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New insight into the SSC8 genetic determination of fatty acid composition in pigs


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KIT and melanoma predisposition in pigs: sequence variants and association analysis


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KITand melanoma predisposition in pigs: sequence variants and association analysis


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Evaluating the contribution of genetics and familial shared environment to common disease using the UK Biobank


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Direct and maternal additive effects are not the main determinants of Iberian piglet perinatal mortality


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Verificación racial de jamones y paletas Ibéricos comercializados en supermercados españoles


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Programa de selección genética enfocada en la calidad de cerdos Ibéricos puros de montanera


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Using genome wide association studies to identify common QTL regions in three different genetic backgrounds based on Iberian pig breed


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Evaluating Protocols for Porcine Faecal Microbiome Recollection, Storage and DNA Extraction: from the Farm to the Lab


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Diversity across major and candidate genes in European local pig breeds


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Identification of Candidate Genes and Regulatory Factors Underlying Intramuscular Fat Content Through Longissimus Dorsi Transcriptome Analyses in Heavy Iberian Pigs


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Genomic diversity, linkage disequilibrium and selection signatures in European local pig breeds assessed with a high density SNP chip


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Association between the pig genome and its gut microbiota composition


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Genome‐wide detection of copy number variants in European autochthonous and commercial pig breeds by whole‐genome sequencing of DNA pools identified breed‐characterising copy number states


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Describing variability in pig genes involved in coronavirus infections: towards a One Health perspective in conservation of animal genetic resources


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Development of a 64 SNV panel for breed authentication in Iberian pigs and their derived meat products


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Differences in the Loin Tenderness of Iberian Pigs Explained through Dissimilarities in Their Transcriptome Expression Profile


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Genetic parameter estimation and gene association analyses for meat quality traits in open‐air free‐range Iberian pigs


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Whole-genome sequencing of European autochthonous and commercial pig breeds allows the detection of signatures of selection for adaptation of genetic resources to different breeding and production systems


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Consequences of a low protein diet on the liver and longissimus dorsi transcriptome of Duroc x Iberian crossbred pigs


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Runs of homozygosity provide a genome landscape picture of inbreeding and genetic history of European autochthonous and commercial pig breeds


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Muscle Transcriptome Analysis Reveals Molecular Pathways Related to Oxidative Phosphorylation, Antioxidant Defense, Fatness and Growth in Mangalitsa and Moravka Pigs


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Use of NIRS for the assessment of meat quality traits in open-air free-range Iberian pigs


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Different HCV Exposure Drives Specific miRNA Profile in PBMCs of HIV Patients


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SNP discovery and association study for growth, fatness and meat quality traits in Iberian crossbred pigs


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HCV eradication with DAAs differently affects HIV males and females: A whole miRNA sequencing characterization


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Genetic diversity and population structure of six autochthonous pig breeds from Croatia, Serbia, and Slovenia


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Admixture and breed traceability in European indigenous pig breeds and wild boar using genome-wide SNP data


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Understanding the role of myoglobin content in Iberian pigs fattened in an extensive system through analysis of the transcriptome profile


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Dynamics of HIV Reservoir and HIV-1 Viral Splicing in HCV-Exposed Individuals after Elimination with DAAs or Spontaneous Clearance


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Design of a low-density SNP panel for intramuscular fat content and fatty acid composition of backfat in free-range Iberian pigs


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Different Effect of Vitamin E or Hydroxytyrosol Supplementation to Sow’s Diet on Oxidative Status and Performances of Weaned Piglets


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Maternal Supplementation of Vitamin E or Its Combination with Hydroxytyrosol Increases the Gut Health and Short Chain Fatty Acids of Piglets at Weaning


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Interrelation between gut microbiota, SCFA, and fatty acid composition in pigs


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Long-Term Effect of Maternal Antioxidant Supplementation on the Lipid Profile of the Progeny According to the Sow’s Parity Number


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Correction: Gómez et al. Long-Term Effect of Maternal Antioxidant Supplementation on the Lipid Profile of the Progeny According to the Sow’s Parity Number. Antioxidants 2024, 13, 379


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Short- But Not Long-Term Effects of Creep Feeding Provided to Suckling Piglets


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Assessment of Heterozygosity in European Local and Cosmopolitan Pig Populations


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Skin Aerosolization Predominance in a Pig Farm


tool

CODfinder


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Analysis of the relationship between coexpression domains and chromatin 3D organization


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TBL1 is required for the mesenchymal phenotype of transformed breast cancer cells


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The Cornelia de Lange Syndrome-associated factor NIPBL interacts with BRD4 ET domain for transcription control of a common set of genes


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TGFβ promotes widespread enhancer chromatin opening and operates on genomic regulatory domains


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The metabesity factor HMG20A potentiates astrocyte survival and reactive astrogliosis preserving neuronal integrity


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Human prefoldin modulates co-transcriptional pre-mRNA splicing


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Co-transcriptional splicing efficiency is a gene-specific feature that can be regulated by TGFβ


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TGF-β-Upregulated Lnc-Nr6a1 Acts as a Reservoir of miR-181 and Mediates Assembly of a Glycolytic Complex


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The high mobility group protein HMG20A cooperates with the histone reader PHF14 to modulate TGFβ and Hippo pathways


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SENP7 overexpression protects cancer cells from oxygen and glucose deprivation and associates with poor prognosis in colon cancer


