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Insulin regulates neurovascular coupling through astrocytes

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Understanding human metabolic variability through computational and bioinformatic methods for precision nutrition

We develop and apply computational and bioinformatic tools to investigate how different nutrients, nutritional strategies,...

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Insulin-like growth factor I mitigates post-traumatic stress by inhibiting AMP-kinase in orexin neurons

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The neurobiology of insulin-like growth factor I: From neuroprotection to modulation of brain states

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The Role of Insulin-like Growth Factor I in Mechanisms of Resilience and Vulnerability to Sporadic Alzheimer's Disease

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A ROLE FOR ASTROCYTIC INSULIN-LIKE GROWTH FACTOR I RECEPTORS IN THE RESPONSE TO ISCHEMIC INSULT

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Transgenerational effects of exercise on mouse brain and cognition

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Grandfathers-to-Grandsons Transgenerational Transmission of Exercise Positive Effects on Cognitive Performance

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Nanoparticles targeting the central circadian clock: Potential applications for neurological disorders☆

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Interacciones hospedador-microbiota

Investigar las interacciones hospedador-microbiota en enfermedades complejas, con el objetivo de incluirlo en las intervenciones...

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High-throughput screening platform for precision nutrition in Non-Responsive Celiac Disease through 3D organ models and systems biology” (CD3DTech-CM TEC-2024/BIO-167)

The main objective of CD3DTech-CM is to develop the technological basis for creating a high-throughput...

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Inteligencia Artificial para la Prevención de Enfermedades Crónicas a través de una Nutrición Personalizada (AI4FOOD-CM Y2020/TCS-6654)

Obesity is a prevalent and preventable condition that has increased alarmingly in recent decades and...

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Gut Finder, an AI-based technology for Healthy Aging (CIVP21S13338)

El estudio del MICROBIOMA INTESTINAL ha emergido como un importante factor a tener en cuenta en...

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EPIADAPT

Epigenetics of adaptation in the human malaria parasite Plasmodium falciparum Despite being a major global...

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Intracellular trafficking of vesicles in hyperpolarized cells

Using a filamentous fungus as the model organism, we identify and characterize common eukaryotic and...

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Picture your microbes: A co-creation participatory action to empower citizens on nutritional health decisions (PoC47).

Non-communicable diseases (NCDs) are defined as diseases that are not transmissible directly from one person...

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NUTRIclock: a tool based on microbiome and artificial intelligence for implementing precision nutrition

The role of the gut microbiome in health and chronic conditions including gastrointestinal, neurological, cardiovascular...

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Food Nutrition Security Cloud (FNS-Cloud) (DT-SFS-26-2019).

Food Nutrition Security Cloud (FNS-Cloud) has launched the first ‘food cloud’, federating existing and emerging...

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CARBON CATABOLITE REPRESSION CAN ACCOUNT FOR THE TEMPORAL PATTERN OF EXPRESSION OF A PENICILLIN BIOSYNTHETIC GENE IN ASPERGILLUS-NIDULANS

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EXPRESSION OF FUNGAL GENES INVOLVED IN PENICILLIN BIOSYNTHESIS

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IN-VITRO BINDING OF THE 2-FINGER REPRESSOR CREA TO SEVERAL CONSENSUS AND NONCONSENSUS SITES AT THE IPNA UPSTREAM REGION IS CONTEXT-DEPENDENT

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Carbon regulation of penicillin biosynthesis in Aspergillus nidulans: A minor effect of mutations in creB and creC

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ACTIVATION OF THE ASPERGILLUS PACC TRANSCRIPTION FACTOR IN RESPONSE TO ALKALINE AMBIENT PH REQUIRES PROTEOLYSIS OF THE CARBOXY-TERMINAL MOIETY

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Three binding sites for the Aspergillus nidulans PacC zinc-finger transcription factor are necessary and sufficient for regulation by ambient pH of the isopenicillin N synthase gene promoter

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Specific DNA recognition by the Aspergillus nidulans three zinc finger transcription factor PacC

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The essential Aspergillus nidulans gene pmaA encodes an homologue of fungal plasma membrane H+-ATPases

