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Emerging human health concerns from chronic exposure to pesticide mixtures

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Distribution of y chromosomal STRs loci in Mayan and Mestizo populations from Guatemala

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Modulation of the endogenous antioxidants paraoxonase-1 and urate by pesticide exposure and genetic variants of xenobiotic-metabolizing enzymes

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Activity and determinants of cholinesterases and paraoxonase-1 in blood of workers exposed to non-cholinesterase inhibiting pesticides

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Placental DNA methylation signatures of maternal smoking during pregnancy and potential impacts on fetal growth

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A meta-analysis of pre-pregnancy maternal body mass index and placental DNA methylation identifies 27 CpG sites with implications for mother-child health

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Evaluation of Polyphenol Intake in Pregnant Women from South-Eastern Spain and the Effect on Anthropometric Measures at Birth and Gestational Age

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Transcriptomic profiling unveils novel therapeutic options for drug-resistant temporal lobe epilepsy

researcher

Antonio Gómez Martín

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Enrichment of Artemia nauplii in essential fatty acids with different types of liposomes and their use in the rearing of gilthead sea bream (Sparus aurata) larvae

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Differential metabolic and gene expression profile of juvenile common dentex (Dentex dentex L.) and gilthead sea bream (Sparus aurata L.) in relation to redox homeostasis

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Bacteria associated with winter mortalities in laboratory-reared common dentex (Dentex dentex L.)

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Differential tissue expression of uncoupling proteins in gilthead sea bream (Sparus aurata L): Lessons from UCP1 and UCP3 in fish

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Confinement exposure induces glucose regulated protein 75 (GRP75/mortalin/mtHsp70/PBP74/HSPA9B) in the hepatic tissue of gilthead sea bream (Sparus aurata L.)

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The time course of fish oil wash-out follows a simple dilution model in gilthead sea bream (Sparus aurata L.) fed graded levels of vegetable oils

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Gene expression survey of mitochondrial uncoupling proteins (UCP1/UCP3) in gilthead sea bream (Sparus aurata L.)

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Molecular characterization and expression analysis of six peroxiredoxin paralogous genes in gilthead sea bream (Sparus aurata): Insights from fish exposed to dietary, pathogen and confinement stressors

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Modelling the predictable effects of dietary lipid sources on the fillet fatty acid composition of one-year-old gilthead sea bream (Sparus aurata L.)

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Feed restriction up-regulates uncoupling protein 3 (UCP3) gene expression in heart and red muscle tissues of gilthead sea bream (Sparus aurata L.) New insights in substrate oxidation and energy expenditure

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Dietary oils mediate cortisol kinetics and the hepatic mRNA expression profile of stress-responsive genes in gilthead sea bream (Sparus aurata) exposed to crowding stress. Implications on energy homeostasis and stress susceptibility

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Deep sequencing for de novo construction of a marine fish (Sparus aurata) transcriptome database with a large coverage of protein-coding transcripts

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Tissue-specific gene expression and functional regulation of uncoupling protein 2 (UCP2) by hypoxia and nutrient availability in gilthead sea bream (Sparus aurata): implications on the physiological significance of UCP1-3 variants

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Metabolic and transcriptional responses of gilthead sea bream (Sparus aurata L.) to environmental stress: New insights in fish mitochondrial phenotyping

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Effects of a silver nanomaterial on cellular organelles and time course of oxidative stress in a fish cell line (PLHC-1)

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Tissue-specific gene expression and fasting regulation of sirtuin family in gilthead sea bream (Sparus aurata)

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Negligible cytotoxicity induced by different titanium dioxide nanoparticles in fish cell lines

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Induction of EROD and BFCOD activities in tissues of barbel (Barbus callensis) from a water reservoir in Algeria

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Fish cell lines as a tool for the ecotoxicity assessment and ranking of engineered nanomaterials

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Gene expression profiling of whole blood cells supports a more efficient mitochondrial respiration in hypoxia-challenged gilthead sea bream (Sparus aurata)

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Acute hazard of biocides for the aquatic environmental compartment from a life-cycle perspective

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Preparation of feed with metal oxide nanoparticles for nanomaterial dietary exposure to fish and use in OECD TG 305

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VKORC1 single nucleotide polymorphisms in rodents in Spain

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New Genes Involved in Osmotic Stress Tolerance in Saccharomyces cerevisiae

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Targeted exome sequencing of Krebs cycle genes reveals candidate cancer predisposing mutations in pheochromocytomas and paragangliomas

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Gain-of-function mutations in DNMT3A in patients with paraganglioma

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The Major Origin of Seedless Grapes Is Associated with a Missense Mutation in the MADS-Box Gene VviAGL11

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passport-data-sylv.txt

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genotypes_sylvestris.fam

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genotypes_SYLV_OUT.ped

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genotypes_SYLV_OUT.map

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README.txt

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A dataset of 9.896 single nuclear polymorphisms for 112 wild grapes, obtained with the GrapeReSeq 18K Vitis chip

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WeReview: CRISPR Tools—Live Repository of Computational Tools for Assisting CRISPR/Cas Experiments

