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Towards the global comprehension of the fungal cell; Knowledge for human welfare. PID2021-124278OB-I00

We often forget that fungi and animals are each others closest relatives. This is a...

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New insights on the structure and morphogenesis of Berne virus

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Molecular characterization of a new PToV strain. Evolutionary implications

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Longitudinal serological and virological study on porcine torovirus (PToV) in piglets from Spanish farms

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Detection of porcine torovirus by real time RT-PCR in piglets from a Spanish farm

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Seroprevalence of porcine torovirus (PToV) in Spanish farms

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Transcriptional Regulation of Olfactory Bulb Neurogenesis

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Transcriptional Heterogeneity of IgM(+) Cells in Rainbow Trout (Oncorhynchus mykiss) Tissues

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Lineage specific antigenic differences in porcine torovirus hemagglutinin-esterase (PToV-HE) protein

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A Global Transcriptome Analysis Reveals Molecular Hallmarks of Neural Stem Cell Death, Survival, and Differentiation in Response to Partial FGF-2 and EGF Deprivation

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Immunological Characterization of the Teleost Adipose Tissue and Its Modulation in Response to Viral Infection and Fat-Content in the Diet

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Early Immune Responses in Rainbow Trout Liver upon Viral Hemorrhagic Septicemia Virus (VHSV) Infection

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CCR7 Is Mainly Expressed in Teleost Gills, Where It Defines an IgD(+)IgM(-) B Lymphocyte Subset

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SYNTHESIS OF CYCLOBUTANE NUCLEOSIDES 2-PREPARATION OF THYMINE AND URACIL ANALOGUES

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Nurr1 blocks the mitogenic effect of FGF-2 and EGF, inducing olfactory bulb neural stem cells to adopt dopaminergic and dopaminergic-GABAergic neuronal phenotypes

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Molecular characterization of CD9 and CD63, two tetraspanin family members expressed in trout B lymphocytes

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Identification of Teleost Skin CD8 alpha(+) Dendritic-like Cells, Representing a Potential Common Ancestor for Mammalian Cross-Presenting Dendritic Cells

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Characterization of BAFF and APRIL subfamily receptors in rainbow trout (Oncorhynchus mykiss). Potential role of the BAFF/APRIL axis in the pathogenesis of proliferative kidney disease

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Cell-specific expression of insulin/insulin-like growth factor-I receptor hybrids in the mouse brain

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Insulin-like growth factor I modulates sleep through hypothalamic orexin neurons

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IGF-I Governs Cortical Inhibitory Synaptic Plasticity By Astrocyte Activation

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Circulating Insulin-Like Growth Factor I is Involved in the Effect of High Fat Diet on Peripheral Amyloid β Clearance

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INSULIN-LIKE GROWTH FACTOR I SENSITIZATION REJUVENATES SLEEP PATTERNS IN OLD MICE

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Promoting citizen science to bridge scientific research and society through participatory and educational initiatives

We are committed to training the next generation of interdisciplinary experts who integrate data science,...

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Astrocytic IGF-IRs Induce Adenosine-Mediated Inhibitory Downregulation and Improve Sensory Discrimination

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Insulin-like growth factor I couples metabolism with circadian activity through hypothalamic orexin neurons

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Tbr1 Misexpression Alters Neuronal Development in the Cerebral Cortex

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Morphological Diversity of Calretinin Interneurons Generated From Adult Mouse Olfactory Bulb Core Neural Stem Cells

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Investigating host–microbiota interactions in complex diseases through systems biology, network analysis, and advanced in vitro models

We employ systems biology approaches and complex network analysis to elucidate host–microbiota interactions in chronic...

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Insulin regulates neurovascular coupling through astrocytes

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Understanding human metabolic variability through computational and bioinformatic methods for precision nutrition

We develop and apply computational and bioinformatic tools to investigate how different nutrients, nutritional strategies,...

