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Design of a low-density SNP panel for intramuscular fat content and fatty acid composition of backfat in free-range Iberian pigs

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Design of clone-specific probes from genome sequences for rapid PCR-typing of outbreak pathogens

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Design Principles of Biological Oscillators through Optimization: Forward and Reverse Analysis

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Design, synthesis and structural analysis of mixed α/β-peptides that adopt stable cyclic hairpin-like conformations

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Design, synthesis, and biological evaluation of dual binding site acetylcholinesterase inhibitors: New disease-modifying agents for Alzheimer’s disease

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Design, synthesis, and structural analysis of turn modified cyclo-(αβ³αβ²α)2 peptide derivatives toward crystalline hexagon-shaped cationic nanochannel assemblies

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DESIGNING A TRANSCRIPTOME NEXT-GENERATION SEQUENCING PROJECT FOR A NONMODEL PLANT SPECIES

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Designing and executing scientific workflows with a programmable integrator

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Detailed kinetic model describing new oligosaccharides synthesis using different β-galactosidases

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Detecting selection for negative design in proteins through an improved model of the misfolded state

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Detecting Selection on Protein Stability through Statistical Mechanical Models of Folding and Evolution

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Detection of Domestication Signals through the Analysis of the Full Distribution of Fitness Effects

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Detection of novel fusion-transcripts by RNA-Seq in T-cell lymphoblastic lymphoma

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Detection of porcine torovirus by real time RT-PCR in piglets from a Spanish farm

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Detection of QTL affecting fatty acid composition in the pig

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Detection of recurrent copy number alterations in the genome: taking among-subject heterogeneity seriously

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Detection of Transient Bacteraemia following Dental Extractions by 16S rDNA Pyrosequencing: A Pilot Study

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Detection of vancomycin-resistant Enterococcus faecium hospital-adapted lineages in municipal wastewater treatment plants indicates widespread distribution and release into the environment

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Determination of carotenoid pigments in several tree leaves by reversed-phase high-performance liquid chromatography

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Determination of Key Residues for Catalysis and RNA Cleavage Specificity ONE MUTATION TURNS RNase II INTO A “SUPER-ENZYME”

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Determination of polychlorinated biphenyls in milk samples by saponification – Solid-phase microextraction

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Determination of Self- and Inter-(in)compatibility Relationships in Apricot Combining Hand-Pollination, Microscopy and Genetic Analyses

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Determination of the melon chloroplast and mitochondrial genome sequences reveals that the largest reported mitochondrial genome in plants contains a significant amount of DNA having a nuclear origin

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Determination of thermal conductivity, specific heat and thermal diffusivity of albacore (Thunnus alalunga)

tool

Detspace

Tackling climate change challenges requires replacing current chemical industrial processes through the rational and sustainable...

orcid publication

DetSpace: a web server for engineering detectable pathways for bio-based chemical production

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Developing a DNA biofoundry towards the AI-guided exploration of microbial chemical space.

We are actively involved in the development of a DNA biofoundry (CNBio) that integrates advanced...

project

Developing a European American NGS Network (DEANN)

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Developing an enzyme selection tool supporting multiple hosts contexts

project

Developing an organoid Dynamic Screening Platform to Evaluate Immuno-Oncology Drug activities in a Clinically Relevant Preclinical Model

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Developing novel classes of protein kinase CK1δ inhibitors by fusing [1,2,4]triazole with different bicyclic heteroaromatic systems

project

Developing the Functional Iso-Transcriptomics framework

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Development and Evaluation of an AxiomTM 60K SNP Array for Almond (Prunus dulcis)

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Development and Genome-Wide Analysis of a Blast-Resistant japonica Rice Variety

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Development of a 64 SNV panel for breed authentication in Iberian pigs and their derived meat products

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Development of a citrus genome-wide EST collection and cDNA microarray as resources for genomic studies

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Development of a Computational Model of Abscess Formation

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Development of a FungalBraid Penicillium expansum‐based expression system for the production of antifungal proteins in fungal biofactories

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Development of a library of components in ecosimpro for the operation of thermal processing plants,Desarrollo de una librería de componentes en ecosimpro para la operación de plantas de procesamiento térmico de alimentos

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Development of A New Delivery System Based on Drug-Loadable Electrospun Nanofibers for Psoriasis Treatment

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Development of a PBPK Model for Silver Accumulation in Chub Infected with Acanthocephalan Parasites

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Development of a toxicokinetic-toxicodynamic model simulating chronic copper toxicity to the Zebra mussel based on subcellular fractionation

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Development of Blood-Brain Barrier Permeable Nitrocatechol-Based Catechol O-Methyltransferase Inhibitors with Reduced Potential for Hepatotoxicity

project

Development of Computational Approaches for the characterization and functional annotation of long-non-coding RNA (Annot-lncRNA)

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Development of Computational Tools for Spatial Transcriptomics Data Analysis

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Development of efficient methods for calculating paths of minimum or maximum parameter values (e.g., minimum energy paths) through surfaces of any number of dimensions.

MEPSAnd: Minimum Energy Path Surface Analysis over n-dimensional surfaces [http://bioweb.cbm.uam.es/software/MEPSAnd/] MEPSA: Minimum Energy Pathway A...

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Development of Genomic tools for Population Analysis of Variability

Statistical Studies to develop methods to better understand the genetic variability. Development of Software and...

project

Development of HPC and AI-Based Tools for Large-Scale Spatial Transcriptomics and Single-Cell Data Integration

In today’s science, data processing technologies play an increasingly crucial role, driven by technological advances...