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Metabolic reprogramming by Acly inhibition using SB-204990 alters glucoregulation and modulates molecular mechanisms associated with aging


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SWI/SNF-dependent genes are defined by their chromatin landscape


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Serpine1 mRNA confers mesenchymal characteristics to the cell and promotes CD8+ T cells exclusion from colon adenocarcinomas


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SARS-CoV-2 E protein interacts with BRD2 and BRD4 SEED domains and alters transcription in a different way than BET inhibition


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HMCES corrupts replication fork stability during base excision repair in homologous recombination-deficient cells


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Differential expression and co-expression reveal cell types relevant to genetic disorder phenotypes


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Metataxonomic analysis reveals that the farming system has minimal effect on soil microbiome variation in cereal fields


project

ZiRO

Aceites renovables de impacto ambiental ZERO


project

Rob3D

Exploiting the tridimensional optimality of microbial metabolism towards the sustainable production of natural products


project

SAAMBA

Supplying Antitumor and Antiviral Molecules through Biotechnology Applied to Maine Bacteria


project

AMBIZIONE

Advanced Microbiome biotechnology zips ONE HEALTH


project

DeCYPher

Decipher cytochrome P450 enzymes (CYPs) by digital tools to produce flavonoids and terpenoids


project

PROMISEANG

Alternative PROteins from MIcrobial fermentation of non-conventional SEA sources for Next-Generation food, feed and non-food...


project

FLAVO-GREEN

Synthetic biology for sustainable development


tool

FLYCOP


tool

Golden Standard


research group

Molecular Ocean Lab


research line

Molecular Simulations and Design of Plastic-degrading enzymes


research line

Developing a DNA biofoundry towards the AI-guided exploration of microbial chemical space.

We are actively involved in the development of a DNA biofoundry (CNBio) that integrates advanced...


research line

System level analysis and designing microbial communities

The division of labor allows an expanded complexity and functionality in microorganisms. Guided by these...


research line

Understanding and exploiting the multioptimality of microbial metabolism

Microbial metabolism operates and evolves under the trade-off between two principles: optimality under one given...


research line

Increasing the completeness and scope of metabolic reconstructions

We are committed to building a niche-specific collection of standardised and highly reproducible metabolic models....


service unit

CNBio (CNB DNA Biofoundry)

CNB DNA Biofoundry (CNBIO) offers a comprehensive service for the design, construction, validation, and evolution...


researcher

Kholoud Mamdouh


project

Development of Computational Approaches for the characterization and functional annotation of long-non-coding RNA (Annot-lncRNA)


project

Integrative Analysis of TEDDY data to improve T1D diagnosis


project

Developing a European American NGS Network (DEANN)


project

Desarrollo de métodos estadísticos para la integración de múltiples datos ómicos y de secuenciación masiva


project

Understanding the functional role of alternative splicing in crop traits


project

Plataformas de apoyo a la investigación en ciencias y tecnologías de la salud de la convocatoria 2017 de la Acción Estratégica en Salud


project

Identification and modelling of molecular and cellular events of the immune response associated to the appearance of minimal hepatic encephalopathy in cirrhotic patients


project

SISTEMAS INTEGRADOS INTELIGENTES EN CITRICOS (CITRUS-SII)


project

Development of tools of new generation for gene expression data analysis and implementation in the improved GEPAS platform


project

Estudio de perfiles moleculares de expresión génica de pólipos con morfología serrada para la identificación de nuevos marcadores pronósticos de cáncer colorrectal


project

Pathomics: metabolomica e interactomica de la relacion huespedparasito


project

Pathogenomics: Redes transcripcionales controladoras de la virulencia en hongos filamentosos patógenos


project

Exploring novel genome-transcriptome relationships by next generation sequencing approaches


project

Secuenciación, genotipado y desarrollo de herramientas genómicas para la mejora de los cítricos (CITRUSEQ)


project

ANÁLISIS DE GEMELOS DISCORDANTES PARA INVESTIGAR LA CORRELACIÓN ENTRE ALTERACIONES EN EXPRESIÓN Y METILACIÓN DE DNA EN LUPUS ERITEMATOSO SISTÉMICO


project

GENÓMICA Y TRANSCRIPTÓMICA DE LAS RUTAS DE DETOXIFICACIÓN EN DROSOPHILA


project

Desarrollo de nuevos conceptos y herramientas bioinformáticas de nueva generación para la priorización de genes candidatos en enfermedades y la elaboración de las correspondientes estrategias terapéuticas


project

STATegra: User-driven Development of Statistical Methods for Experimental Planning, Data Gathering, and Integrative Analysis of Next Generation Sequencing, Proteomics and Metabolomics data


project

Computational methods for the integration of ChIP-seq, metabolomics and RNA-seq data to model chromatin metabolism


project

The Next Systems Biology: statistical methods for multiomics systems biology


project

Novel methods for new challenges in the analysis of high-throughput sequencing data (NOVELSEQ)


project

Development of multiomics methods for the integrative study of the Yeast Metabolic Cycle


project

Developing the Functional Iso-Transcriptomics framework


project

Facilitating knowledge exchange between microbiology and computer science students: a computationally intensive approach to discover new adaptation genes in extreme environment


project

Galaxy platform for integrative metabolomics and transcriptomics analysis


project

Genotype by Environment interaction analysis to understand mechanisms of T1D pathogenesis


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