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Cytokine profiling and transcriptomics in mononuclear cells define immune variants in Meniere Disease


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Trends in the diagnosis of paediatric sensorineural hearing loss: a scoping review of gene panels, exome and genome sequencing


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Different contribution of missense and loss-of-function variants to the genetic structure of familial and sporadic Meniere disease


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A Neuron-Like Cellular Model for Severe Tinnitus Associated with Rare Variations in the ANK2 Gene


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GRAST: a new way of genome reduction analysis using comparative genomics


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The evolution of the flagellar assembly pathway in endosymbiotic bacterial genomes


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Selection for translational robustness in Buchnera aphidicola, endosymbiotic bacteria of aphids


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Molecular Coevolution and the Three-Dimensionality of Natural Selection


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Computational biology methods and their application to the comparative genomics of endocellular symbiotic bacteria of insects


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Two chaperonin systems in bacterial genomes with distinct ecological roles


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Structural calibration of the rates of amino acid evolution in a search for Darwin in drifting biological systems


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Evolutionary microbial genomics: insights into bacterial host adaptation


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Preservation of genetic and regulatory robustness in ancient gene duplicates of Saccharomyces cerevisiae


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Essentiality Is a Strong Determinant of Protein Rates of Evolution during Mutation Accumulation Experiments in Escherichia coli


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The Phenotypic Plasticity of Duplicated Genes in Saccharomyces cerevisiae and the Origin of Adaptations


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RNAseq-based transcriptome comparison of Saccharomyces cerevisiae strains isolated from diverse fermentative environments


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Genome Mutational and Transcriptional Hotspots Are Traps for Duplicated Genes and Sources of Adaptations


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Expression properties exhibit correlated patterns with the fate of duplicated genes, their divergence, and transcriptional plasticity in Saccharomycotina.


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Chance and necessity in the genome evolution of endosymbiotic bacteria of insects


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Transcriptional Rewiring, Adaptation, and the Role of Gene Duplication in the Metabolism of Ethanol of Saccharomyces cerevisiae


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GWideCodeML: A Python Package for Testing Evolutionary Hypotheses at the Genome-Wide Level


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The Role of Ancestral Duplicated Genes in Adaptation to Growth on Lactate, a Non-Fermentable Carbon Source for the Yeast Saccharomyces cerevisiae


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Mapping the mutational landscape of a full viral proteome reveals distinct profiles of mutation tolerability


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Chronic infection ofCaenorhabditis elegansby Orsay virus induces age-dependent immunity and superinfection exclusion


research group

Systems Biotechnology Group


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Chronology of transcriptome and proteome expression during early Arabidopsis flower development


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Blind prediction of homo‐ and hetero‐protein complexes: The CASP13‐CAPRI experiment


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Modeling of Protein Complexes and Molecular Assemblies with pyDock


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Integrative modeling of protein‐protein interactions with pyDock for the new docking challenges


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New Insights into the Evolution of the Electron Transfer from Cytochrome f to Photosystem I in the Green and Red Branches of Photosynthetic Eukaryotes


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Prediction of protein assemblies, the next frontier: The CASP14‐CAPRI experiment


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pyDockDNA: A new web server for energy-based protein-DNA docking and scoring


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PDBe-KB: collaboratively defining the biological context of structural data


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Discriminating physiological from non‐physiological interfaces in structures of protein complexes: A community‐wide study


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Impact of AlphaFold on structure prediction of protein complexes: The CASP15‐CAPRI experiment


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Structural vulnerability in EPCR suggests functional modulation


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Bile acids target an exposed cavity in the glucocorticoid receptor modulating receptor self-assembly, chromatin binding and transcriptional activity


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Conservation of molecular responses upon viral infection in the non-vascular plant Marchantia polymorpha


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BENCHMARKING OF IMAGE ALIGNMENT METHODS FOR SPATIAL TRANSCRIPTOMICS DATA OF SPINAL CORD


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Molecular identification of yeasts associated with traditional egyptian dairy products


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Reconstruction of the Evolutionary History of Saccharomyces cerevisiae x S. kudriavzevii Hybrids Based on Multilocus Sequence Analysis


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Comparative genomics among Saccharomyces cerevisiae × Saccharomyces kudriavzevii natural hybrid strains isolated from wine and beer reveals different origins


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The molecular characterization of new types of Saccharomyces cerevisiae × S. kudriavzevii hybrid yeasts unveils a high genetic diversity


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Population structure and reticulate evolution of Saccharomyces eubayanus and its lager-brewing hybrids


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The genome sequence of saccharomyces eubayanus and the domestication of lager-brewing yeasts


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Mitochondrial introgression suggests extensive ancestral hybridization events amongSaccharomycesspecies


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Genome Sequence and Analysis of a Stress-Tolerant, Wild-Derived Strain of Saccharomyces cerevisiae used in Biofuels Research


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Enological characterization of Spanish Saccharomyces kudriavzevii strains, one of the closest relatives to parental strains of winemaking and brewing Saccharomyces cerevisiae × S. kudriavzevii hybrids


