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Computational procedures for optimal experimental design in biological systems

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Computational protein design methods for synthetic biology

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Computational proteomics on the grid

research group

Computational Synthetic Biology

research group

Computational Systems Biology (CNB)

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Computer aided design and optimization of sterilization of canned tuna

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Computer-aided design for metabolic engineering

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Computer-aided molecular design of pyrazolotriazines targeting glycogen synthase kinase 3

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Computing all sparse kinetic structures for a Lorenz system using optimization

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Computing optimal dynamic experiments for model calibration in predictive microbiology

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Computing optimal operating policies for the food industry

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Computing protein dynamics from protein structure with elastic network models

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Concatemerization increases the inhibitory activity of short, cell-penetrating, cationic and tryptophan-rich antifungal peptides

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Concentration-dependent mechanisms of cell penetration and killing by the de novo designed antifungal hexapeptide PAF26

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Conceptual and computational framework for logical modelling of biological networks deregulated in diseases

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Conditional analysis identifies three novel major histocompatibility complex loci associated with psoriasis

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Conditional language models enable the efficient design of proficient enzymes

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Conditional prediction of consecutive tumor evolution using cancer progression models: What genotype comes next?

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CONDITIONS RESTRICTING DEPOLARIZATION-DEPENDENT CALCIUM INFLUX IN SYNAPTOSOMES REVEAL A GRADED RESPONSE OF P96-DEPHOSPHORYLATION AND A TRANSIENT DEPHOSPHORYLATION OF P65

project

Conexión CSIC en Biología Computacional y Bioinformática (BCBHub)

This is a CSIC-funded project to build a community of experts and resources in Computational...

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Confinement exposure induces glucose regulated protein 75 (GRP75/mortalin/mtHsp70/PBP74/HSPA9B) in the hepatic tissue of gilthead sea bream (Sparus aurata L.)

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Conformal prediction for uncertainty quantification in dynamic biological systems

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Conformation and ortho steric effects in a series of 2-(pyrazol-1-yl)quinolines

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Conformational flexibility of bacterial RNA polymerase

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Conformational heterogeneity of unbound proteins enhances recognition in protein-protein encounters

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Conformational transitions in human translin enable nucleic acid binding

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Connectivity of Neutral Networks, Overdispersion, and Structural Conservation in Protein Evolution

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Consequences of a low protein diet on the liver and longissimus dorsi transcriptome of Duroc x Iberian crossbred pigs

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Conservation of molecular responses upon viral infection in the non-vascular plant Marchantia polymorpha

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Conserved and Distinct Functions of the “Stunted” (StuA)-Homolog Ust1 During Cell Differentiation in the Corn Smut Fungus Ustilago maydis

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Conserved nucleotides surrounding the trans-splicing acceptor site and the translation initiation codon in Leishmania genes.

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Considerations to Improve Functional Annotations in Biological Databases

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Construction of a chassis for hydrogen production: physiological and molecular characterization of a Synechocystis sp PCC 6803 mutant lacking a functional bidirectional hydrogenase

tool

consumeresources

Code to perform large-scale population dynamics simulations of species and resources.

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Contamination or serendipity – doing the wrong thing by chance

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Context-Aware Biosensor Design Through Biology-Guided Machine Learning and Dynamical Modeling

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Continuous flexibility analysis of SARS-CoV-2 Spike prefusion structures

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Contractile injection systems of bacteriophages and related systems

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Contribution of galloylation and polymerization to the antioxidant activity of polyphenols in fish lipid systems

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Control of electrical turbulence by periodic excitation of cardiac tissue

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Control of the respiratory metabolism of Thermus thermophilus by the nitrate respiration conjugative element NCE

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Convergence and horizontal gene transfer drive the evolution of anaerobic methanotrophy in archaea

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Coordinated activation of the metabolic pathways induced by LED blue light in citrus fruit

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Copy number variation in the genomes of domestic animals

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Copy Number Variation on ABCC2-DNMBP Loci Affects the Diversity and Composition of the Fecal Microbiota in Pigs

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Copy number variation on ABCC2-DNMBP loci impacts the diversity and composition of the gut microbiota in pigs

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Correction of GSK3β in DM1 reduces the mutant RNA and improves postnatal survival of DMSXL mice

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Correction to: The pH-Responsive PacC Transcription Factor of Aspergillus fumigatus Governs Epithelial Entry and Tissue Invasion during Pulmonary Aspergillosis (PLoS Pathog, (2015) 11, [6])

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Correction: A slow axon antidromic blockade hypothesis for tremor reduction via deep brain stimulation (PLoS ONE (2013) 8, 9 (e73456) DOI: 10.1371/journal.pone.0073456)

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Correction: An Epistatic Interaction between the PAX8 and STK17B Genes in Papillary Thyroid Cancer Susceptibility

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Correction: Crystal structure of the fibre head domain of the atadenovirus snake adenovirus 1

