Sandra González de la Fuente

Technical Supervisor of the Biocomputational Analysis Core Facility at the Centro de Biología Molecular Severo Ochoa (CBM, CSIC-UAM). Her work includes: advice on the design of massive sequencing experiments taking into account the later computational analysis; computational analysis of massive sequencing data (resequencing, de novo assembly, RNA-seq, ChIP-seq, CLIP-seq, exome sequencing, 16S, 18S and ITS metagenomics, search for variants and SNPs, detection of alternative splicing events, amplicons, etc.); statistical analysis of experimental data (exploratory analysis, hypothesis testing by parametric and non-parametric methods, robust statistical methods, ANOVA, factorial and principal component analysis), mainly with R; data analysis of microarray experiments; comprehensive analysis of data from diverse sources (genomics, biological, medical, data mining); upload of nucleotide sequences, functional annotation and sequencing reads to repositories such as the European Nucleotide Archive (ENA, EMBL-EBI); programmatic management of genome databases such as Ensembl, GenBank or FlyBase; implementation, maintenance and updating of the Service's own pipelines for massive sequencing data analysis; and development of specialised software on demand in Bash, Tcsh, Python and R, including the computational development of nanopore sequencing experiments with the Oxford Nanopore MinION. (Description curated from publicly available data.)