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Insulin-like growth factor I mitigates post-traumatic stress by inhibiting AMP-kinase in orexin neurons

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The neurobiology of insulin-like growth factor I: From neuroprotection to modulation of brain states

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The Role of Insulin-like Growth Factor I in Mechanisms of Resilience and Vulnerability to Sporadic Alzheimer's Disease

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A ROLE FOR ASTROCYTIC INSULIN-LIKE GROWTH FACTOR I RECEPTORS IN THE RESPONSE TO ISCHEMIC INSULT

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Transgenerational effects of exercise on mouse brain and cognition

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Grandfathers-to-Grandsons Transgenerational Transmission of Exercise Positive Effects on Cognitive Performance

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Nanoparticles targeting the central circadian clock: Potential applications for neurological disorders☆

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Interacciones hospedador-microbiota

Investigar las interacciones hospedador-microbiota en enfermedades complejas, con el objetivo de incluirlo en las intervenciones...

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High-throughput screening platform for precision nutrition in Non-Responsive Celiac Disease through 3D organ models and systems biology” (CD3DTech-CM TEC-2024/BIO-167)

The main objective of CD3DTech-CM is to develop the technological basis for creating a high-throughput...

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Inteligencia Artificial para la Prevención de Enfermedades Crónicas a través de una Nutrición Personalizada (AI4FOOD-CM Y2020/TCS-6654)

Obesity is a prevalent and preventable condition that has increased alarmingly in recent decades and...

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Gut Finder, an AI-based technology for Healthy Aging (CIVP21S13338)

El estudio del MICROBIOMA INTESTINAL ha emergido como un importante factor a tener en cuenta en...

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EPIADAPT

Epigenetics of adaptation in the human malaria parasite Plasmodium falciparum Despite being a major global...

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Intracellular trafficking of vesicles in hyperpolarized cells

Using a filamentous fungus as the model organism, we identify and characterize common eukaryotic and...

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Picture your microbes: A co-creation participatory action to empower citizens on nutritional health decisions (PoC47).

Non-communicable diseases (NCDs) are defined as diseases that are not transmissible directly from one person...

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NUTRIclock: a tool based on microbiome and artificial intelligence for implementing precision nutrition

The role of the gut microbiome in health and chronic conditions including gastrointestinal, neurological, cardiovascular...

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Food Nutrition Security Cloud (FNS-Cloud) (DT-SFS-26-2019).

Food Nutrition Security Cloud (FNS-Cloud) has launched the first ‘food cloud’, federating existing and emerging...

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CARBON CATABOLITE REPRESSION CAN ACCOUNT FOR THE TEMPORAL PATTERN OF EXPRESSION OF A PENICILLIN BIOSYNTHETIC GENE IN ASPERGILLUS-NIDULANS

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EXPRESSION OF FUNGAL GENES INVOLVED IN PENICILLIN BIOSYNTHESIS

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IN-VITRO BINDING OF THE 2-FINGER REPRESSOR CREA TO SEVERAL CONSENSUS AND NONCONSENSUS SITES AT THE IPNA UPSTREAM REGION IS CONTEXT-DEPENDENT

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Carbon regulation of penicillin biosynthesis in Aspergillus nidulans: A minor effect of mutations in creB and creC

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ACTIVATION OF THE ASPERGILLUS PACC TRANSCRIPTION FACTOR IN RESPONSE TO ALKALINE AMBIENT PH REQUIRES PROTEOLYSIS OF THE CARBOXY-TERMINAL MOIETY

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Three binding sites for the Aspergillus nidulans PacC zinc-finger transcription factor are necessary and sufficient for regulation by ambient pH of the isopenicillin N synthase gene promoter

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Specific DNA recognition by the Aspergillus nidulans three zinc finger transcription factor PacC

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The essential Aspergillus nidulans gene pmaA encodes an homologue of fungal plasma membrane H+-ATPases

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Putative membrane components of signal transduction pathways for ambient pH regulation in Aspergillus and meiosis in Saccharomyces are homologous

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The multiply-regulated gabA gene encoding the GABA permease of Aspergillus nidulans: a score of exons

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Ambient pH signal transduction in Aspergillus: completion of gene characterization (vol 33, pg 994, 1999)

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On the mechanism by which alkaline pH prevents expression of an acid-expressed gene

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On how a transcription factor can avoid its proteolytic activation in the absence of signal transduction

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Genome sequence of the brown rot fungal pathogen Monilinia laxa

