Detalle de: Alignment-Free Tool for Assemblies and Reads in Genomic Surveillance of Tuberculosis
| Title | Alignment-Free Tool for Assemblies and Reads in Genomic Surveillance of Tuberculosis |
| Abstract |
Whole-genome sequencing strengthens tuberculosis surveillance, but incomplete lineage schemes can misclassify isolates. We developed Pathotypr, an alignment-free tool for assemblies and reads, using 2,145 markers derived from 26,813 genomes. Across 88,071 samples, Pathotypr improved concordance, expanded uncommon lineage coverage, and detected resistance markers, supporting molecular epidemiology and public health surveillance. |
| Apa Reference | Ruiz-Rodriguez, P. & Coscollá, M. (2026). Alignment-Free Tool for Assemblies and Reads in Genomic Surveillance of Tuberculosis. Emerging Infectious Diseases, 32(11). 10.3201/EID3211.261074 |
| Doi | 10.3201/EID3211.261074 |
| Publication Date | Nov 2026 |
| Publication Type | Article |
| Ontology | Genomics, Genome Sequencing, Genomic surveillance |
| Researchers | Mireia Coscolla Devis, Paula Ruiz Rodríguez |
| Research Groups | |
| Tools |