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Correction: Gómez et al. Long-Term Effect of Maternal Antioxidant Supplementation on the Lipid Profile of the Progeny According to the Sow’s Parity Number. Antioxidants 2024, 13, 379

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Corrigendum: Bioinformatics in Latin America and SoIBio impact, a tale of spin-off and expansion around genomes and protein structures [Briefings in Bioinformatics, (2017)] doi: 10.1093/bib/bbx064

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Corrigendum: miARma-Seq: a comprehensive tool for miRNA, mRNA and circRNA analysis

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Corrigendum: Stochastic Individual-Based Modeling of Bacterial Growth and Division Using Flow Cytometry [Front. Microbiol., 8, (2018)(2626)] DOI: 10.3389/fmicb.2017.02626

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Corrigendum: The human mitochondrial transcription factor A is a versatile G-quadruplex binding protein (Scientific Reports (2017) 7 (43992) DOI: 10.1038/srep43992)

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Corrigendum: The tryptophan/histidine interaction in α-helices (J. Mol. Biol. (1997) 267 (184-197))

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Corrigendum: Transmissibility, hospitalization, and intensive care admissions due to omicron compared to delta variants of SARS-CoV-2 in Catalonia: A cohort study and ecological analysis(Front. Public Health, (2022), 10, (961030), 10.3389/fpubh.2022.961030)

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Cortactin (CTTN) overexpression in osteosarcoma correlates with advanced stage and reduced survival

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Cortistatin deficiency reveals a dysfunctional brain endothelium with impaired gene pathways, exacerbated immune activation, and disrupted barrier integrity

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Cortistatin regulates fibrosis and myofibroblast activation in experimental hepatotoxic‐ and cholestatic‐induced liver injury

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Country-report pattern corrections of new cases allow accurate 2-week predictions of COVID-19 evolution with the Gompertz model

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Covariation of Life-History Traits in Lacertid Lizards: A Comparative Study

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Cover Feature: Self‐Immolation of a Bacterial Dehydratase Enzyme by its Epoxide Product (Chem. Eur. J. 36/2020)

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Cover Image

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COVID-19 progression and convalescence in common variable immunodeficiency patients show dysregulated adaptive immune responses and persistent type I interferon and inflammasome activation

tool

COVID-19 Structural Hub

Since the COVID-19 outbreak many molecular structure models, have been generated to identify new therapeutic...

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COVID-19: Drug Targets and Potential Treatments

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CPD

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CPD Researchers

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Cpn60 is exclusively localized into mitochondria of rat liver and embryonic Drosophila cells

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cpsA regulates mycotoxin production, morphogenesis and cell wall biosynthesis in the fungus Aspergillus nidulans

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CPUs Number

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Crash of a population of the marine heterotrophic flagellate Cafeteria roenbergensis by viral infection

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Creating Reference Datasets for Systems Biology Applications Using Text Mining

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Creation of hybrid nanorods from sequences of natural trimeric fibrous proteins using the fibritin trimerization motif

researcher

Cristóbal Coronel Guisado

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Critical Assessment of Parameter Estimation Methods in Models of Biological Oscillators

project

Critical role for alternative splicing in conferring risk for T1D

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CRNreals: A toolbox for distinguishability and identifiability analysis of biochemical reaction networks

research line

Crop Genomics and Breeding Methods

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Cross-Over between Discrete and Continuous Protein Structure Space: Insights into Automatic Classification and Networks of Protein Structures

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Cross-talk between light and glucose regulation controls toxin production and morphogenesis in Aspergillus nidulans

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Crosstalk between Phosphodiesterase 7 and Glycogen Synthase Kinase-3: Two Relevant Therapeutic Targets for Neurological Disorders

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Cryo-EM structure of enteric adenovirus HAdV-F41 highlights structural divergence among human adenoviruses

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Cryptic vector divergence masks vector‐specific patterns of infection: an example from the marine cycle of Lyme borreliosis

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Crystal structure of a heat and protease-stable part of the bacteriophage T4 short tail fibre

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Crystal structure of the avian reovirus inner capsid protein σA

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Crystal Structure of the Carboxy-Terminal Region of the Bacteriophage T4 Proximal Long Tail Fiber Protein Gp34

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Crystal structure of the endopolygalacturonase from the phytopathogenic fungus Colletotrichum lupini and its interaction with polygalacturonase- inhibiting proteins

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Crystal structure of the fibre head domain of the atadenovirus snake adenovirus 1

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Crystal structure of thioflavin-T and its binding to amyloid fibrils: Insights at the molecular level

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Crystallization and preliminary X-ray characterization of the catalytic domain of collagenase G from Clostridium histolyticum

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Crystallization of F1-ATPase from bovine heart mitochondria.

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Crystallization of the avian reovirus double-stranded RNA-binding and core protein sigmaA.