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System level analysis and designing microbial communities

The division of labor allows an expanded complexity and functionality in microorganisms. Guided by these...

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Understanding and exploiting the multioptimality of microbial metabolism

Microbial metabolism operates and evolves under the trade-off between two principles: optimality under one given...

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Increasing the completeness and scope of metabolic reconstructions

We are committed to building a niche-specific collection of standardised and highly reproducible metabolic models....

service unit

CNBio (CNB DNA Biofoundry)

CNB DNA Biofoundry (CNBIO) offers a comprehensive service for the design, construction, validation, and evolution...

researcher

Kholoud Mamdouh

project

Development of Computational Approaches for the characterization and functional annotation of long-non-coding RNA (Annot-lncRNA)

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Integrative Analysis of TEDDY data to improve T1D diagnosis

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Developing a European American NGS Network (DEANN)

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Desarrollo de métodos estadísticos para la integración de múltiples datos ómicos y de secuenciación masiva

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Understanding the functional role of alternative splicing in crop traits

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Plataformas de apoyo a la investigación en ciencias y tecnologías de la salud de la convocatoria 2017 de la Acción Estratégica en Salud

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Identification and modelling of molecular and cellular events of the immune response associated to the appearance of minimal hepatic encephalopathy in cirrhotic patients

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SISTEMAS INTEGRADOS INTELIGENTES EN CITRICOS (CITRUS-SII)

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Development of tools of new generation for gene expression data analysis and implementation in the improved GEPAS platform

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Estudio de perfiles moleculares de expresión génica de pólipos con morfología serrada para la identificación de nuevos marcadores pronósticos de cáncer colorrectal

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Pathomics: metabolomica e interactomica de la relacion huespedparasito

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Pathogenomics: Redes transcripcionales controladoras de la virulencia en hongos filamentosos patógenos

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Exploring novel genome-transcriptome relationships by next generation sequencing approaches

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Secuenciación, genotipado y desarrollo de herramientas genómicas para la mejora de los cítricos (CITRUSEQ)

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ANÁLISIS DE GEMELOS DISCORDANTES PARA INVESTIGAR LA CORRELACIÓN ENTRE ALTERACIONES EN EXPRESIÓN Y METILACIÓN DE DNA EN LUPUS ERITEMATOSO SISTÉMICO

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GENÓMICA Y TRANSCRIPTÓMICA DE LAS RUTAS DE DETOXIFICACIÓN EN DROSOPHILA

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Desarrollo de nuevos conceptos y herramientas bioinformáticas de nueva generación para la priorización de genes candidatos en enfermedades y la elaboración de las correspondientes estrategias terapéuticas

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STATegra: User-driven Development of Statistical Methods for Experimental Planning, Data Gathering, and Integrative Analysis of Next Generation Sequencing, Proteomics and Metabolomics data

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Computational methods for the integration of ChIP-seq, metabolomics and RNA-seq data to model chromatin metabolism

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The Next Systems Biology: statistical methods for multiomics systems biology

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Novel methods for new challenges in the analysis of high-throughput sequencing data (NOVELSEQ)

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Development of multiomics methods for the integrative study of the Yeast Metabolic Cycle

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Developing the Functional Iso-Transcriptomics framework

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Facilitating knowledge exchange between microbiology and computer science students: a computationally intensive approach to discover new adaptation genes in extreme environment

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Galaxy platform for integrative metabolomics and transcriptomics analysis

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Genotype by Environment interaction analysis to understand mechanisms of T1D pathogenesis

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Critical role for alternative splicing in conferring risk for T1D

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Development of methods for transcript quantification and differential expression analysis using long-read sequencing technologies

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A Novel Antimicrobial Approach To Combat Huanglongbing

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Microbial Dark Matter

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Identifying the determinants of high protein content in seeds of Phaseolus

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Integración de datos multi-ómicos para la inferencia de modelos multi-capa de enfermedad

project

HubBCB: Conexion CSIC en Biología Computacional y Bioinformática

acf-field

CVN/CVA PDF File

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Import your Curriculum Vitae (FECYT CVN and CVA)

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Genomic approaches to postharvest biotic and abiotic stresses of Citrus fruit

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Spatial study of antioxidant enzymes, peroxidase and phenylalanine ammonia-lyase in the citrus fruit-Penicillium digitatum interaction

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Global Regulation of Genes in Citrus Fruit in Response to the Postharvest Pathogen Penicillium digitatum

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Effect of Heat-Conditioning Treatments on Quality and Phenolic Composition of 'Fortune' Mandarin Fruit

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Biochemical and molecular characterization of induced resistance against Penicillium digiratum in citrus fruit

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Transcriptomic profiling of citrus fruit peel tissues reveals fundamental effects of phenylpropanoids and ethylene on induced resistance

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Metabolite biodiversity in pepper (Capsicum) fruits of thirty-two diverse accessions: Variation in health-related compounds and implications for breeding

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Effect of high-temperature-conditioning treatments on quality, flavonoid composition and vitamin C of cold stored 'Fortune' mandarins

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Differential Tomato Transcriptomic Responses Induced by Pepino Mosaic Virus Isolates with Differential Aggressiveness

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Unravelling molecular responses to moderate dehydration in harvested fruit of sweet orange (Citrus sinensis L. Osbeck) using a fruit-specific ABA-deficient mutant

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The Tomato FRUITFULL Homologs TDR4/FUL1 and MBP7/FUL2 Regulate Ethylene-Independent Aspects of Fruit Ripening