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Ambient pH signaling regulates nuclear localization of the Aspergillus nidulans PacC transcription factor

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Proteomic Studies to Understand the Mechanisms of Peach Tissue Degradation by Monilinia laxa

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The pH signalling transcription factor PacC controls virulence in the plant pathogen Fusarium oxysporum

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Influence of light on the Monilinia laxa–stone fruit interaction

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Overlap of nuclear localisation signal and specific DNA-binding residues within the zinc finger domain of PacC

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A Secondary Metabolism Pathway Involved in the Production of a Putative Toxin Is Expressed at Early Stage of Monilinia laxa Infection

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Discrepancies between recombination frequencies and physical distances in Aspergillus nidulans: Implications for gene identification

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Rhizopus stolonifer Exhibits Necrotrophic Behavior when Causing Soft Rot in Ripe Fruit

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Nuclear export of the transcription factor NirA is a regulatory checkpoint for nitrate induction in Aspergillus nidulans

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Establishment of the ambient pH signaling complex in Aspergillus nidulans: PalI assists plasma membrane localization of PalH

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Aspergillus nidulans VeA subcellular localization is dependent on the importin alpha carrier and on light

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Two zinc finger transcription factors, CrzA and SltA, are involved in cation homoeostasis and detoxification in Aspergillus nidulans

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The tip growth apparatus of Aspergillus nidulans

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Preferential localization of the endocytic internalization machinery to hyphal tips underlies polarization of the actin cytoskeleton in Aspergillus nidulans

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NapA and NapB are the Aspergillus nidulans Nap/SET family members and NapB is a nuclear protein specifically interacting with importin alpha

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Functional and physical interaction of blue- and red-light sensors in Aspergillus nidulans

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Basic-zipper-type transcription factor FlbB controls asexual development in Aspergillus nidulans

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The bZIP-type transcription factor FlbB regulates distinct morphogenetic stages of colony formation in Aspergillus nidulans

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The 2008 update of the Aspergillus nidulans genome annotation: A community effort

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Morphology and development in Aspergillus nidulans: A complex puzzle

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Kapl, a non-essential member of the Pse1p/Imp5 karyopherin family, controls colonial and asexual development in Aspergillus nidulans

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Importin alpha is an essential nuclear import carrier adaptor required for proper sexual and asexual development and secondary metabolism in Aspergillus nidulans

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Aspergillus nidulans FlbE is an upstream developmental activator of conidiation functionally associated with the putative transcription factor FlbB

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The concerted action of bZip and cMyb transcription factors FlbB and FlbD induces brlA expression and asexual development in Aspergillus nidulans

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Nuclear Dynamics during Germination, Conidiation, and Hyphal Fusion of Fusarium oxysporum

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Identification of possible targets of the Aspergillus fumigatus CRZ1 homologue, CrzA

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FlbC is a putative nuclear C2H2 transcription factor regulating development in Aspergillus nidulans

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Cross-talk between light and glucose regulation controls toxin production and morphogenesis in Aspergillus nidulans

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Aspergillus nidulans asexual development: making the most of cellular modules

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Analysis of a novel calcium auxotrophy in Aspergillus nidulans

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Adaptative and Developmental Responses to Stress in Aspergillus nidulans

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Nuclear transporters in a multinucleated organism: functional and localization analyses in Aspergillus nidulans

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Elucidation of Functional Markers from Aspergillus nidulans Developmental Regulator FlbB and Their Phylogenetic Distribution

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8-Carbon oxylipins inhibit germination and growth, and stimulate aerial conidiation in Aspergillus nidulans

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GmcA Is a Putative Glucose-Methanol-Choline Oxidoreductase Required for the Induction of Asexual Development in Aspergillus nidulans

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Virulence Regulation of Phytopathogenic Fungi by pH

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Transcriptional Changes in the Transition from Vegetative Cells to Asexual Development in the Model Fungus Aspergillus nidulans

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The Aspergillus nidulans Peripheral ER: Disorganization by ER Stress and Persistence during Mitosis

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Role of the Zinc Finger Transcription Factor SltA in Morphogenesis and Sterigmatocystin Biosynthesis in the Fungus Aspergillus nidulans