, K., Wagener, R., Bernhart, S. H., López, C., Toprak, U. H., Sungalee, S., Ishaque, N., Kretzmer, H., Kreuz, M., Waszak, S. M., Paramasivam, N., Ammerpohl, O., Aukema, S. M., Beekman, R., Bergmann, A. K., Bieg, M., Binder, H., Borkhardt, A., … Siebert, R. (2021). Mutational mechanisms shaping the coding and noncoding genome of germinal center derived B-cell lymphomas. Leukemia, 35(7), 2002–2016. https://doi.org/10.1038/s41375-021-01251-z
Boer, J. M., Valsecchi, M. G., Hormann, F. M., Antić, Ž., Zaliova, M., Schwab, C., Cazzaniga, G., Arfeuille, C., Cavé, H., Attarbaschi, A., Strehl, S., Escherich, G., Imamura, T., Ohki, K., Grüber, T. A., Sutton, R., Pastorczak, A., Lammens, T., Lambert, F., … Pieters, R. (2021). Favorable outcome of NUTM1-rearranged infant and pediatric B cell precursor acute lymphoblastic leukemia in a collaborative international study. Leukemia, 35(10), 2978–2982. https://doi.org/10.1038/s41375-021-01333-y
Salinero-Fort, M. A., Andrés-Rebollo, F. J. S., Cárdenas-Valladolid, J., Méndez-Bailón, M., Chico-Moraleja, R. M., de Santa Pau, E. C., Jiménez-Trujillo, I., Gómez-Campelo, I., de Burgos Lunar, C., de Miguel-Yanes, J. M., Abanades-Herranz, J. C., Vicente-Tutor, A. M. S., Sanz-Pascual, M., Arnalte-Barrera, M., Pulido-Fernández, S., Donaire-Jiménez, E. M., Montero-Lizana, C., Domínguez-Paniagua, M., … Zazo-Lázaro, M. P. (2021). Cardiovascular risk factors associated with acute myocardial infarction and stroke in the MADIABETES cohort. Scientific Reports, 11(1). https://doi.org/10.1038/s41598-021-94121-8
Arcila, J., Loria-Kohen, V., Ramírez de Molina, A., Carrillo de Santa Pau, E., & Marcos-Zambrano, L. J. (2021). Metataxonomic review to elucidate the role of the microbiome in Celiac disease across the gastrointestinal tract. https://doi.org/10.1101/2021.08.08.455560
Chouvarine, P., Antić, Ž., Lentes, J., Schröder, C., Alten, J., Brüggemann, M., Carrillo-de Santa Pau, E., Illig, T., Laguna, T., Schewe, D., Stanulla, M., Tang, M., Zimmermann, M., Schrappe, M., Schlegelberger, B., Cario, G., & Bergmann, A. K. (2021). Transcriptional and Mutational Profiling of B-Other Acute Lymphoblastic Leukemia for Improved Diagnostics. Cancers, 13(22), 5653. https://doi.org/10.3390/cancers13225653
Marqués, M., Tranchant, R., Risa-Ebrí, B., Suárez-Solís, M. L., Fernández, L. C., Carrillo-de-Santa-Pau, E., del Pozo, N., Martínez de Villarreal, J., Meiller, C., Allory, Y., Blum, Y., Pirker, C., Hegedus, B., Barry, S. T., Carnero, A., Berger, W., Jean, D., & Real, F. X. (2020). Combined MEK and PI3K/p110β Inhibition as a Novel Targeted Therapy for Malignant Mesothelioma Displaying Sarcomatoid Features. Cancer Research, 80(4), 843–856. https://doi.org/10.1158/0008-5472.can-19-1633
Richart, L., Lapi, E., Pancaldi, V., Cuenca, M., Carrillo-de-Santa Pau, E., Madrid-Mencía, M., Neyret-Kahn, H., Radvanyi, F., Rodríguez, J. A., Cuartero, Y., Serra, F., Le Dily, F., Valencia, A., Marti-Renom, M. A., & Real, F. X. (2020). STAG2 loss-of-function affects short-range genomic contacts and modulates urothelial differentiation in bladder cancer cells. https://doi.org/10.1101/2020.08.06.240457
