Marta Alonso Fernández-Pacheco
Biography
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Chief Researcher at NEIKER (Basque Institute for Agricultural Research and Development), in the Animal Science research group. PhD from the Universidad Autónoma de Madrid (1998) with the thesis "Coinfecciones víricas producidas por rhabdovirus-birnavirus en salmónidos", supervised by Dr. S. Rodríguez Saint-Jean. Her work on genetic markers to evaluate and improve susceptibility, resistance and tolerance to paratuberculosis in cattle breeding programmes led to the operational group GO_INMUNOGEN, and she has supervised doctoral theses at the Universidad del País Vasco (UPV/EHU) on the early diagnosis of, genomic resistance to and host response against bovine paratuberculosis. Author of 65 scientific articles and inventor of a patent on an in vitro method for the diagnosis of subjects infected by mycobacteria species (2021). (Description curated from publicly available data.) |
Profile
| Institution | NEIKER |
| Position | Chief Researcher |
| Home page | https://research.science.eus/investigadores/752171/detalle |
| Contact email | malonso@neiker.eus |
| ORCID | 0000-0001-5979-347X |
BCB Hub
| BCB Committee | Not a member |
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Research
Research topics
None
Research lines
Projects, networks, transfer & teaching
Industry & knowledge transfer
Patents
- In vitro method for the diagnosis of subjects infected by mycobacteria species ("Método in vitro para el diagnóstico de sujetos infectados por especies de micobacterias", 2021)
Teaching
Master programs
- Master in Microbiology and Health - Universidad del País Vasco (UPV/EHU) (Master's thesis supervisor) - https://www.ehu.eus/es/web/master/master-microbiologia-salud/profesorado-de-tfm?redirect=dameProfesorAjeno&master=317&idPdi=699836
Publications 43 entries
- A High-Throughput and Real-Time Imaging Assay to Quantify <em>Mycobacterium avium</em> Subsp. <em>Paratuberculosis</em> Preprint · 30 Jul 2026
- Early Growth Response Factor 4 (EGR4) Expression in Gut Tissues and Regional Lymph Nodes of Cattle with Different Types of Paratuberculosis-Associated Lesions: Potential Role of EGR4 in Resilience to Paratuberculosis Article · 31 Mar 2025
- Genome-Wide Association Study Reveals Quantitative Trait Loci and Candidate Genes Associated with High Interferon-gamma Production in Holstein Cattle Naturally Infected with Mycobacterium Bovis Article · 3 Jun 2024
- A Genome-Wide Association Study for Tolerance to Paratuberculosis Identifies Candidate Genes Involved in DNA Packaging, DNA Damage Repair, Innate Immunity, and Pathogen Persistence Article · 6 Apr 2022
- Use of ATP-Binding Cassette Subfamily A Member 13 (ABCA13) for Sensitive Detection of Focal Pathological Forms of Subclinical Bovine Paratuberculosis Article · 10 Mar 2022
View all (38 more)
- Identification of loci associated with pathological outcomes in Holstein cattle infected with Mycobacterium avium subsp. paratuberculosis using whole-genome sequence data Article · 11 Oct 2021
- Editorial: Advances in the Diagnosis and Control of Johne's Disease Article · 4 Oct 2021
- Identification of loci associated with susceptibility to Mycobacterium avium subsp. paratuberculosis infection in Holstein cattle using combinations of diagnostic tests and imputed whole-genome sequence data Article · 27 Aug 2021
- Bovine Intelectin 2 Expression as a Biomarker of Paratuberculosis Disease Progression Article · 12 May 2021
- Identification of loci associated with susceptibility to bovine paratuberculosis and with the dysregulation of the MECOM, eEF1A2, and U1 spliceosomal RNA expression Article · 11 Jan 2021
- Detection of latent forms of Mycobacterium avium subsp. paratuberculosis infection using host biomarker-based ELISAs greatly improves paratuberculosis diagnostic sensitivity Article · 3 Sep 2020
- Correlations between single nucleotide polymorphisms in bovine CD209, SLC11A1, SP110 and TLR2 genes and estimated breeding values for several traits in Spanish Holstein cattle Article · Jun 2020
- RNA-Seq analysis of ileocecal valve and peripheral blood from Holstein cattle infected with Mycobacterium avium subsp. paratuberculosis revealed dysregulation of the CXCL8/IL8 signaling pathway Article · 16 Oct 2019
- Deciphering the virulence of Mycobacterium avium subsp. paratuberculosis isolates in animal macrophages using mathematical models Article · May 2019
- Association between combinations of genetic polymorphisms and epidemiopathogenic forms of bovine paratuberculosis Article · Feb 2018
