research group

Developmental Neurobiology Unit

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Developmental ORIgins of Healthy and Unhealthy AgeiNg: The Role of Maternal Obesity – Introduction to DORIAN

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Developmental Pattern Formation: Spanish Contributions from a Biophysical Perspective

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Developmental regulators FlbE/D orchestrate the polarity site-to-nucleus dynamics of the fungal bZIP transcription factor FlbB

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DFprot: A webtool for predicting local chain deformability

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DGCR8-mediated disruption of miRNA biogenesis induces cellular senescence in primary fibroblasts

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Diborane(4) as a powerful acid–base transformer

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Diet-host-microbe interactions in health and disease

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Dietary fat, the gut microbiota, and metabolic health – a systematic review conducted within the MyNewGut project

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Dietary oils mediate cortisol kinetics and the hepatic mRNA expression profile of stress-responsive genes in gilthead sea bream (Sparus aurata) exposed to crowding stress. Implications on energy homeostasis and stress susceptibility

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Dietary Supplementation with Sugar Beet Fructooligosaccharides and Garlic Residues Promotes Growth of Beneficial Bacteria and Increases Weight Gain in Neonatal Lambs

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Dietary β-glucan stimulate complement and C-reactive protein acute phase responses in common carp (Cyprinus carpio) during an Aeromonas salmonicida infection

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Differences in Behavior During Early Nectarine Infection Among Main Monilinia spp. Causing Brown Rot

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Differences in firing efficiency, chromatin and transcription underlie the developmental plasticity of the Arabidopsis originome

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Differences in firing efficiency, chromatin, and transcription underlie the developmental plasticity of the Arabidopsis DNA replication origins

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Differences in gene expression profiling and biomarkers between histological colorectal carcinoma subsets from the serrated pathway

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Differences in the Loin Tenderness of Iberian Pigs Explained through Dissimilarities in Their Transcriptome Expression Profile

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Different contribution of missense and loss-of-function variants to the genetic structure of familial and sporadic Meniere disease

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Different ecological processes drive the assembly of dominant and rare root-associated bacteria in a promiscuous legume

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Different Effect of Vitamin E or Hydroxytyrosol Supplementation to Sow’s Diet on Oxidative Status and Performances of Weaned Piglets

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Different HCV Exposure Drives Specific miRNA Profile in PBMCs of HIV Patients

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Different Lactobacillus populations dominate in “Chorizo de León” manufacturing performed in different production plants

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Different strategies for controlling pressure during the cooling stage in batch retorts

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Differential contribution of the two major polygalacturonases from Penicillium digitatum to virulence towards citrus fruit

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Differential expression and co-expression reveal cell types relevant to genetic disorder phenotypes

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Differential expression in RNA-seq: A matter of depth

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Differential expression of sarcoplasmic proteins in four heterogeneous ovine skeletal muscles

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Differential Gene Expression in Ovaries of Pregnant Pigs with High and Low Prolificacy Levels and Identification of Candidate Genes for Litter Size

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Differential metabolic and gene expression profile of juvenile common dentex (Dentex dentex L.) and gilthead sea bream (Sparus aurata L.) in relation to redox homeostasis

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Differential Modulation of Quorum Sensing Signaling through QslA in Pseudomonas aeruginosa Strains PAO1 and PA14

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Differential proinflammatory signature in vestibular migraine and meniere disease

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Differential susceptibility to noise of mixed Turing and Hopf modes in a photosensitive chemical medium

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Differential tissue expression of uncoupling proteins in gilthead sea bream (Sparus aurata L): Lessons from UCP1 and UCP3 in fish

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Differential Tomato Transcriptomic Responses Induced by Pepino Mosaic Virus Isolates with Differential Aggressiveness

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Differentiation of live and heat-killed E. coli by microwave impedance spectroscopy

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Differently Regulated Gene-Specific Activity of Enhancers Located at the Boundary of Subtopologically Associated Domains: TCRα Enhancer

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Diffusivity Estimation for Activator–Inhibitor Models: Theory and Application to Intracellular Dynamics of the Actin Cytoskeleton

research line

Digital evolution

Studying evolution in the lab provides valuable insights but is often constrained by long timescales...

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Dimeric structure of the coxsackievirus and adenovirus receptor D1 domain at 1.7 A resolution.

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Dioxides of bicyclic thiadiazines: a new family of smooth muscle relaxants

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Direct and maternal additive effects are not the main determinants of Iberian piglet perinatal mortality

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Direct functional assessment of the composite phenotype through multivariate projection strategies

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Direct interaction between a human digestive protease and the mucoadhesive poly(acrylic acid)

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Direct mapping of nanoscale compositional connectivity on intact cell membranes

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Discovering gene expression patterns in time course microarray experiments by ANOVA-SCA

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Discovering molecular functions significantly related to phenotypes by combining gene expression data and biological information

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Discovering semantic features in the literature: A foundation for building functional associations

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Discovery and Transcriptional Profiling of Penicillium digitatum Genes That Could Promote Fungal Virulence during Citrus Fruit Infection

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Discovery of a brain penetrant SGK1 inhibitor using a ligand- and structure-based virtual screening methodology