Jodkowska, K., Pancaldi, V., Almeida, R., Rigau, M., Graña-Castro, O., Fernández-Justel, J. M., Rodríguez-Acebes, S., Rubio-Camarillo, M., Carrillo-de Santa Pau, E., Pisano, D., Al-Shahrour, F., Valencia, A., Gómez, M., & Méndez, J. (2019). Three-dimensional connectivity and chromatin environment mediate the activation efficiency of mammalian DNA replication origins. https://doi.org/10.1101/644971
Cobo, I., Martinelli, P., Flández, M., Bakiri, L., Zhang, M., Carrillo-de-Santa-Pau, E., Jia, J., Sánchez-Arévalo Lobo, V. J., Megías, D., Felipe, I., del Pozo, N., Millán, I., Thommesen, L., Bruland, T., Olson, S. H., Smith, J., Schoonjans, K., Bamlet, W. R., Petersen, G. M., … Real, F. X. (2018). Transcriptional regulation by NR5A2 links differentiation and inflammation in the pancreas. Nature, 554(7693), 533–537. https://doi.org/10.1038/nature25751
Salinero-Fort, M. A., Gómez-Campelo, P., San Andrés-Rebollo, F. J., Cárdenas-Valladolid, J., Abánades-Herranz, J. C., Carrillo de Santa Pau, E., Chico-Moraleja, R. M., Beamud-Victoria, D., de Miguel-Yanes, J. M., Jimenez-Garcia, R., López-de-Andres, A., Ramallo-Fariña, Y., & De Burgos-Lunar, C. (2018). Prevalence of depression in patients with type 2 diabetes mellitus in Spain (the DIADEMA Study) : results from the MADIABETES cohort. BMJ Open, 8(9), e020768. https://doi.org/10.1136/bmjopen-2017-020768
Grassi, L., Pourfarzad, F., Ullrich, S., Merkel, A., Were, F., Carrillo-de-Santa-Pau, E., Yi, G., Hiemstra, I. H., Tool, A. T. J., Mul, E., Perner, J., Janssen-Megens, E., Berentsen, K., Kerstens, H., Habibi, E., Gut, M., Yaspo, M. L., Linser, M., Lowy, E., … Kuijpers, T. W. (2018). Dynamics of Transcription Regulation in Human Bone Marrow Myeloid Differentiation to Mature Blood Neutrophils. Cell Reports, 24(10), 2784–2794. https://doi.org/10.1016/j.celrep.2018.08.018
Bergmann, A. K., Fataccioli, V., Castellano, G., Martin-Garcia, N., Pelletier, L., Ammerpohl, O., Bergmann, J., Bhat, J., Pau, E. C. S., Martín-Subero, J. I., Moffitt, A. B., Valencia, A., Oberg, H.-H., Wesch, D., Jayne, S., Dyer, M. J. S., Kabelitz, D., Gaulard, P., & Siebert, R. (2018). DNA methylation profiling of hepatosplenic T-cell lymphoma. Haematologica, 104(3), e104–e107. https://doi.org/10.3324/haematol.2018.196196
Campos-Sanchez, E., Deleyto-Seldas, N., Dominguez, V., Carrillo-de-Santa-Pau, E., Ura, K., Rocha, P. P., Kim, J., Aljoufi, A., Esteve-Codina, A., Dabad, M., Gut, M., Heyn, H., Kaneda, Y., Nimura, K., Skok, J. A., Martinez-Frias, M. L., & Cobaleda, C. (2017). Wolf-Hirschhorn Syndrome Candidate 1 Is Necessary for Correct Hematopoietic and B Cell Development. Cell Reports, 19(8), 1586–1601. https://doi.org/10.1016/j.celrep.2017.04.069