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Genome sequence of the necrotrophic fungus Penicillium digitatum, the main postharvest pathogen of citrus

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Secondary Metabolites of Capsicum Species and Their Importance in the Human Diet

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Metabolomics and molecular marker analysis to explore pepper (Capsicum sp.) biodiversity

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Citrus phenylpropanoids and defence against pathogens. Part II: Gene expression and metabolite accumulation in the response of fruits to Penicillium digitatum infection

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Genetic mapping of semi-polar metabolites in pepper fruits (Capsicum sp.): towards unravelling the molecular regulation of flavonoid quantitative trait loci

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Irregular Distribution of Sharka (Plum Pox Virus) Symptoms in Peach Is Related to Differential Gene Expression Evidenced by RNA-Seq

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Identification and functional analysis of Penicillium digitatum genes putatively involved in virulence towards citrus fruit

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Genome, Transcriptome, and Functional Analyses of Penicillium expansum Provide New Insights Into Secondary Metabolism and Pathogenicity

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Gene Expression Analysis of Plum pox virus (Sharka) Susceptibility/Resistance in Apricot (Prunus armeniaca L.)

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Analysis of gene expression changes in peach leaves in response to Plum pox virus infection using RNA-Seq

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Molecular aspects in pathogen-fruit interactions: Virulence and resistance

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Inhibiting ethylene perception with 1-methylcyclopropene triggers molecular responses aimed to cope with cell toxicity and increased respiration in citrus fruits

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Identification of Loci Affecting Accumulation of Secondary Metabolites in Tomato Fruit of a Solanum lycopersicum x Solanum chmielewskii Introgression Line Population

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Genomic tools for developing markers for postharvest disease resistance in Rosaceae fruit crops

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Genome sequencing and secondary metabolism of the postharvest pathogen Penicillium griseofulvum

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De novo sequencing and detection of secondary metabolite gene clusters of Penicillium griseofulvum

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Transcriptomic Response of Resistant (PI613981-Malus sieversii) and Susceptible ("Royal Gala") Genotypes of Apple to Blue Mold (Penicillium expansum) Infection

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LED Blue Light-induced changes in phenolics and ethylene in citrus fruit: Implication in elicited resistance against Penicillium digitatum infection

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Identification and characterization of LysM effectors in Penicillium expansum

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Unravelling the contribution of the Penicillium expansum PeSte12 transcription factor to virulence during apple fruit infection

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Differential contribution of the two major polygalacturonases from Penicillium digitatum to virulence towards citrus fruit

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Functional Characterization of the alb1 Orthologue Gene in the Ochratoxigenic Fungus Aspergillus carbonarius (AC49 strain)

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Involvement of abscisic acid in the resistance of citrus fruit to Penicillium digitatum infection

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Identification of pathogenicity-related genes and the role of a subtilisin-related peptidase S8 (PePRT) in authophagy and virulence of Penicillium expansum on apples

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Functional and Pharmacological Analyses of the Role of Penicillium digitatum Proteases on Virulence

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Evaluation of the activity of the antifungal PgAFP protein and its producer mould against Penicillium spp postharvest pathogens of citrus and pome fruits

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Production of unpurified agar-based extracts from red seaweed Gelidium sesquipedale by means of simplified extraction protocols

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In-Depth Characterization of Bioactive Extracts from Posidonia oceanica Waste Biomass

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EFE-Mediated Ethylene Synthesis Is the Major Pathway in the Citrus Postharvest Pathogen Penicillium digitatum during Fruit Infection

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Elaborated regulation of griseofulvin biosynthesis in Penicillium griseofulvum and its role on conidiation and virulence

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Antifungal edible coatings containing Argentinian propolis extract and their application in raspberries

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Functional Role of Aspergillus carbonarius AcOTAbZIP Gene, a bZIP Transcription Factor within the OTA Gene Cluster

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Coordinated activation of the metabolic pathways induced by LED blue light in citrus fruit

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Securing fruit production: Opportunities from the elucidation of the molecular mechanisms of postharvest fungal infections

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Interrelation between ABA and phospholipases D, C and A2 in early responses of citrus fruit to Penicillium digitatum infection

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Ochratoxin A Defective Aspergillus carbonarius Mutants as Potential Biocontrol Agents

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Impact of the antifungal protein PgAFP on the proteome and patulin production of Penicillium expansum on apple-based medium

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Horizon scanning on microorganisms and their products obtained by new developments in biotechnology

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Exploring the Biocontrol Capability of Non-Mycotoxigenic Strains of Penicillium expansum

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Discovery and Transcriptional Profiling of Penicillium digitatum Genes That Could Promote Fungal Virulence during Citrus Fruit Infection

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Antimicrobial and antioxidant properties of water-soluble lignin extracts obtained from ozonation of Miscanthus giganteus and Vitis vinifera in a pilot-scale reactor

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Histone Methyltransferases AcDot1 and AcRmtA Are Involved in Growth Regulation, Secondary Metabolism, and Stress Response in Aspergillus carbonarius

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The role of Penicillium expansum histone deacetylases HosA and HosB in growth, development, and patulin production

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Studies on the production of fungal peroxidases in Aspergillus niger

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Expression of the Caldariomyces fumago chloroperoxidase in Aspergillus niger and characterization of the recombinant enzyme

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C-terminal propeptide of the Caldariomyces fumago chloroperoxidase: an intramolecular chaperone?

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Fungal peroxidases: molecular aspects and applications

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Filamentous fungi as cell factories for heterologous protein production

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Calnexin overexpression increases manganese peroxidase production in Aspergillus niger