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Multiobjective optimization of gene circuits for metabolic engineering

project

Multiómica espacial y unicelular: un enfoque integrador para el estudio del impacto de los disruptores endocrinos en las células germinales de peces durante la pubertad (GERMTOX)

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Multiomics Data Integration in Time Series Experiments

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Multiscale dynamics of macromolecular biomachines

We address the study and simulation of the dynamics of large biomolecular systems Normal-Mode Analysis...

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Multiscale model of the different modes of cancer cell invasion

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Multispectral confocal 3D imaging of intact healthy and tumor tissue using mLSR-3D

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Multitarget Drug Discovery for Alzheimer’s Disease: Triazinones as BACE-1 and GSK-3 beta Inhibitors

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Multitarget Hybrid Fasudil Derivatives as a New Approach to the Potential Treatment of Amyotrophic Lateral Sclerosis

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Multivariate Curve Resolution (MCR). Solving the mixture analysis problem

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Multivariate curve resolution applied to the analysis and resolution of two-dimensional [¹H,¹⁵N] NMR reaction spectra

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Multivariate resolution of NMR labile signals by means of hard- and soft-modelling methods

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Muscle Transcriptome Analysis Reveals Molecular Pathways Related to Oxidative Phosphorylation, Antioxidant Defense, Fatness and Growth in Mangalitsa and Moravka Pigs

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Mutagenesis of human neuropeptide Y/peptide YY receptor Y2 reveals additional differences to Y1 in interactions with highly conserved ligand positions

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Mutagenesis of specific amino acids converts carnitine acetyltransferase into carnitine palmitoyltransferase

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Mutant PRPF8 Causes Widespread Splicing Changes in Spliceosome Components in Retinitis Pigmentosa Patient iPSC-Derived RPE Cells

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Mutation Bias Favors Protein Folding Stability in the Evolution of Small Populations

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Mutational mechanisms shaping the coding and noncoding genome of germinal center derived B-cell lymphomas

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Mutational Spectrum of Maple Syrup Urine Disease in Spain

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Mutations and Variants in the Cohesion Factor Genes NIPBL, SMC1A, and SMC3 in a Cohort of 30 Unrelated Patients With Cornelia de Lange Syndrome

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Mutations That Hamper Dimerization of Foot-and-Mouth Disease Virus 3A Protein Are Detrimental for Infectivity

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Mutual independence of alkaline- and calcium-mediated signalling in Aspergillus fumigatus refutes the existence of a conserved druggable signalling nexus

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Mutualism supports biodiversity when the direct competition is weak

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Mutualistic interactions reshuffle the effects of climate change on plants across the tree of life

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MYB transcription factors drive evolutionary innovations in Arabidopsis fruit trichome patterning

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Mycobacterium tuberculosis Complex Exhibits Lineage-Specific Variations Affecting Protein Ductility and Epitope Recognition

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Mycobacterium tuberculosis complex exhibits lineage-specific variations affecting protein ductility and epitope recognition

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Mycobacterium tuberculosis lineage 1 genetic diversity in Pará, Brazil, suggests common ancestry with east-African isolates potentially linked to historical slave trade

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Mycobacterium tuberculosis shikimate kinase inhibitors: design and simulation studies of the catalytic turnover.

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Mycobacterium tuberculosis whole genome sequencing and protein structure modelling provides insights into anti-tuberculosis drug resistance

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Mycoheterotrophic plants preferentially target arbuscular mycorrhizal fungi that are highly connected to autotrophic plants

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Myriads of protein families, and still counting.

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Mytilus galloprovincialis Myticin C: A Chemotactic Molecule with Antiviral Activity and Immunoregulatory Properties

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N-benzylpiperidine derivatives of 1,2,4-thiadiazolidinone as new acetylcholinesterase inhibitors

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N-GLUCOSYL-5-AMINO-4-CARBAMOYLIMIDAZOLES AND 4-ETHOXYCARBONYLIMIDAZOLES AS POTENTIAL PRECURSORS OF 4-OXOIMIDAZO[4,5-C]-1,2,6-THIADIAZINE 2,2-DIOXIDES

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N’-Phenylacetohydrazide Derivatives as Potent Ebola Virus Entry Inhibitors with an Improved Pharmacokinetic Profile

acf-field

Name of the institution

name_of_the_institution

acf-field

Name of the institution

name_of_the_institution

acf-field

Name of the institution to CPD

name_of_the_institution_to_cpd

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Named entity recognition and normalization: A domain-specific language approach

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Nanomechanics of the Cadherin Ectodomain “CANALIZATION” BYCa2 BINDING RESULTS IN A NEW MECHANICAL ELEMENT

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Nanoparticles targeting the central circadian clock: Potential applications for neurological disorders☆

project

NANOSEAOMICS: Combinación de técnicas -ómicas y biosensores nanotecnológicos para la detección de riesgos biológicos en alimentos de origen marino.

