José Luis Ruiz Rodríguez
Malaria epigenomics · IPBLN
Biography
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I joined the Bioinformatics and Computational Biology Unit (IPBLN-CSIC) in November 2022, under the competitive call "Technical Personnel for Support" (PTA2021-019864-I). My degree was "Basic and Experimental Biomedicine" (University of Seville, US, 2011-2015), followed by a Bioinformatics specialisation with the MSc "Omics Data Analyses" (University of Vic, UVic-UCC, 2015-2016). During my PhD I performed and integrated multi-omics analyses, with the focus on the epigenomics of the human malaria parasite and the mosquito host, in the doctoral program "Molecular Biology, Biomedicine and Clinical Research" (US, 2016-2022). Overall, I have pursued the profile of a generalist Bioinformatician and Data Scientist, mainly leveraging multi-omics and next-generation sequencing (NGS) datasets of a plethora of organisms, both model and non-model. My current interests include multidisciplinary bioinformatics and up-to-date techniques, such as machine learning, scRNAseq, scATAC-seq, or spatial transcriptomics. I have also developed and currently maintain public software, e.g. a tool for the automatic quantification of dendritic spines (SpineCounter), a pipeline for the assembly and automatic correction of de novo genomes (ILRA), and a pipeline for transcriptomics analyses (reanalyzerGSE). Expert Genome Informatics at the Functional Genomics Center Zurich (FGCZ-ETH/UZH) since March 2025. Note: at the CSIC from December 2016 to February 2025 (Estación Biológica de Doñana and IPBLN). |
Profile
| Institution | IPBLN |
| Position | Technical Staff, Bioinformatics and Computational Biology Unit |
| Home page | https://www.linkedin.com/in/jlrlkdn/ |
| Contact email | joseluis.ruiz@csic.es |
| ORCID | 0000-0003-1901-1888 |
BCB Hub
| BCB Committee | Not a member |
| BCB Tools | reanalyzerGSE, ILRA, SpineCounter |
| BCB Services |
Publications 18 entries
- Probiotic treatment rescues behavioral deficits and gut microbial abnormalities induced by preconceptional stress in mothers and offspring Article · Aug 2026
- Lack of cortistatin drives neuroimmune and vascular dysfunction in brain ischemia Article · 20 Jun 2026
- Influenza A virus NS1 sequesters RNA:DNA hybrids to evade RNase H1-dependent innate immunity Preprint · 7 May 2026
- Human Papillomavirus-Encoded microRNAs as Regulators of Human Gene Expression in Anal Squamous Cell Carcinoma: A Meta-Transcriptomics Study Article · 9 Jun 2025
- The dynamic transcriptome of Plasmodium malariae in the mosquito Preprint · 7 May 2025
View all (13 more)
- Genome drafts of Lotmaria passim strains C2 and C3 isolated from honey bees in Spain Article · 16 Jan 2025
- Alternative splicing and its regulation in the malaria vector Anopheles gambiae Article · 26 Apr 2024
- Cortistatin deficiency reveals a dysfunctional brain endothelium with impaired gene pathways, exacerbated immune activation, and disrupted barrier integrity Article · 4 Oct 2023
- Exploring the Microbiome in Human Reproductive Tract: High-Throughput Methods for the Taxonomic Characterization of Microorganisms Article · Sep 2023
- reanalyzerGSE: tackling the everlasting lack of reproducibility and reanalyses in transcriptomics Preprint · 13 Jul 2023
- From contigs towards chromosomes: automatic improvement of long read assemblies (ILRA) Software · Jul 2023
- The regulatory genome of the malaria vector Anopheles gambiae: integrating chromatin accessibility and gene expression Article · 20 Jan 2021
- Chromatin Structure and Function in Mosquitoes Article · 7 Dec 2020
- Heat Stress Factors Expressed during Seed Maturation Differentially Regulate Seed Longevity and Seedling Greening Article · 6 Mar 2020
- The second life of Plasmodium in the mosquito host: gene regulation on the move Article · 6 May 2019
- Prenatal Particulate Air Pollution and DNA Methylation in Newborns: An Epigenome-Wide Meta-Analysis Article · 1 May 2019
- Chromatin changes in Anopheles gambiae induced by Plasmodium falciparum infection Article · 7 Jan 2019
- Characterization of the accessible genome in the human malaria parasite Plasmodium falciparum Article · 17 Jul 2018