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Putative membrane components of signal transduction pathways for ambient pH regulation in Aspergillus and meiosis in Saccharomyces are homologous

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The multiply-regulated gabA gene encoding the GABA permease of Aspergillus nidulans: a score of exons

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Ambient pH signal transduction in Aspergillus: completion of gene characterization (vol 33, pg 994, 1999)

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On the mechanism by which alkaline pH prevents expression of an acid-expressed gene

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On how a transcription factor can avoid its proteolytic activation in the absence of signal transduction

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Genome sequence of the brown rot fungal pathogen Monilinia laxa

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Ambient pH signaling regulates nuclear localization of the Aspergillus nidulans PacC transcription factor

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Proteomic Studies to Understand the Mechanisms of Peach Tissue Degradation by Monilinia laxa

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The pH signalling transcription factor PacC controls virulence in the plant pathogen Fusarium oxysporum

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Influence of light on the Monilinia laxa–stone fruit interaction

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Overlap of nuclear localisation signal and specific DNA-binding residues within the zinc finger domain of PacC

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A Secondary Metabolism Pathway Involved in the Production of a Putative Toxin Is Expressed at Early Stage of Monilinia laxa Infection

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Discrepancies between recombination frequencies and physical distances in Aspergillus nidulans: Implications for gene identification

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Rhizopus stolonifer Exhibits Necrotrophic Behavior when Causing Soft Rot in Ripe Fruit

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Nuclear export of the transcription factor NirA is a regulatory checkpoint for nitrate induction in Aspergillus nidulans

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Establishment of the ambient pH signaling complex in Aspergillus nidulans: PalI assists plasma membrane localization of PalH

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Aspergillus nidulans VeA subcellular localization is dependent on the importin alpha carrier and on light

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Two zinc finger transcription factors, CrzA and SltA, are involved in cation homoeostasis and detoxification in Aspergillus nidulans

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The tip growth apparatus of Aspergillus nidulans

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Preferential localization of the endocytic internalization machinery to hyphal tips underlies polarization of the actin cytoskeleton in Aspergillus nidulans

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NapA and NapB are the Aspergillus nidulans Nap/SET family members and NapB is a nuclear protein specifically interacting with importin alpha

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Functional and physical interaction of blue- and red-light sensors in Aspergillus nidulans

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Basic-zipper-type transcription factor FlbB controls asexual development in Aspergillus nidulans

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The bZIP-type transcription factor FlbB regulates distinct morphogenetic stages of colony formation in Aspergillus nidulans

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The 2008 update of the Aspergillus nidulans genome annotation: A community effort

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Morphology and development in Aspergillus nidulans: A complex puzzle

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Kapl, a non-essential member of the Pse1p/Imp5 karyopherin family, controls colonial and asexual development in Aspergillus nidulans

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Importin alpha is an essential nuclear import carrier adaptor required for proper sexual and asexual development and secondary metabolism in Aspergillus nidulans

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Aspergillus nidulans FlbE is an upstream developmental activator of conidiation functionally associated with the putative transcription factor FlbB

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The concerted action of bZip and cMyb transcription factors FlbB and FlbD induces brlA expression and asexual development in Aspergillus nidulans

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Nuclear Dynamics during Germination, Conidiation, and Hyphal Fusion of Fusarium oxysporum

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Identification of possible targets of the Aspergillus fumigatus CRZ1 homologue, CrzA

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FlbC is a putative nuclear C2H2 transcription factor regulating development in Aspergillus nidulans

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Cross-talk between light and glucose regulation controls toxin production and morphogenesis in Aspergillus nidulans

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Aspergillus nidulans asexual development: making the most of cellular modules

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Analysis of a novel calcium auxotrophy in Aspergillus nidulans

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Adaptative and Developmental Responses to Stress in Aspergillus nidulans

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Nuclear transporters in a multinucleated organism: functional and localization analyses in Aspergillus nidulans

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Elucidation of Functional Markers from Aspergillus nidulans Developmental Regulator FlbB and Their Phylogenetic Distribution

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8-Carbon oxylipins inhibit germination and growth, and stimulate aerial conidiation in Aspergillus nidulans

