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Enriched on-grown Artemia metanauplii actively metabolise highly unsaturated fatty acid-rich phospholipids

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Distribution and depletion of sulfadiazine after a multiple per os dosing in gilthead sea bream (Sparus aurata) fed two different diets

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Comparative analysis of selected biomarkers and pesticide sensitivity in juveniles of Solea solea and Solea senegalensis

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Xenobiotic metabolism modulation after long-term temperature acclimation in juveniles of Solea senegalensis

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Aquatic pollution may favor the success of the invasive species A. franciscana

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Time-dependent effects of polystyrene nanoparticles in brine shrimp Artemia franciscana at physiological, biochemical and molecular levels

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Effect of short-term exposure to fluorescent red polymer microspheres on Artemia franciscana nauplii and juveniles

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Surface-Functionalized Polystyrene Nanoparticles Alter the Transmembrane Potential via Ion-Selective Pores Maintaining Global Bilayer Integrity

project

Computational identification of small signalling peptides

Project on the prediction of small signalling peptides in plants developing a web tool from...

project

TRANSCEND-ID. Approches intégratives d’Intelligence Artificielle et de la biologie pour la modélisation de l'inflammation chronique

Structuring project: Integrative approaches in mathematics, computer science, and biology for the modelling of chronic...

project

Charting the shared basis of Cancer, Autoimmune, and Cardiovascular diseases using multi-scale Topology and Optimal Transport

Research on polygenic inheritance in cancer, inflammatory, and cardiovascular diseases using topological deep learning and...

project

Decoding vector-induced gene regulation in plant-insect-virus causal diagrams

Project on the characterisation of TYLCV virus manifolds in tomato plant using spatial transcriptomics and...

tool

GeoTop

Lipschitz-Killing Curvatures and Topological Data Analysis method for Machine Learning Image Classification (computer vision)!

tool

microSTASIS

The toolkit ‘µSTASIS’, or microSTASIS, has been developed for the stability analysis of microbiota in...

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GeoTop: Advancing Image Classification with Geometric-Topological Analysis

We present GeoTop, a novel framework that synergises Topological Data Analysis and Lipschitz-Killing Curvatures to...

project

Identification of genetic and metabolic components of the gut microbiota and dietary strategies for preventing non-communicable diseases.

The general aim of the research project is to develop innovative strategies based on probiotics...

project

Functional mimicry of the human dipeptidyl peptidase-4 activity by the gut microbes and dietary strategies for its inhibition – MIMICROBES

Human microbiome research is fast-growing due to the advances in omics technologies permitting the disentangling...

research line

Diet-host-microbe interactions in health and disease

research group

Bioinformatics, Computational Biology and Data Science

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From Bacterial Genomics to Human Health

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Multi-locus and long amplicon sequencing approach to study microbial diversity at species level using the MinION™ portable nanopore sequencer

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Gut microbiota DPP4-like enzymes are increased in type-2 diabetes and contribute to incretin inactivation

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Results of the GEP-ISFG collaborative study on two Y-STRs tetraplexes: GEPY I (DYS461, GATA C4, DYS437 and DYS438) and GEPY II (DYS460, GATA A10, GATA H4 and DYS439)

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Population data of new Y-chromosome STRs GATA C4, DYS438, DYS437, GATA A7.2, GATA H4, DYS439 and GATA A10 in males from Colombia

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Allelic frequencies at 12 STR loci in Colombian population

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Population analysis from 12 microsatellite loci reveled by silver stain and assisted by computer software

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Structure-Function Analysis of Escherichia coli MnmG (GidA), a Highly Conserved tRNA-Modifying Enzyme

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Considerations to Improve Functional Annotations in Biological Databases

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YibK is the 2 '-O-methyltransferase TrmL that modifies the wobble nucleotide in Escherichia coli tRNA(Leu) isoacceptors

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Bioinformatics in Colombia: State of the art and perspectives,Bioinformática en Colombia: Presente y futuro de la investigación biocomputacional