Ecker, S., Chen, L., Pancaldi, V., Bagger, F. O., Fernández, J. M., Carrillo de Santa Pau, E., Juan, D., Mann, A. L., Watt, S., Casale, F. P., Sidiropoulos, N., Rapin, N., Merkel, A., Stunnenberg, H. G., Stegle, O., Frontini, M., Downes, K., Pastinen, T., … Paul, D. S. (2017). Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types. Genome Biology, 18(1). https://doi.org/10.1186/s13059-017-1156-8
Sánchez-Arévalo Lobo, V. J., Fernández, L. C., Carrillo-de-Santa-Pau, E., Richart, L., Cobo, I., Cendrowski, J., Moreno, U., del Pozo, N., Megías, D., Bréant, B., Wright, C. V., Magnuson, M., & Real, F. X. (2017). c-Myc downregulation is required for preacinar to acinar maturation and pancreatic homeostasis. Gut, gutjnl-2016-312306. https://doi.org/10.1136/gutjnl-2016-312306
Stunnenberg, H. G., Hirst, M., Abrignani, S., Adams, D., de Almeida, M., Altucci, L., Amin, V., Amit, I., Antonarakis, S. E., Aparicio, S., Arima, T., Arrigoni, L., Arts, R., Asnafi, V., Esteller, M., Bae, J.-B., Bassler, K., Beck, S., Berkman, B., … Zipprich, G. (2016). The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery. Cell, 167(5), 1145–1149. https://doi.org/10.1016/j.cell.2016.11.007
Fernández, J. M., de la Torre, V., Richardson, D., Royo, R., Puiggròs, M., Moncunill, V., Fragkogianni, S., Clarke, L., Flicek, P., Rico, D., Torrents, D., Carrillo de Santa Pau, E., & Valencia, A. (2016). The BLUEPRINT Data Analysis Portal. Cell Systems, 3(5), 491-495.e5. https://doi.org/10.1016/j.cels.2016.10.021
Astle, W. J., Elding, H., Jiang, T., Allen, D., Ruklisa, D., Mann, A. L., Mead, D., Bouman, H., Riveros-Mckay, F., Kostadima, M. A., Lambourne, J. J., Sivapalaratnam, S., Downes, K., Kundu, K., Bomba, L., Berentsen, K., Bradley, J. R., Daugherty, L. C., Delaneau, O., … Soranzo, N. (2016). The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. Cell, 167(5), 1415-1429.e19. https://doi.org/10.1016/j.cell.2016.10.042
Toll, A., Fernández, L. C., Pons, T., Groesser, L., Sagrera, A., Carrillo-de Santa Pau, E., Vicente, A., Baselga, E., Vázquez, M., Beltrán, S., Pisano, D. G., Rueda, D., Gut, M., Pujol, R. M., Hafner, C., Gut, I., Valencia, A., & Real, F. X. (2016). Somatic Embryonic FGFR2 Mutations in Keratinocytic Epidermal Nevi. Journal of Investigative Dermatology, 136(8), 1718–1721. https://doi.org/10.1016/j.jid.2016.03.040
Varier, R. A., de Santa Pau, E. C., van der Groep, P., Lindeboom, R. G. H., Matarese, F., Mensinga, A., Smits, A. H., Edupuganti, R. R., Baltissen, M. P., Jansen, P. W. T. C., ter Hoeve, N., van Weely, D. R., Poser, I., van Diest, P. J., Stunnenberg, H. G., & Vermeulen, M. (2016). Recruitment of the Mammalian Histone-modifying EMSY Complex to Target Genes Is Regulated by ZNF131. Journal of Biological Chemistry, 291(14), 7313–7324. https://doi.org/10.1074/jbc.m115.701227
Pancaldi, V., Carrillo-de-Santa-Pau, E., Javierre, B. M., Juan, D., Fraser, P., Spivakov, M., Valencia, A., & Rico, D. (2016). Integrating epigenomic data and 3D genomic structure with a new measure of chromatin assortativity. Genome Biology, 17(1). https://doi.org/10.1186/s13059-016-1003-3