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Development of methods for long-reads transcriptomics

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project

Development of methods for transcript quantification and differential expression analysis using long-read sequencing technologies

project

Development of multiomics methods for the integrative study of the Yeast Metabolic Cycle

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Development of new methodology for the energetic description of protein interactions

We are exploring the use of pyDock energy-based function to describe the energetics of protein-protein...

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Development of novel polypharmacology-based cancer immunotherapy strategies targeting the purinergic signalling pathway

Blocking the A2B Adenosine Receptor is a selective mechanism of therapeutic intervention, since this receptor...

orcid publication

Development of Quantitative Proteomics Using iTRAQ Based on the Immunological Response of Galleria mellonella Larvae Challenged with Fusarium oxysporum Microconidia

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Development of the GENIPOL European flounder (Platichthys flesus) microarray and determination of temporal transcriptional responses to cadmium at low dose

project

Development of tools of new generation for gene expression data analysis and implementation in the improved GEPAS platform

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Development, Characterization and Experimental Validation of a Cultivated Sunflower (Helianthus annuus L.) Gene Expression Oligonucleotide Microarray

research group

Development, Wiring and Function of Cerebellar Circuits

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Developmental conditions modulate DNA methylation at the glucocorticoid receptor gene with cascading effects on expression and corticosterone levels in zebra finches

research group

Developmental Neurobiology Unit

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Developmental ORIgins of Healthy and Unhealthy AgeiNg: The Role of Maternal Obesity – Introduction to DORIAN

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Developmental Pattern Formation: Spanish Contributions from a Biophysical Perspective

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Developmental regulators FlbE/D orchestrate the polarity site-to-nucleus dynamics of the fungal bZIP transcription factor FlbB

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DFprot: A webtool for predicting local chain deformability

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DGCR8-mediated disruption of miRNA biogenesis induces cellular senescence in primary fibroblasts

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Diet-host-microbe interactions in health and disease

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Dietary fat, the gut microbiota, and metabolic health – a systematic review conducted within the MyNewGut project

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Dietary oils mediate cortisol kinetics and the hepatic mRNA expression profile of stress-responsive genes in gilthead sea bream (Sparus aurata) exposed to crowding stress. Implications on energy homeostasis and stress susceptibility

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Dietary Supplementation with Sugar Beet Fructooligosaccharides and Garlic Residues Promotes Growth of Beneficial Bacteria and Increases Weight Gain in Neonatal Lambs

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Dietary β-glucan stimulate complement and C-reactive protein acute phase responses in common carp (Cyprinus carpio) during an Aeromonas salmonicida infection

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Differences in Behavior During Early Nectarine Infection Among Main Monilinia spp. Causing Brown Rot

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Differences in firing efficiency, chromatin and transcription underlie the developmental plasticity of the Arabidopsis originome

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Differences in firing efficiency, chromatin, and transcription underlie the developmental plasticity of the Arabidopsis DNA replication origins

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Differences in gene expression profiling and biomarkers between histological colorectal carcinoma subsets from the serrated pathway

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Differences in the Loin Tenderness of Iberian Pigs Explained through Dissimilarities in Their Transcriptome Expression Profile

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Different contribution of missense and loss-of-function variants to the genetic structure of familial and sporadic Meniere disease

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Different ecological processes drive the assembly of dominant and rare root-associated bacteria in a promiscuous legume

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Different Effect of Vitamin E or Hydroxytyrosol Supplementation to Sow’s Diet on Oxidative Status and Performances of Weaned Piglets

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Different HCV Exposure Drives Specific miRNA Profile in PBMCs of HIV Patients

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Different Lactobacillus populations dominate in “Chorizo de León” manufacturing performed in different production plants

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Different strategies for controlling pressure during the cooling stage in batch retorts

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Differential contribution of the two major polygalacturonases from Penicillium digitatum to virulence towards citrus fruit

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Differential expression and co-expression reveal cell types relevant to genetic disorder phenotypes

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Differential expression in RNA-seq: A matter of depth

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Differential expression of sarcoplasmic proteins in four heterogeneous ovine skeletal muscles

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Differential Gene Expression in Ovaries of Pregnant Pigs with High and Low Prolificacy Levels and Identification of Candidate Genes for Litter Size

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Differential metabolic and gene expression profile of juvenile common dentex (Dentex dentex L.) and gilthead sea bream (Sparus aurata L.) in relation to redox homeostasis

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Differential Modulation of Quorum Sensing Signaling through QslA in Pseudomonas aeruginosa Strains PAO1 and PA14

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Differential proinflammatory signature in vestibular migraine and meniere disease

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Differential susceptibility to noise of mixed Turing and Hopf modes in a photosensitive chemical medium

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Differential tissue expression of uncoupling proteins in gilthead sea bream (Sparus aurata L): Lessons from UCP1 and UCP3 in fish

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Differential Tomato Transcriptomic Responses Induced by Pepino Mosaic Virus Isolates with Differential Aggressiveness

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Differentiation of live and heat-killed E. coli by microwave impedance spectroscopy

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Differently Regulated Gene-Specific Activity of Enhancers Located at the Boundary of Subtopologically Associated Domains: TCRα Enhancer

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Diffusivity Estimation for Activator–Inhibitor Models: Theory and Application to Intracellular Dynamics of the Actin Cytoskeleton

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Digital evolution

Studying evolution in the lab provides valuable insights but is often constrained by long timescales...

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Dimeric structure of the coxsackievirus and adenovirus receptor D1 domain at 1.7 A resolution.

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Dioxides of bicyclic thiadiazines: a new family of smooth muscle relaxants

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Direct and maternal additive effects are not the main determinants of Iberian piglet perinatal mortality

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Direct functional assessment of the composite phenotype through multivariate projection strategies