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Efficient engineering of marker-free synthetic allotetraploids of Saccharomyces


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Complex Ancestries of Lager-Brewing Hybrids Were Shaped by Standing Variation in the Wild Yeast Saccharomyces eubayanus


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In silico Whole Genome Sequencer And Analyzer (iWGS): A computational pipeline to guide the design and analysis of de novo genome sequencing studies


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ortho-metallation of P(m-MeC6H4)3 in dirhodium(II) tetraacetate. Molecular structure of Rh2(O2CCH3)2[(m-MeC6H3)P(m-MeC6H4)2]2(HO2CCH3)2·CH3CO2H


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Study of the interaction between [Cu(bipy)]2+ and oxalate in dimethyl sulfoxide. Crystal structure of [Cu2(bipy)2(H2O)2ox]SO4·[Cu(bipy)ox]


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Hybridization and adaptive evolution of diverse Saccharomyces species for cellulosic biofuel production


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Solution chemistry of N,N'-ethylenebis(salicylideneimine) and its copper(II), nickel(II) and iron(III) complexes


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Sppider: A species identification tool to investigate hybrid genomes with high-throughput sequencing


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Transition structures for hydride transfer reactions in vacuo and their role in enzyme catalysis


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Phylogeography of the wild Lager-brewing ancestor (Saccharomyces eubayanus) in Patagonia


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Transition structure and reactive complexes for hydride transfer in an isoalloxazine-nicotinamide complex. On the catalytic mechanism of glutathione reductase. An ab initio MO SCF study


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On the origins and industrial applications of Saccharomyces cerevisiae × Saccharomyces kudriavzevii hybrids


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Drugs and Nondrugs: An Effective Discrimination with Topological Methods and Artificial Neural Networks


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Evidence for loss and reacquisition of alcoholic fermentation in a fructophilic yeast lineage


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Discrimination and selection of new potential antibacterial compounds using simple topological descriptors


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Natural Variation in the Multidrug Efflux Pump SGE1 Underlies Ionic Liquid Tolerance in Yeast


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Debaryomyces hansenii Metabolism of Sulfur Amino Acids As Precursors of Volatile Sulfur Compounds of Interest in Meat Products


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Artificial neural networks and linear discriminant analysis: A valuable combination in the selection of new antibacterial compounds


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Mitochondrial DNA and temperature tolerance in lager yeasts


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A holistic classification system for check amounts based on neural networks with rejection


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Mitochondria-encoded genes contribute to evolution of heat and cold tolerance in yeast


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A comparative study using different topological representations in pattern recognition based drug activity characterization


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Using subspace-based learning methods for medical drug design and characterization


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Fermentation innovation through complex hybridization of wild and domesticated yeasts


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GridQTC: A desktop client for the computational chemistry grid infrastructure


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Into the wild: new yeast genomes from natural environments and new tools for their analysis


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An empirical evaluation of common vector based classification methods and some extensions


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Postglacial migration shaped the genomic diversity and global distribution of the wild ancestor of lager-brewing hybrids


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Learning improved feature rankings through decremental input pruning for support vector based drug activity prediction


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Synthetic hybrids of six yeast species


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Image recognition through incremental discriminative common vectors


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Efficient dimensionality reduction on undersampled problems through incremental discriminative common vectors


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Large-scale fungal strain sequencing unravels the molecular diversity in mating loci maintained by long-term balancing selection


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A linear cost algorithm to compute the discrete gabor transform


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Macroevolutionary diversity of traits and genomes in the model yeast genus Saccharomyces


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Null space based image recognition using incremental eigendecomposition


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Introgression between highly divergent fungal sister species


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Fast approximated discriminative common vectors using rank-one SVD updates


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The genetic architecture of low-temperature adaptation in the wine yeast Saccharomyces cerevisiae


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Drug activity characterization using one-class support vector machines with counterexamples


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Comparative Genomics Between Saccharomyces kudriavzevii and S. cerevisiae Applied to Identify Mechanisms Involved in Adaptation


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Adaptation of Saccharomyces Species to High-Iron Conditions


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Aneuploidy and Ethanol Tolerance in Saccharomyces cerevisiae


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Incremental Generalized Discriminative Common Vectors for Image Classification


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Genome structure reveals the diversity of mating mechanisms in Saccharomyces cerevisiae x Saccharomyces kudriavzevii hybrids, and the genomic instability that promotes phenotypic diversity


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IaaSMon: Monitoring Architecture for Public Cloud Computing Data Centers


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Genomic instability in an interspecific hybrid of the genus Saccharomyces: a matter of adaptability


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Postglacial history of a widespread wood-decaying fungus in Europe suggests migration out of multiple refugia followed by admixture


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Efficient Analysis and Synthesis Using a New Factorization of the Gabor Frame Matrix


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Metagenomic dynamics in Olea europaea after root damage and Verticillium dahliae infection


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Comparative genomics of infective Saccharomyces cerevisiae strains reveals their food origin


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Optimizing sweet potato production: insights into the interplay of plant sanitation, virus influence, and cooking techniques for enhanced crop quality and food security


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