Earl, J., Rico, D., Carrillo-de-Santa-Pau, E., Rodríguez-Santiago, B., Méndez-Pertuz, M., Auer, H., Gómez, G., Grossman, H. B., Pisano, D. G., Schulz, W. A., Pérez-Jurado, L. A., Carrato, A., Theodorescu, D., Chanock, S., Valencia, A., & Real, F. X. (2016). Erratum to: The UBC-40 Urothelial Bladder Cancer cell line index: a genomic resource for functional studies. BMC Genomics, 17(1). https://doi.org/10.1186/s12864-016-3179-z
Juan, D., Perner, J., Carrillo de Santa Pau, E., Marsili, S., Ochoa, D., Chung, H.-R., Vingron, M., Rico, D., & Valencia, A. (2016). Epigenomic Co-localization and Co-evolution Reveal a Key Role for 5hmC as a Communication Hub in the Chromatin Network of ESCs. Cell Reports, 14(5), 1246–1257. https://doi.org/10.1016/j.celrep.2016.01.008
Mazarico, J. M., Sánchez-Arévalo Lobo, V. J., Favicchio, R., Greenhalf, W., Costello, E., Carrillo-de Santa Pau, E., Marqués, M., Lacal, J. C., Aboagye, E., & Real, F. X. (2016). Choline Kinase Alpha (CHKα) as a Therapeutic Target in Pancreatic Ductal Adenocarcinoma: Expression, Predictive Value, and Sensitivity to Inhibitors. Molecular Cancer Therapeutics, 15(2), 323–333. https://doi.org/10.1158/1535-7163.mct-15-0214
Salinero-Fort, M. Á., San Andrés-Rebollo, F. J., de Burgos-Lunar, C., Abánades-Herranz, J. C., Carrillo-de-Santa-Pau, E., Chico-Moraleja, R. M., Jiménez-García, R., López-de-Andrés, A., & Gómez-Campelo, P. (2016). Cardiovascular and all-cause mortality in patients with type 2 diabetes mellitus in the MADIABETES Cohort Study: Association with chronic kidney disease. Journal of Diabetes and Its Complications, 30(2), 227–236. https://doi.org/10.1016/j.jdiacomp.2015.10.007
Galindo-Albarrán, A. O., López-Portales, O. H., Gutiérrez-Reyna, D. Y., Rodríguez-Jorge, O., Sánchez-Villanueva, J. A., Ramírez-Pliego, O., Bergon, A., Loriod, B., Holota, H., Imbert, J., Hernández-Mendoza, A., Ferrier, P., Carrillo-de Santa Pau, E., Valencia, A., Spicuglia, S., & Santana, M. A. (2016). CD8 + T Cells from Human Neonates Are Biased toward an Innate Immune Response. Cell Reports, 17(8), 2151–2160. https://doi.org/10.1016/j.celrep.2016.10.056
Richart, L., Carrillo-de Santa Pau, E., Río-Machín, A., de Andrés, M. P., Cigudosa, J. C., Lobo, V. J. S.-A., & Real, F. X. (2016). BPTF is required for c-MYC transcriptional activity and in vivo tumorigenesis. Nature Communications, 7(1). https://doi.org/10.1038/ncomms10153
Carrillo-de-Santa-Pau, E., Juan, D., Pancaldi, V., Were, F., Martin-Subero, I., Rico, D., & Valencia, A. (2016). Automatic identification of informative regions with epigenomic changes associated to hematopoiesis. https://doi.org/10.1101/082917
Martinelli, P., Carrillo-de Santa Pau, E., Cox, T., Sainz, B., Dusetti, N., Greenhalf, W., Rinaldi, L., Costello, E., Ghaneh, P., Malats, N., Büchler, M., Pajic, M., Biankin, A. V., Iovanna, J., Neoptolemos, J., & Real, F. X. (2016). GATA6 regulates EMT and tumour dissemination, and is a marker of response to adjuvant chemotherapy in pancreatic cancer. Gut, 66(9), 1665–1676. https://doi.org/10.1136/gutjnl-2015-311256