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Discovery of a proteolytic flagellin family in diverse bacterial phyla that assembles enzymatically active flagella

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Discovery of Mitophagy Inhibitors with Therapeutic Potential in Different Familial Amyotrophic Lateral Sclerosis Mutations

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Discovery of nonnucleoside inhibitors of polymerase from infectious pancreatic necrosis virus (IPNV)

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Discovery of novel Schistosoma mansoni PDE4A inhibitors as potential agents against schistosomiasis

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Discovery of Sphingosine-1-Phosphate Receptor Modulators as Potential CHI3L1 Inhibitors by Ligand-Based Virtual Screening and Molecular Dynamics Simulations

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Discovery of Thiophene Derivatives as Potent, Orally Bioavailable, and Blood–Brain Barrier-Permeable Ebola Virus Entry Inhibitors

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Discrepancies between recombination frequencies and physical distances in Aspergillus nidulans: Implications for gene identification

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Discretization-dependent model for weakly connected excitable media

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Discriminating physiological from non‐physiological interfaces in structures of protein complexes: A community‐wide study

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Discrimination and selection of new potential antibacterial compounds using simple topological descriptors

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Disease-specific biases in alternative splicing and tissue-specific dysregulation revealed by multitissue profiling of lymphocyte gene expression in type 1 diabetes

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Disentangling drivers of power line use by vultures: Potential to reduce electrocutions

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Disentangling protein metabolic costs in human cells and tissues

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Disentangling Two QTL on Porcine Chromosome 12 for Backfat Fatty Acid Composition

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Dispersion, Rehybridization, and Pentacoordination: Keys to Understand Clustering of Boron and Aluminum Hydrides and Halides

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Disrupting bonding in azoles through beryllium bonds: Unexpected coordination patterns and acidity enhancement

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Disruption of the mitochondrial network in a mouse model of Huntington’s disease visualized by in-tissue multiscale 3D electron microscopy

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Dissecting Cytophagalysin: Structural and Biochemical Studies of a Bacterial Pappalysin-Family Metallopeptidase

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Dissecting structural and nucleotide genome-wide variation in inbred Iberian pigs

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Dissecting the expression patterns of transcription factors across conditions using an integrated network-based approach

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Dissecting Tissue-Specific Transcriptomic Responses from Leaf and Roots under Salt Stress in Petunia hybrida Mitchell

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Dissection and prediction of RNA-binding sites on proteins

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Dissipative systems: From physics to robust nonlinear control

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Distilling identifiable and interpretable dynamic models from biological data

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Distilling Robust Design Principles of Biocircuits Using Mixed Integer Dynamic Optimization

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Distinct GSDMB protein isoforms and protease cleavage processes differentially control pyroptotic cell death and mitochondrial damage in cancer cells

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Distinct light-mediated pathways regulate the biosynthesis and exchange of isoprenoid precursors during Arabidopsis seedling development

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Distinct phenotype of hepatotoxicity associated with illicit use of anabolic androgenic steroids

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Distribution and depletion of sulfadiazine after a multiple per os dosing in gilthead sea bream (Sparus aurata) fed two different diets

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Distribution of DNA-condensing protein complexes in the adenovirus core

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Distribution of the uncultured protist MAST-4 in the Indian Ocean, Drake Passage and Mediterranean Sea assessed by real-time quantitative PCR

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Distribution of y chromosomal STRs loci in Mayan and Mestizo populations from Guatemala

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Divergent Substrate-Binding Mechanisms Reveal an Evolutionary Specialization of Eukaryotic Prefoldin Compared to Its Archaeal Counterpart

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Diverging co-translational protein complex assembly pathways are governed by interface energy distribution

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Diverse regulation of the CreA carbon catabolite repressor in aspergillus nidulans

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Diversification and biodiversity dynamics of hot and cold spots

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Diversity across major and candidate genes in European local pig breeds

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Diversity and distribution of unicellular opisthokonts along the European coast analysed using high-throughput sequencing

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Diversity and metabolism of Woeseiales bacteria, global members of marine sediment communities

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Diversity and physiology of polyhydroxyalkanoate-producing and-degrading strains in microbial mats

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Diversity of gene expression responses to light quality in barley

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Diversity of mechanisms to control bacterial GTP homeostasis by the mutually exclusive binding of adenine and guanine nucleotides to IMP dehydrogenase

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Diversity of Quaternary Structures Regulates Nuclear Receptor Activities.

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Diversity of Rainbow Trout Blood B Cells Revealed by Single Cell RNA Sequencing

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Diversity Patterns from Ecological Models at Dynamical Equilibrium

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DLG4-related synaptopathy: a new rare brain disorder

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DNA binding properties and antileukemic (L1210) activity of a Pt-pentamidine complex

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DNA methylation profiling of hepatosplenic t-cell lymphoma

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DNA Methylation Signature in Mononuclear Cells and Proinflammatory Cytokines May Define Molecular Subtypes in Sporadic Meniere Disease

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DNA methylome analysis in Burkitt and follicular lymphomas identifies differentially methylated regions linked to somatic mutation and transcriptional control

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DnaSP 6: DNA Sequence Polymorphism Analysis of Large Data Sets