MirCure

MirCure is a software for quality control, filtering, and curation of microRNA candidates. It evaluates miRNA-specific features based on gene expression, biogenesis, and conservation data to generate scores used to assess the reliability of miRNA annotations. The tool includes a graphical interface for manual curators to browse supporting evidence.

Info

Members (researchers): Ana Conesa

Research Groups: Genomics of Gene Expression

Contact Email: ana.conesa@csic.es

Tool Repository: https://github.com/ConesaLab/MirCure

Documentation: https://github.com/ConesaLab/MirCure

Institution: Instituto de Biología Integrativa de Sistemas (I2SYSBIO)

Application domain:

Annotation tools, Bioinformatics Software and Tools, Data Analysis, Desktop application, RNA Sequencing (RNA-seq), Transcriptomics

Technical details
Type of application
  • Desktop application
Software compatibility
  • Linux
  • Mac
  • Windows
Hardware requirements
  • No specific hardware requirements
Programming language
  • R
Type of containerization
  • Docker
Wrapper type
  • None
Input file formats
  • bam
  • fasta
  • gff
Output file formats
  • fasta
  • gff
  • pdf
Compatibility with other tools
  • mirDeep2: MirCure is compatible with mirDeep2 output for further validation and curation of miRNA candidates which shows its interoperability with existing miRNA discovery tools