Earl, J., Rico, D., Carrillo-de-Santa-Pau, E., Rodríguez-Santiago, B., Méndez-Pertuz, M., Auer, H., Gómez, G., Grossman, H. B., Pisano, D. G., Schulz, W. A., Pérez-Jurado, L. A., Carrato, A., Theodorescu, D., Chanock, S., Valencia, A., & Real, F. X. (2015). The UBC-40 Urothelial Bladder Cancer cell line index: a genomic resource for functional studies. BMC Genomics, 16(1). https://doi.org/10.1186/s12864-015-1450-3
Ezkurdia, I., Rodriguez, J. M., Carrillo-de Santa Pau, E., Vázquez, J., Valencia, A., & Tress, M. L. (2015). Most Highly Expressed Protein-Coding Genes Have a Single Dominant Isoform. Journal of Proteome Research, 14(4), 1880–1887. https://doi.org/10.1021/pr501286b
Salinero-Fort, M. A., San Andrés-Rebollo, F. J., de Burgos-Lunar, C., Gómez-Campelo, P., Chico-Moraleja, R. M., López de Andrés, A., & Jiménez-García, R. (2015). Five-Year Incidence of Chronic Kidney Disease (Stage 3-5) and Associated Risk Factors in a Spanish Cohort: The MADIABETES Study. PLOS ONE, 10(4), e0122030. https://doi.org/10.1371/journal.pone.0122030
Earl, J., Rico, D., Carrillo-de-Santa-Pau, E., Rodríguez-Santiago, B., Méndez-Pertuz, M., Auer, H., Gómez, G., Grossman, H. B., Pisano, D. G., Schulz, W. A., Pérez-Jurado, L. A., Carrato, A., Theodorescu, D., Chanock, S., Valencia, A., & Real, F. X. (2015). Erratum to: The UBC-40 Urothelial Bladder Cancer Cell Line Index: a genomic resource for functional studies. BMC Genomics, 16(1). https://doi.org/10.1186/s12864-015-2227-4
Kretzmer, H., Bernhart, S. H., Wang, W., Haake, A., Weniger, M. A., Bergmann, A. K., Betts, M. J., Carrillo-de-Santa-Pau, E., Doose, G., Gutwein, J., Richter, J., Hovestadt, V., Huang, B., Rico, D., Jühling, F., Kolarova, J., Lu, Q., … Radlwimmer, B. (2015). DNA methylome analysis in Burkitt and follicular lymphomas identifies differentially methylated regions linked to somatic mutation and transcriptional control. Nature Genetics, 47(11), 1316–1325. https://doi.org/10.1038/ng.3413
Martinelli, P., Madriles, F., Cañamero, M., Pau, E. C. S., Pozo, N. del, Guerra, C., & Real, F. X. (2015). The acinar regulator Gata6 suppressesKrasG12V-driven pancreatic tumorigenesis in mice. Gut, 65(3), 476–486. https://doi.org/10.1136/gutjnl-2014-308042
Barbáchano, A., Fernández-Barral, A., Pereira, F., Segura, M. F., Ordóñez-Morán, P., Carrillo-de Santa Pau, E., González-Sancho, J. M., Hanniford, D., Martínez, N., Costales-Carrera, A., Real, F. X., Pálmer, H. G., Rojas, J. M., Hernando, E., & Muñoz, A. (2015). SPROUTY-2 represses the epithelial phenotype of colon carcinoma cells via upregulation of ZEB1 mediated by ETS1 and miR-200/miR-150. Oncogene, 35(23), 2991–3003. https://doi.org/10.1038/onc.2015.366
Allory, Y., Beukers, W., Sagrera, A., Flández, M., Marqués, M., Márquez, M., van der Keur, K. A., Dyrskjot, L., Lurkin, I., Vermeij, M., Carrato, A., Lloreta, J., Lorente, J. A., Carrillo-de Santa Pau, E., Masius, R. G., Kogevinas, M., Steyerberg, E. W., van Tilborg, A. A. G., Abas, C., … Real, F. X. (2014). Telomerase Reverse Transcriptase Promoter Mutations in Bladder Cancer: High Frequency Across Stages, Detection in Urine, and Lack of Association with Outcome. European Urology, 65(2), 360–366. https://doi.org/10.1016/j.eururo.2013.08.052