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The Escherichia coli RlmN methyltransferase is a dual-specificity enzyme that modifies both rRNA and tRNA and controls translational accuracy

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Regulation of expression and catalytic activity of Escherichia coli RsmG methyltransferase

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Enzymology of tRNA modification in the bacterial MnmEG pathway

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A practical guide for the computational selection of residues to be experimentally characterized in protein families

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Detection of Transient Bacteraemia following Dental Extractions by 16S rDNA Pyrosequencing: A Pilot Study

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iTRAQ, the high throughput data analysis of proteins to understand immunologic expression in insect

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Microbiota diversity and gene expression dynamics in human oral biofilms

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Impairing methylations at ribosome RNA, a point mutation-dependent strategy for aminoglycoside resistance: The rsmG case

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Evolutionary and sequence-based relationships in bacterial AdoMet-dependent non-coding RNA methyltransferases

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Development of Quantitative Proteomics Using iTRAQ Based on the Immunological Response of Galleria mellonella Larvae Challenged with Fusarium oxysporum Microconidia

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Streptococcus dentisani sp. nov., a novel member of the mitis group (vol 64, pg 60, 2014)

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Streptococcus dentisani sp nov., a novel member of the mitis group

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Pangenome-wide and molecular evolution analyses of the Pseudomonas aeruginosa species

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Species-level resolution of 16S rRNA gene amplicons sequenced through the MinION (TM) portable nanopore sequencer

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Genome Structure of the Symbiont Bifidobacterium pseudocatenulatum CECT 7765 and Gene Expression Profiling in Response to Lactulose-Derived Oligosaccharides

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Targeting the Microbiota: Considerations for Developing Probiotics as Functional Foods

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Lactobacillus fermentum CRL1446 Ameliorates Oxidative and Metabolic Parameters by Increasing Intestinal Feruloyl Esterase Activity and Modulating Microbiota in Caloric-Restricted Mice

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Impact of dietary fiber and fat on gut microbiota re-modeling and metabolic health

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Gut microbiota, diet, and obesity-related disorders-the good, the bad, and the future challenges

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The glycolytic versatility of Bacteroides uniformis CECT 7771 and Its genome response to oligo and polysaccharides

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Bifidobacterium CECT 7765 modulates early stress-induced immune, neuroendocrine and behavioral alterations in mice.

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Gut microbiota trajectory in early life may predict development of celiac disease

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Increased prevalence of pathogenic bacteria in the gut microbiota of infants at risk of developing celiac disease: The PROFICEL study

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Plant sterols and human gut microbiota relationship: An in vitro colonic fermentation study

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The potential role of the Dipeptidyl peptidase-4-like activity from the gut microbiota on the Host Health

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Bacillus subtilis exhibits MnmC-like tRNA modification activities

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Bifidobacterium pseudocatenulatum CECT 7765 supplementation improves inflammatory status in insulin-resistant obese children

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Towards microbiome-informed dietary recommendations for promoting metabolic and mental health: Opinion papers of the MyNewGut project

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Pre-obese children’s dysbiotic gut microbiome and unhealthy diets may predict the development of obesity

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Agarose-based freeze-dried capsules prepared by the oil-induced biphasic hydrogel particle formation approach for the protection of sensitive probiotic bacteria

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Nutritional interest of dietary fiber and prebiotics in obesity: Lessons from the MyNewGut consortium

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A Multi-omics Approach to Unraveling the Microbiome-Mediated Effects of Arabinoxylan Oligosaccharides in Overweight Humans

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Dietary fat, the gut microbiota, and metabolic health – a systematic review conducted within the MyNewGut project

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Arabinoxylan oligosaccharides and polyunsaturated fatty acid effects on gut microbiota and metabolic markers in overweight individuals with signs of metabolic syndrome: A randomized cross-over trial

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Safety Assessment of Bacteroides Uniformis CECT 7771, a Symbiont of the Gut Microbiota in Infants

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Depletion of Blautia Species in the Microbiota of Obese Children Relates to Intestinal Inflammation and Metabolic Phenotype Worsening

