research line

Machine Learning & Deep Learning in Biology

Developing and applying cutting-edge algorithms for biological data analysis and predictive modelling.

orcid publication

Effect of alternate feeding with a poor long-chain polyunsaturated fatty acid Artemia strain and a rich one for sea bass (Dicentrarchus labrax) and prawn (Penaeus kerathurus) larvae

orcid publication

Utilisation of Artemia cysts in marine larvae cultures: A model of quality evaluation

orcid publication

Some aspects of Artemia biology affected by cestode parasitism

orcid publication

Effects of temperature and oxygen tension on oxygen consumption rates of nauplii of different Artemia strains

orcid publication

Characterizing bisexual Artemia populations by isoelectric focusing

orcid publication

Comparison of two methods for measuring the rates of oxygen consumption of small aquatic animals (Artemia)

orcid publication

Comparative study of the effects of temperature, salinity and oxygen tension on the rates of oxygen consumption of nauplii of different strains of Artemia

orcid publication

Biogeography of the genus Artemia (Crustacea, Branchiopoda, Anostraca) in Spain

orcid publication

Effect of endosulfan pesticide on the oxygen consumption rates of nauplii of different Spanish strains of Artemia

orcid publication

The effects of temperature and oxygen tension (P(O2)) on the oxygen consumption rates of adults of different Artemia strains

orcid publication

Acute lethal toxicity of the organophosphorus pesticide chlorpyrifos to different species and strains of Artemia

orcid publication

Effect of parasitism on respiration rates of adults of different Artemia strains from Spain

orcid publication

Characterisation of cholinesterases and evaluation of the inhibitory potential of chlorpyrifos and dichlorvos to Artemia salina and Artemia parthenogenetica

orcid publication

Bioaccumulation of chlorpyrifos through an experimental food chain: Study of protein HSP70 as biomarker of sublethal stress in fish

orcid publication

Effect of dichlorvos on cholinesterase activity of the European sea bass (Dicentrarchus labrax)

orcid publication

Changes in antioxidant enzyme activities, fatty acid composition and lipid peroxidation in Daphnia magna during the aging process

orcid publication

Antioxidant enzyme activities and lipid peroxidation in the freshwater cladoceran Daphnia magna exposed to redox cycling compounds

orcid publication

Comparative toxicokinetics of cadmium in Artemia

orcid publication

Assessment of the efficacy of Artemia sp (Crustacea) cysts chorion as barrier to chlorpyrifos (organophosphorus pesticide) exposure. Effect on hatching and survival

orcid publication

Effects of dichlorvos aquaculture treatments on selected biomarkers of gilthead sea bream (Sparus aurata L.) fingerlings

orcid publication

Effect of sublethal concentrations of copper sulphate on seabream Sparus aurata fingerlings

orcid publication

Sublethal zinc exposure has a detrimental effect on reproductive performance but not on the cyst hatching success of Artemia parthenogenetica

orcid publication

Acute toxicity of dichlorvos to Aphanius iberus (Cuvier & Valenciennes, 1846) and its anti-cholinesterase effects on this species

orcid publication

Effect of ivermectin on the liver of gilthead sea bream Sparus aurata: A proteomic approach

orcid publication

Long-term effect of temperature on bioaccumulation of dietary metals and metallothionein induction in Sparus aurata

orcid publication

Characterization of type "B" esterases and hepatic CYP450 isoenzimes in Senegalese sole for their further application in monitoring studies

orcid publication

Characterization of the organic contamination pattern of a hyper-saline ecosystem by rapid screening using gas chromatography coupled to high-resolution time-of-flight mass spectrometry

orcid publication

A revision of Artemia biodiversity in Macaronesia

orcid publication

Proteomic evaluation of potentiated sulfa treatment on gilthead sea bream (Sparus aurata L.) liver

orcid publication

Enrichment of Artemia metanauplii in phospholipids and essential fatty acids as a diet for common octopus (Octopus vulgaris) paralarvae

orcid publication

Enriched on-grown Artemia metanauplii actively metabolise highly unsaturated fatty acid-rich phospholipids

orcid publication

Distribution and depletion of sulfadiazine after a multiple per os dosing in gilthead sea bream (Sparus aurata) fed two different diets

orcid publication

Comparative analysis of selected biomarkers and pesticide sensitivity in juveniles of Solea solea and Solea senegalensis