Santa Pau, E. C., Real, F. X., & Valencia, A. (2014). Bioinformatics Analysis of Pancreas Cancer Genome in High-Throughput Genomic Technologies. Molecular Diagnostics and Treatment of Pancreatic Cancer, 93–131. https://doi.org/10.1016/b978-0-12-408103-1.00005-4
Balbás-Martínez, C., Sagrera, A., Carrillo-de-Santa-Pau, E., Earl, J., Márquez, M., Vazquez, M., Lapi, E., Castro-Giner, F., Beltran, S., Bayés, M., Carrato, A., Cigudosa, J. C., Domínguez, O., Gut, M., Herranz, J., Juanpere, N., Kogevinas, M., Langa, X., López-Knowles, E., … Real, F. X. (2013). Recurrent inactivation of STAG2 in bladder cancer is not associated with aneuploidy. Nature Genetics, 45(12), 1464–1469. https://doi.org/10.1038/ng.2799
Liu, X., Gomez-Pinillos, A., Loder, C., Carrillo-de Santa Pau, E., Qiao, R., Unger, P. D., Kurek, R., Oddoux, C., Melamed, J., Gallagher, R. E., Mandeli, J., & Ferrari, A. C. (2012). KLF6 Loss of Function in Human Prostate Cancer Progression Is Implicated in Resistance to Androgen Deprivation. The American Journal of Pathology, 181(3), 1007–1016. https://doi.org/10.1016/j.ajpath.2012.06.008
Ruiz-Llorente, S., de Pau, E. C. S., Sastre-Perona, A., Montero-Conde, C., Gómez-López, G., Fagin, J. A., Valencia, A., Pisano, D. G., & Santisteban, P. (2012). Genome-wide analysis of Pax8 binding provides new insights into thyroid functions. BMC Genomics, 13(1). https://doi.org/10.1186/1471-2164-13-147
Martín-Madrazo, C., Soto-Díaz, S., Cañada-Dorado, A., Salinero-Fort, M. A., Medina-Fernández, M., de Santa Pau, E. C., Gómez-Campelo, P., & Abánades-Herranz, J. C. (2012). Cluster Randomized Trial to Evaluate the Effect of a Multimodal Hand Hygiene Improvement Strategy in Primary Care. Infection Control & Hospital Epidemiology, 33(7), 681–688. https://doi.org/10.1086/666343
Jancura, P., Mavridou, E., Carrillo-de Santa Pau, E., & Marchiori, E. (2012). A methodology for detecting the orthology signal in a PPI network at a functional complex level. BMC Bioinformatics, 13(S10). https://doi.org/10.1186/1471-2105-13-s10-s18
Martín-Madrazo, C., Salinero-Fort, M. Á., Cañada-Dorado, A., Carrillo-De Santa-Pau, E., Soto-Díaz, S., & Abánades-Herranz, J. C. (2011). Evaluación del cumplimiento de higiene de las manos en un área de atención primaria de Madrid. Enfermedades Infecciosas y Microbiología Clínica, 29(1), 32–35. https://doi.org/10.1016/j.eimc.2010.03.009
Arrieta, F., Salinero, M., Piñera, M., Botella-Carretero, J. I., Iglesias, P., Abanades, J. C., Carrillo, E., Nogales, P., Balsa, J. A., Zamarrón, I., Rovira, A., & Vázquez, C. (2011). Estudio descriptivo de la evolución clínico-asistencial de la población con diabetes tipo 2 en la Comunidad de Madrid. Estudio de seguimiento diabético tipo 2 (ESD-2). Avances En Diabetología, 27(2), 53–60. https://doi.org/10.1016/s1134-3230(11)70009-6