- Mycobacterium avium subsp. paratuberculosis (Map) Fatty Acids Profile Is Strain-Dependent and Changes Upon Host Macrophages Infection Article · 21 Mar 2017
- Increased Lytic Efficiency of Bovine Macrophages Trained with Killed Mycobacteria Article · 7 Nov 2016
- An oral DNA vaccine against infectious haematopoietic necrosis virus (IHNV) encapsulated in alginate microspheres induces dose-dependent immune responses and significant protection in rainbow trout (Oncorrhynchus mykiss) Article · Aug 2015
- Latent infections are the most frequent form of paratuberculosis in slaughtered Friesian cattle Article · 14 Oct 2014
- Mycobacterium Avium subsp. Paratuberculosis Isolates Induce In Vitro Granuloma Formation and Show Successful Survival Phenotype, Common Anti-Inflammatory and Antiapoptotic Responses within Ovine Macrophages Regardless of Genotype or Host of Origin Article · 11 Aug 2014
- Sensitive and Specific Enzyme-Linked Immunosorbent Assay for Detecting Serum Antibodies against Mycobacterium avium subsp. paratuberculosis in Fallow Deer Article · 28 May 2014
- Three-Dimensional In Vitro Models of Granuloma to Study Bacteria-Host Interactions, Drug-Susceptibility, and Resuscitation of Dormant Mycobacteria Article · 2014
- Paratuberculosis Vaccination Causes Only Limited Cross-Reactivity in the Skin Test for Diagnosis of Bovine Tuberculosis Article · 26 Nov 2013
- Mycobacterium avium subspecies paratuberculosis isolates from sheep and goats show reduced persistence in bovine macrophages than cattle, bison, deer and wild boar strains regardless of genotype Article · May 2013
- Licensed DNA Vaccines against Infectious Hematopoietic Necrosis Virus (IHNV) Article · 1 Feb 2013
- Anti-Inflammatory and Antiapoptotic Responses to Infection: A Common Denominator of Human and Bovine Macrophages Infected with Mycobacterium avium Subsp. paratuberculosis Article · 2013
- Quantification of Mycobacterium avium subsp. paratuberculosis Strains Representing Distinct Genotypes and Isolated from Domestic and Wildlife Animal Species by Use of an Automatic Liquid Culture System Article · Aug 2012
- Immunization of adult dairy cattle with a new heat-killed vaccine is associated with longer productive life prior to cows being sent to slaughter with suspected paratuberculosis Article · Feb 2012
- Development of a suicidal DNA vaccine for infectious hematopoietic necrosis virus (IHNV) Article · Mar 2011
- A Mycobacterium avium subsp. paratuberculosis LuxR regulates cell envelope and virulence Article · 26 Aug 2009
- Isolation of Mycobacterium avium subsp. paratuberculosis from Muscle Tissue of Naturally Infected Cattle Article · May 2009
- Significant reduction in bacterial shedding and improvement in milk production in dairy farms after the use of a new inactivated paratuberculosis vaccine in a field trial Article · 2009
- The Mycobacterium avium subsp. paratuberculosis MAP3464 Gene Encodes an Oxidoreductase Involved in Invasion of Bovine Epithelial Cells through the Activation of Host Cell Cdc42 Article · Jan 2008
- The Ability of Mycobacterium avium subsp. paratuberculosis To Enter Bovine Epithelial Cells Is Influenced by Preexposure to a Hyperosmolar Environment and Intracellular Passage in Bovine Mammary Epithelial Cells Article · May 2006
- Inhibition of infectious haematopoietic necrosis virus in cell cultures with peptide‐conjugated morpholino oligomers Article · Jul 2005
- Comparison of two birnavirus-rhabdovirus coinfections in fish cell lines Article · 2005
- The NV Gene of Snakehead Rhabdovirus (SHRV) Is Not Required for Pathogenesis, and a Heterologous Glycoprotein Can Be Incorporated into the SHRV Envelope Article · Jun 2004
- Virulence of Infectious hematopoietic necrosis virus and Infectious pancreatic necrosis virus coinfection in rainbow trout ( Oncorhynchus mykiss ) and nucleotide sequence analysis of the IHNV glycoprotein gene Article · 1 Aug 2003
- A fish specific expression vector containing the interferon regulatory factor 1A (IRF1A) promoter for genetic immunization of fish Article · 2 Apr 2003
- Detection of Infections Pancreatic Necrosis Virus(IPNV) from Leukocytes of Carrier Rainbow Trout Oncorhynchus mykiss. Article · 2001
- Nested PCR improves detection of infectious hematopoietic necrosis virus in cells coinfected with infectious pancreatic necrosis virus Article · Aug 1999
- Viral coinfection in salmonids: infectious pancreatic necrosis virus interferes with infectious hematopoietic necrosis virus Article · Apr 1999
- Vectors for the genetic manipulation of African swine fever virus Article · Jun 1995