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Hsa‐miR‐139‐5p is a prognostic thyroid cancer marker involved in HNRNPF‐mediated alternative splicing

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VviUCC1 Nucleotide Diversity, Linkage Disequilibrium and Association with Rachis Architecture Traits in Grapevine

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MYB transcription factors drive evolutionary innovations in Arabidopsis fruit trichome patterning

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Chronological and biological aging of the human left ventricular myocardium: Analysis of microRNAs contribution

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Spatial control of potato tuberization by the TCP transcription factor BRANCHED1b

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Genomic and immune landscape Of metastatic pheochromocytoma and paraganglioma

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Variation and plasticity in life-history traits and fitness of wild Arabidopsis thaliana populations are not related to their genotypic and ecological diversity

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The trichome pattern diversity of Cardamine shares genetic mechanisms with Arabidopsis but differs in environmental drivers

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Genome resequencing and custom genotyping elucidates the origin and dissemination history of an emblematic grapevine cultivar, ‘Tempranillo Tinto’

service unit

Bioinformatics Service at CBM

The CBMSO Bioinformatics Service originated from the Bioinformatics Unit established by Angel Ramirez Ortiz around...

service unit

Cellular, Molecular and Bioinformatics Service at ICVV

We provide flexible, end-to-end bioinformatics support across genomics, transcriptomics (RNA-seq, scRNA-seq), metataxonomics, and structural bioinform...

research line

Ecology and Biodiversity of fungi

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Evaluation of secondary structure of proteins from uv circular dichroism spectra using an unsupervised learning neural network

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A resolution of the chemotactic wave paradox

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Spatial dynamics of a model for prebiotic evolution

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Preface

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Compartimentation in replicator models

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Tubulin secondary structure analysis, limited proteolysis sites, and homology to FtsZ

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A prediction of DDP IV/CD26 domain structure from a physico-chemical investigation of dipeptidyl peptidase IV (CD26) from human seminal plasma

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Changes in microtubule protofilament number induced by taxol binding to an easily accessible site: Internal microtubule dynamics

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Using Situs for the registration of protein structures with low-resolution bead models from x-ray solution scattering

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Modeling tricks and fitting techniques for multiresolution structures

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Multi-resolution contour-based fitting of macromolecular structures

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Conformational flexibility of bacterial RNA polymerase

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Visualization of DNA-induced conformational changes in the DNA repair kinase DNA-PKcs

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Structure and function of the transcription elongation factor GreB bound to bacterial RNA polymerase

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Mega-Dalton biomolecular motion captured from electron microscopy reconstructions

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Fast rotational matching of rigid bodies by fast Fourier transform acceleration of five degrees of freedom

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Topology representing neural networks reconcile biomolecular shape, structure, and dynamics

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Predictions of protein flexibility: First-order measures

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Thorough Validation of Protein Normal Mode Analysis: A Comparative Study with Essential Dynamics

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Insights into Molecular Plasticity of Choline Binding Proteins (Pneumococcal Surface Proteins) by SAXS

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Grid multi-resolution docking

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Divergent Substrate-Binding Mechanisms Reveal an Evolutionary Specialization of Eukaryotic Prefoldin Compared to Its Archaeal Counterpart

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DFprot: A webtool for predicting local chain deformability

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ADP_EM: Fast exhaustive multi-resolution docking for high-throughput coverage

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Architecture of the Pontin/Reptin Complex, Essential in the Assembly of Several Macromolecular Complexes

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Protein shape and assembly studied with X-ray solution scattering: Fundaments and practice

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Plasmid replication initiator RepB forms a hexamer reminiscent of ring helicases and has mobile nuclease domains

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FRODOCK: A new approach for fast rotational protein-protein docking

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In memoriam. Angel Ramírez Ortiz (1966-2008).

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End-to-end cache system for grid computing: Design and efficiency analysis of a high-throughput bioinformatic docking application

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Approaching elastic network models to molecular dynamics flexibility

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iMod: Multipurpose normal mode analysis in internal coordinates

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Targeting the assembly of bacterial cell division protein FtsZ with small molecules

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Spinor product computations for protein conformations

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Normal mode analysis of molecular motions in curvilinear coordinates on a non-Eckart body-frame: An application to protein torsion dynamics

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Modeling Macromolecular Flexibility with Normal Mode Analysis in Internal Coordinates

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Curvilinear dynamics of protein complexes

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Synthetic inhibitors of bacterial cell division targeting the GTP-binding site of FtsZ

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Random coordinate descent with spinor-matrices and geometric filters for efficient loop closure

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IMODFIT: Efficient and robust flexible fitting based on vibrational analysis in internal coordinates

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Formation of an intricate helical bundle dictates the assembly of the 26S proteasome Lid

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Exploring large macromolecular functional motions on clusters of multicore processors

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Exploring Macromolecular Machine Motions

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Understanding nucleotide-regulated FtsZ filament dynamics and the monomer assembly switch with large-scale atomistic simulations

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Structural basis for selective recognition of endogenous and microbial polysaccharides by macrophage receptor SIGN-R1