Matarese, F., Carrillo‐de Santa Pau, E., & Stunnenberg, H. G. (2011). 5‐Hydroxymethylcytosine: a new kid on the epigenetic block? Molecular Systems Biology, 7(1). Portico. https://doi.org/10.1038/msb.2011.95
Pau, E. C. S., Arias, F. C., Pelaez, E. C., Trueba, I. M., Hernández, I. S., Molina, G. M. M., Balsalobre, R. M., López, S. S., Gómez-Pinillos, A., & Toledo Lobo, M. del V. (2010). Vascular Endothelial Growth Factor (VEGF) Serum Levels Are Associated With Survival in Early Stages of Lung Cancer Patients. Cancer Investigation, 28(4), 393–398. https://doi.org/10.1080/07357900903405900
Cárdenas-Valladolid, J., Martín-Madrazo, C., Salinero-Fort, M. A., de-Santa Pau, E. C., Abánades-Herranz, J. C., & de Burgos-Lunar, C. (2010). Prevalence of Adherence to Treatment in Homebound Elderly People in Primary Health Care. Drugs & Aging, 27(8), 641–651. https://doi.org/10.2165/11537320-000000000-00000
Salinero-Fort, M. A., Carrillo-de Santa Pau, E., Abánades-Herranz, J. C., Dujovne-Kohan, I., & Cárdenas-Valladolid, J. (2010). Riesgo basal de Diabetes Mellitus en Atención Primaria según cuestionario FINDRISC, factores asociados y evolución clínica tras 18 meses de seguimiento. Revista Clínica Española, 210(9), 448–453. https://doi.org/10.1016/j.rce.2010.03.008
Fe de errores. (2009). Revista Clínica Española, 209(9), 423. https://doi.org/10.1016/s0014-2565(09)72526-3
Carrillo de Santa Pau, E., Arias, F. C., Caso Peláez, E., Muñoz Molina, G. M., Sánchez Hernández, I., Muguruza Trueba, I., Moreno Balsalobre, R., Sacristán López, S., Gómez Pinillos, A., & del Val Toledo Lobo, M. (2009). Prognostic significance of the expression of vascular endothelial growth factors A, B, C, and D and their receptors R1, R2, and R3 in patients with nonsmall cell lung cancer. Cancer, 115(8), 1701–1712. Portico. https://doi.org/10.1002/cncr.24193
Carrillo de Santa Pau, E., Paniagua Carral, B., Salinero Fort, M. Á., & Abánades Herranz, J. C. (2009). Factores asociados a la vacunación de la gripe en individuos mayores de 60 años atendidos en Atención Primaria. Revista Clínica Española, 209(4), 180–184. https://doi.org/10.1016/s0014-2565(09)71311-6
Martín-Madrazo, C., Cañada-Dorado, A., Salinero- Fort, M. A., Abanades-Herranz, J. C., Arnal-Selfa, R., García-Ferradal, I., Espejo-Matorral, F., Santa-Pau, E. C., & Soto-Diaz, S. (2009). Effectiveness of a training programme to improve hand hygiene compliance in primary healthcare. BMC Public Health, 9(1). https://doi.org/10.1186/1471-2458-9-469
Salinero-Fort, M., Arrieta-Blanco, F., Carrillo-de Santa Pau, E., Martín-Madrazo, C., Piñera-Tames, M., Vázquez-Martínez, C., & Abánades-Herranz, J. C. (2009). Eficacia del modelo PRECEDE, de educación para la salud, en el control metabólico y de los factores de riesgo cardiovascular en pacientes con diabetes mellitus tipo 2. Revista Clínica Española, 209(7), 325–331. https://doi.org/10.1016/s0014-2565(09)71816-8