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GmcA Is a Putative Glucose-Methanol-Choline Oxidoreductase Required for the Induction of Asexual Development in Aspergillus nidulans

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Virulence Regulation of Phytopathogenic Fungi by pH

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Transcriptional Changes in the Transition from Vegetative Cells to Asexual Development in the Model Fungus Aspergillus nidulans

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The Aspergillus nidulans Peripheral ER: Disorganization by ER Stress and Persistence during Mitosis

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Role of the Zinc Finger Transcription Factor SltA in Morphogenesis and Sterigmatocystin Biosynthesis in the Fungus Aspergillus nidulans

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Phospho-regulation and nucleocytoplasmic trafficking of CrzA in response to calcium and alkaline-pH stress in Aspergillus nidulans

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Cytoplasmic Dynamics of the General Nuclear Import Machinery in Apically Growing Syncytial Cells

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The pH-Responsive PacC Transcription Factor of Aspergillus fumigatus Governs Epithelial Entry and Tissue Invasion during Pulmonary Aspergillosis

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In Aspergillus nidulans the Suppressors suaA and suaC Code for Release Factors eRF1 and eRF3 and suaD Codes for a Glutamine tRNA

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Tip-to-nucleus migration dynamics of the asexual development regulator FlbB in vegetative cells

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The beta-importin KAP8 (Pse1/Kap121) is required for nuclear import of the cellulase transcriptional regulator XYR1, asexual sporulation and stress resistance in Trichoderma reesei

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Refining the pH response in Aspergillus nidulans: A modulatory triad involving PacX, a novel zinc binuclear cluster protein

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Correction to: The pH-Responsive PacC Transcription Factor of Aspergillus fumigatus Governs Epithelial Entry and Tissue Invasion during Pulmonary Aspergillosis (PLoS Pathog, (2015) 11, [6])

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Conserved and Distinct Functions of the "Stunted" (StuA)-Homolog Ust1 During Cell Differentiation in the Corn Smut Fungus Ustilago maydis

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Beyond Asexual Development: Modifications in the Gene Expression Profile Caused by the Absence of the Aspergillus nidulans Transcription Factor FlbB

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A second component of the SltA-dependent cation tolerance pathway in Aspergillus nidulans

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The development of genetic and molecular markers to register and commercialize Penicillium rubens (formerly Penicillium oxalicum) strain 212 as a biocontrol agent

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The CRaZy calcium cycle

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Proteolytic activation of both components of the cation stress-responsive Slt pathway in Aspergillus nidulans

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New applications for known drugs: Human glycogen synthase kinase 3 inhibitors as modulators of Aspergillus fumigatus growth

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Neurons show the path: Tip-to-nucleus communication in filamentous fungal development and pathogenesisa

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Diverse regulation of the CreA carbon catabolite repressor in aspergillus nidulans

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Cation-stress-responsive transcription factors SltA and CrzA regulate morphogenetic processes and pathogenicity of colletotrichum gloeosporioides

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Carbon regulation of environmental pH by secreted small molecules that modulate pathogenicity in phytopathogenic fungi

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Apical control of conidiation in Aspergillus nidulans

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Ammonia activates pacC and patulin accumulation in an acidic environment during apple colonization by Penicillium expansum

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cpsA regulates mycotoxin production, morphogenesis and cell wall biosynthesis in the fungus Aspergillus nidulans

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Spatiotemporal dynamics of the calcineurin target CrzA

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Mutual independence of alkaline- and calcium-mediated signalling in Aspergillus fumigatus refutes the existence of a conserved druggable signalling nexus

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Boron Tolerance in Aspergillus nidulans Is Sustained by the SltA Pathway Through the SLC-Family Transporters SbtA and SbtB

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Transformation of Penicillium rubens 212 and expression of GFP and DsRED coding genes for visualization of plant-biocontrol agent interaction

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UrdA Controls Secondary Metabolite Production and the Balance between Asexual and Sexual Development in Aspergillus nidulans

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Modulation of calcineurin activity in Aspergillus nidulans: the roles of high magnesium concentrations and of transcriptional factor CrzA

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Rewiring of transcriptional networks as a major event leading to the diversity of asexual multicellularity in fungi