orcid publication

Xenobiotic metabolism modulation after long-term temperature acclimation in juveniles of Solea senegalensis

orcid publication

Aquatic pollution may favor the success of the invasive species A. franciscana

orcid publication

Time-dependent effects of polystyrene nanoparticles in brine shrimp Artemia franciscana at physiological, biochemical and molecular levels

orcid publication

Effect of short-term exposure to fluorescent red polymer microspheres on Artemia franciscana nauplii and juveniles

orcid publication

Surface-Functionalized Polystyrene Nanoparticles Alter the Transmembrane Potential via Ion-Selective Pores Maintaining Global Bilayer Integrity

project

Computational identification of small signalling peptides

Project on the prediction of small signalling peptides in plants developing a web tool from...

project

TRANSCEND-ID. Approches intégratives d’Intelligence Artificielle et de la biologie pour la modélisation de l'inflammation chronique

Structuring project: Integrative approaches in mathematics, computer science, and biology for the modelling of chronic...

project

Charting the shared basis of Cancer, Autoimmune, and Cardiovascular diseases using multi-scale Topology and Optimal Transport

Research on polygenic inheritance in cancer, inflammatory, and cardiovascular diseases using topological deep learning and...

project

Decoding vector-induced gene regulation in plant-insect-virus causal diagrams

Project on the characterisation of TYLCV virus manifolds in tomato plant using spatial transcriptomics and...

tool

GeoTop

Lipschitz-Killing Curvatures and Topological Data Analysis method for Machine Learning Image Classification (computer vision)!

tool

microSTASIS

The toolkit ‘µSTASIS’, or microSTASIS, has been developed for the stability analysis of microbiota in...

orcid publication

GeoTop: Advancing Image Classification with Geometric-Topological Analysis

We present GeoTop, a novel framework that synergises Topological Data Analysis and Lipschitz-Killing Curvatures to...

project

Identification of genetic and metabolic components of the gut microbiota and dietary strategies for preventing non-communicable diseases.

The general aim of the research project is to develop innovative strategies based on probiotics...

project

Functional mimicry of the human dipeptidyl peptidase-4 activity by the gut microbes and dietary strategies for its inhibition – MIMICROBES

Human microbiome research is fast-growing due to the advances in omics technologies permitting the disentangling...

research line

Diet-host-microbe interactions in health and disease

research group

Bioinformatics, Computational Biology and Data Science

orcid publication

From Bacterial Genomics to Human Health

orcid publication

Multi-locus and long amplicon sequencing approach to study microbial diversity at species level using the MinION™ portable nanopore sequencer

orcid publication

Gut microbiota DPP4-like enzymes are increased in type-2 diabetes and contribute to incretin inactivation

orcid publication

Results of the GEP-ISFG collaborative study on two Y-STRs tetraplexes: GEPY I (DYS461, GATA C4, DYS437 and DYS438) and GEPY II (DYS460, GATA A10, GATA H4 and DYS439)

orcid publication

Population data of new Y-chromosome STRs GATA C4, DYS438, DYS437, GATA A7.2, GATA H4, DYS439 and GATA A10 in males from Colombia

orcid publication

Allelic frequencies at 12 STR loci in Colombian population

orcid publication

Population analysis from 12 microsatellite loci reveled by silver stain and assisted by computer software

orcid publication

Structure-Function Analysis of Escherichia coli MnmG (GidA), a Highly Conserved tRNA-Modifying Enzyme

orcid publication

Considerations to Improve Functional Annotations in Biological Databases

orcid publication

YibK is the 2 '-O-methyltransferase TrmL that modifies the wobble nucleotide in Escherichia coli tRNA(Leu) isoacceptors

orcid publication

Bioinformatics in Colombia: State of the art and perspectives,Bioinformática en Colombia: Presente y futuro de la investigación biocomputacional

orcid publication

The Escherichia coli RlmN methyltransferase is a dual-specificity enzyme that modifies both rRNA and tRNA and controls translational accuracy

orcid publication

Regulation of expression and catalytic activity of Escherichia coli RsmG methyltransferase

orcid publication

Enzymology of tRNA modification in the bacterial MnmEG pathway

orcid publication

A practical guide for the computational selection of residues to be experimentally characterized in protein families

orcid publication

Detection of Transient Bacteraemia following Dental Extractions by 16S rDNA Pyrosequencing: A Pilot Study

orcid publication

iTRAQ, the high throughput data analysis of proteins to understand immunologic expression in insect