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Breast-Milk Microbiota Linked to Celiac Disease Development in Children: A Pilot Study From the PreventCD Cohort

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The effect of inulin and resistant maltodextrin on weight loss during energy restriction: a randomised, placebo-controlled, double-blinded intervention

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Study protocol of the Bergen brain-gut-microbiota-axis study A prospective case-report characterization and dietary intervention study to evaluate the effects of microbiota alterations on cognition and anatomical and functional brain connectivity in patients with irritable bowel syndrome

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Species- and strain-level assessment usingrrnlong-amplicons suggests donor’s influence on gut microbial transference via fecal transplants in metabolic syndrome subjects

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Microbial enterotypes beyond genus level: Bacteroides species as a predictive biomarker for weight change upon controlled intervention with arabinoxylan oligosaccharides in overweight subjects

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Gut microbiota profiles in critically ill patients, potential biomarkers and risk variables for sepsis

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Infusion of donor feces affects the gut-brain axis in humans with metabolic syndrome

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Bacteroides uniformis combined with fiber amplifies metabolic and immune benefits in obese mice

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Sex, Food, and the Gut Microbiota: Disparate Response to Caloric Restriction Diet with Fiber Supplementation in Women and Men

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Bacteroides uniformis CECT 7771 alleviates inflammation within the gut-adipose tissue axis involving TLR5 signaling in obese mice

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Holdemanella biformis improves glucose tolerance and regulates GLP‐1 signaling in obese mice

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Editorial: Remodeling Composition and Function of Microbiome by Dietary Strategies-Functional Foods Perspective

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The microbiota composition drives personalized nutrition: Gut microbes as predictive biomarkers for the success of weight loss diets

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Gut bless you: The microbiota-gut-brain axis in irritable bowel syndrome

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Assessment of human microbiota stability across longitudinal samples using iteratively growing-partitioned clustering

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Intestinal microbiota is modified in pediatric food protein–induced enterocolitis syndrome

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Species- and strain-level assessment using rrn long-amplicons suggests donor’s influence on gut microbial transference via fecal transplants in metabolic syndrome subjects

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Editorial: Contribution of the maternal microbiome to offspring health

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Comparative Binding Study of Gliptins to Bacterial DPP4-like Enzymes for the Treatment of Type 2 Diabetes Mellitus (T2DM)

project

Development of HPC and AI-Based Tools for Large-Scale Spatial Transcriptomics and Single-Cell Data Integration

In today’s science, data processing technologies play an increasingly crucial role, driven by technological advances...

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Novel dimensionality reduction method, Taelcore, enhances lung transplantation risk prediction

In this work, we present a new approach to predict the risk of acute cellular rejection (ACR)...

tool

CoMM-BIP

A Contrastive Multi-Modal learning model with Biologically Informed Priors!

tool

TaelCore

A Python library for dimensional reduction using topological auto-encoders

tool

 S²-PepAnalyst

Our web tool, S2-PepAnalyst, is designed to predict SSPs from input sequences or uploaded files (FASTA/FA/TXT)...

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Topological Machine Learning

Exploring topological and geometric approaches to unveil robust patterns in high-dimensional multi-omics data.

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Application of Deep Learning to Biomedical Image Analysis

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Development of Computational Tools for Spatial Transcriptomics Data Analysis

research line

Application of Machine Learning for Cancer Biomarker Discovery

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The cellular growth rate controls overall mRNA turnover, and modulates either transcription or degradation rates of particular gene regulons

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Pluripotency factors regulate the onset of Hox cluster activation in the early embryo

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Epigenomics and Transcriptomics of Systemic Sclerosis CD4+ T cells reveal Long Range Dysregulation of Key Inflammatory Pathways mediated by disease-associated Susceptibility Loci

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HDAC6 regulates expression of the oncogenic driver EWSR1-FLI1 through theEWSR1promoter in Ewing sarcoma

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Evidence for a role of phenotypic mutations in virus adaptation

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Single-Cell Atlas of Common Variable Immunodeficiency reveals germinal center-associated epigenetic dysregulation in B cell responses