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NapA and NapB are the Aspergillus nidulans Nap/SET family members and NapB is a nuclear protein specifically interacting with importin alpha

researcher

Narciso Martín Quijada

acf-field

National research networks

national_research_networks

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National research networks

national_research_networks

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Natural bioactive antioxidants for the enrichment of seafood

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Natural Fibrous Proteins: Structural Analysis, Assembly, and Applications

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Natural triple beta-stranded fibrous folds.

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Natural variation in stress response gene activity in the allopolyploid Arabidopsis suecica

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Natural Variation in the Multidrug Efflux Pump SGE1 Underlies Ionic Liquid Tolerance in Yeast

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NBI-RPRGM for multi-objective optimization design of bio-processes

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Near Atomic Structure of an Atadenovirus Reveals a Conserved Capsid-Binding Motif and Intergenera Variations in Cementing Proteins

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Near-atomic cryo-EM structure of PRC1 bound to the microtubule

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Near-atomic structure of an atadenovirus reveals a conserved capsid-binding motif and intergenera variations in cementing proteins

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Neddylation inhibits CtIP-mediated resection and regulates DNA double strand break repair pathway choice

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Negative filament tension at high excitability in a model of cardiac tissue

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Negative filament tension in the Luo-Rudy model of cardiac tissue

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Negative resistance and anomalous hysteresis in a collective molecular motor

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Negative Tension of Scroll Wave Filaments and Turbulence in Three-Dimensional Excitable Media and Application in Cardiac Dynamics

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Negative-tension instability of scroll waves and Winfree turbulence in the Oregonator model

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Negligible cytotoxicity induced by different titanium dioxide nanoparticles in fish cell lines

tool

NeoAntigens Prediction@CNB (NAP-CNB)

NeoAntigens Prediction@CNB (NAP-CNB) is a tool for the prediction of neoantigenic peptides from RNA-seq or...

researcher

Nerea Sanchis

researcher

Neris García González

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Nestedness versus modularity in ecological networks: two sides of the same coin?

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Network pharmacology reveals multitarget mechanism of action of drugs to be repurposed for COVID-19

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Network theory in control engineering: Applications in dynamic analysis and process control,La teoría de redes en ingeniería de control: Aplicación al análisis dinámico y al control de procesos

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Network-Based Methods for Approaching Human Pathologies from a Phenotypic Point of View

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Networks of spatial genetic variation across species

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Neural networks for variational problems in engineering

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Neurodevelopmental Disorders Associated with PSD-95 and Its Interaction Partners

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Neurofuzzy model based predictive control for thermal batch processes

research line

Neuroinflammation

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Neurons show the path: Tip-to-nucleus communication in filamentous fungal development and pathogenesisa

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Neuroprotective effect of the new thiadiazolidinone NP00111 against oxygen-glucose deprivation in rat hippocampal slices: Implication of ERK1/2 and PPAR gamma receptors

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Neuroprotective efficacy of quinazoline type phosphodiesterase 7 inhibitors in cellular cultures and experimental stroke model

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Neutral and adaptive genomic variation in hybrid zones of two ecologically diverged Petunia species (Solanaceae)

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Neutral Evolution of Model Proteins: Diffusion in Sequence Space and Overdispersion

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Neutrality Tests for Sequences with Missing Data

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Neutralization of Human Respiratory Syncytial Virus Infectivity by Antibodies and Low-Molecular-Weight Compounds Targeted against the Fusion Glycoprotein

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Neutralization of viral infectivity by zebrafish c-reactive protein isoforms.

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Neutralization susceptibility of African swine fever virus is dependent on the phospholipid composition of viral particles

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Neutralizing antibodies to different proteins of African swine fever virus inhibit both virus attachment and internalization

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Neutrophils Promote Glioblastoma Tumor Cell Migration after Biopsy

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New 1,2,6-thiadiazine dioxide acyclonucleosides: synthesis and antiviral evaluation

research line

New AI-based methods for the structural modeling of protein assemblies: integration of pyDock and AlphaFold

We are using AI-based methods like AlphaFold to improve structural modeling of protein-protein complexes. Our...

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New applications for known drugs: Human glycogen synthase kinase 3 inhibitors as modulators of Aspergillus fumigatus growth

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New approach for phylogenetic tree recovery based on genome-scale metabolic networks

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New case of mitochondrial HMG-CoA synthase deficiency. Functional analysis of eight mutations

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New challenges in gene expression data analysis and the extended GEPAS

project

New Drought- and Heat-Tolerant Blueberry Varieties through Advanced Genomic Selection

project

New drugs to inhibit Carbapenemases. Discovery of compounds by structural design (DrugCarbapenem)

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New efficient substrates for semicarbazide-sensitive amine oxidase/VAP-1 enzyme: Analysis by SARs and computational docking

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New electron microscopy database and deposition system

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New generation of elastic network models

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New Genes Involved in Osmotic Stress Tolerance in Saccharomyces cerevisiae

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New insight into the SSC8 genetic determination of fatty acid composition in pigs

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New insights into the diversity of marine picoeukaryotes

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New Insights into the Evolution of the Electron Transfer from Cytochrome f to Photosystem I in the Green and Red Branches of Photosynthetic Eukaryotes