orcid publication

Microbiota diversity and gene expression dynamics in human oral biofilms

orcid publication

Impairing methylations at ribosome RNA, a point mutation-dependent strategy for aminoglycoside resistance: The rsmG case

orcid publication

Evolutionary and sequence-based relationships in bacterial AdoMet-dependent non-coding RNA methyltransferases

orcid publication

Development of Quantitative Proteomics Using iTRAQ Based on the Immunological Response of Galleria mellonella Larvae Challenged with Fusarium oxysporum Microconidia

orcid publication

Streptococcus dentisani sp. nov., a novel member of the mitis group (vol 64, pg 60, 2014)

orcid publication

Streptococcus dentisani sp nov., a novel member of the mitis group

orcid publication

Pangenome-wide and molecular evolution analyses of the Pseudomonas aeruginosa species

orcid publication

Species-level resolution of 16S rRNA gene amplicons sequenced through the MinION (TM) portable nanopore sequencer

orcid publication

Genome Structure of the Symbiont Bifidobacterium pseudocatenulatum CECT 7765 and Gene Expression Profiling in Response to Lactulose-Derived Oligosaccharides

orcid publication

Targeting the Microbiota: Considerations for Developing Probiotics as Functional Foods

orcid publication

Lactobacillus fermentum CRL1446 Ameliorates Oxidative and Metabolic Parameters by Increasing Intestinal Feruloyl Esterase Activity and Modulating Microbiota in Caloric-Restricted Mice

orcid publication

Impact of dietary fiber and fat on gut microbiota re-modeling and metabolic health

orcid publication

Gut microbiota, diet, and obesity-related disorders-the good, the bad, and the future challenges

orcid publication

The glycolytic versatility of Bacteroides uniformis CECT 7771 and Its genome response to oligo and polysaccharides

orcid publication

Bifidobacterium CECT 7765 modulates early stress-induced immune, neuroendocrine and behavioral alterations in mice.

orcid publication

Gut microbiota trajectory in early life may predict development of celiac disease

orcid publication

Increased prevalence of pathogenic bacteria in the gut microbiota of infants at risk of developing celiac disease: The PROFICEL study

orcid publication

Plant sterols and human gut microbiota relationship: An in vitro colonic fermentation study

orcid publication

The potential role of the Dipeptidyl peptidase-4-like activity from the gut microbiota on the Host Health

orcid publication

Bacillus subtilis exhibits MnmC-like tRNA modification activities

orcid publication

Bifidobacterium pseudocatenulatum CECT 7765 supplementation improves inflammatory status in insulin-resistant obese children

orcid publication

Towards microbiome-informed dietary recommendations for promoting metabolic and mental health: Opinion papers of the MyNewGut project

orcid publication

Pre-obese children’s dysbiotic gut microbiome and unhealthy diets may predict the development of obesity

orcid publication

Agarose-based freeze-dried capsules prepared by the oil-induced biphasic hydrogel particle formation approach for the protection of sensitive probiotic bacteria

orcid publication

Nutritional interest of dietary fiber and prebiotics in obesity: Lessons from the MyNewGut consortium

orcid publication

A Multi-omics Approach to Unraveling the Microbiome-Mediated Effects of Arabinoxylan Oligosaccharides in Overweight Humans

orcid publication

Dietary fat, the gut microbiota, and metabolic health – a systematic review conducted within the MyNewGut project

orcid publication

Arabinoxylan oligosaccharides and polyunsaturated fatty acid effects on gut microbiota and metabolic markers in overweight individuals with signs of metabolic syndrome: A randomized cross-over trial

orcid publication

Safety Assessment of Bacteroides Uniformis CECT 7771, a Symbiont of the Gut Microbiota in Infants

orcid publication

Depletion of Blautia Species in the Microbiota of Obese Children Relates to Intestinal Inflammation and Metabolic Phenotype Worsening

orcid publication

Breast-Milk Microbiota Linked to Celiac Disease Development in Children: A Pilot Study From the PreventCD Cohort

orcid publication

The effect of inulin and resistant maltodextrin on weight loss during energy restriction: a randomised, placebo-controlled, double-blinded intervention

orcid publication

Study protocol of the Bergen brain-gut-microbiota-axis study A prospective case-report characterization and dietary intervention study to evaluate the effects of microbiota alterations on cognition and anatomical and functional brain connectivity in patients with irritable bowel syndrome