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orcid publication

Differential Modulation of Quorum Sensing Signaling through QslA in Pseudomonas aeruginosa Strains PAO1 and PA14


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Building gene regulatory networks from scATAC-seq and scRNA-seq using Linked Self Organizing Maps


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STATegra, a comprehensive multi-omics dataset of B-cell differentiation in mouse


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Making multi-omics data accessible to researchers


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Mip6 binds directly to the Mex67 UBA domain to maintain low levels of Msn2/4 stress‐dependent mRNAs


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A network approach to elucidate and prioritize microbial dark matter in microbial communities


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MultiBaC: A strategy to remove batch effects between different omic data types


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Transcriptional differences for COVID-19 Disease Map genes between males and females indicate a different basal immunophenotype relevant to the disease


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Harmonization of quality metrics and power calculation in multi-omic studies


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Assessment of unconventional antimicrobial compounds for the control of ‘Candidatus Liberibacter asiaticus’, the causative agent of citrus greening disease


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A multi-omics dataset of heat-shock response in the yeast RNA binding protein Mip6


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Padhoc: a computational pipeline for pathway reconstruction on the fly


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MirCure: a tool for quality control, filter and curation of microRNAs of animals and plants


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Multi-omic analysis unveils biological pathways in peripheral immune system associated to minimal hepatic encephalopathy appearance in cirrhotic patients


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A multi-omic study for uncovering molecular mechanisms associated with hyperammonemia-induced cerebellar function impairment in rats


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STATegra: Multi-Omics Data Integration – A Conceptual Scheme With a Bioinformatics Pipeline


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Ozone sensitivity of diverse maize genotypes is associated with differences in gene regulation, not gene content


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Acorde: unraveling functionally-interpretable networks of isoform co-usage from single cell data


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Precise transcriptional control of cellular quiescence by BRAVO/WOX5 complex in Arabidopsis roots


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Undisclosed, unmet and neglected challenges in multi-omics studies


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Global Methylome Scores Correlate with Histological Subtypes of Colorectal Carcinoma and Show Different Associations with Common Clinical and Molecular Features


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acorde unravels functionally interpretable networks of isoform co-usage from single cell data


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PaintOmics 4: new tools for the integrative analysis of multi-omics datasets supported by multiple pathway databases


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Variation in leaf transcriptome responses to elevated ozone corresponds with physiological sensitivity to ozone across maize inbred lines


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MAMBA: a model-driven, constraint-based multiomic integration method


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New roles for AP-1/JUNB in cell cycle control and tumorigenic cell invasion via regulation of cyclin E1 and TGF-β2


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SQANTI-SIM: a simulator of controlled transcript novelty for lrRNA-seq benchmark


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MORE interpretable multi-omic regulatory networks to characterize phenotypes


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Nucleotide-level distance metrics to quantify alternative splicing implemented in TranD


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scMaSigPro: differential expression analysis along single-cell trajectories


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Biological databases in the age of generative artificial intelligence


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Profiling the epigenome using long-read sequencing


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MOSim bulk and single cell multi layer regulatory network simulator


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Transcriptomics in the era of long-read sequencing


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Quality assessment of long read data in multisample lrRNA-seq experiments using SQANTI-reads


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Notable challenges posed by long-read sequencing for the study of transcriptional diversity and genome annotation


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Evaluation of strategies for evidence-driven genome annotation using long-read RNA-seq


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orcid publication

Optimizing Production in the New Generation of Apricot Cultivars: Self-incompatibility, S-RNase Allele Identification, and Incompatibility Group Assignment


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Identification of Self-Incompatibility Alleles by Specific PCR Analysis and S-RNase Sequencing in Apricot


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S-RNaseallele identification and incompatibility group assignment in apricot cultivars


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Chilling and Heat Requirements of Temperate Stone Fruit Trees (Prunus sp.)


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Determination of Self- and Inter-(in)compatibility Relationships in Apricot Combining Hand-Pollination, Microscopy and Genetic Analyses


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Pollination Management in Stone Fruit Crops


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Molecular characterization of genetic diversity in apricot cultivars: Current situation and future perspectives


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Male meiosis in sweet cherry is constrained by the chilling and forcing phases of dormancy


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Self-incompatibility in apricot: identifying pollination requirements to optimize fruit production


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Pollination requirements of new apricot (Prunus armeniaca L.) cultivars


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Male Meiosis as a Biomarker for Endo- to Ecodormancy Transition in Apricot


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Chilling Requirements of Apricot (Prunus armeniaca L.) Cultivars Using Male Meiosis as a Dormancy Biomarker


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Transcriptomic and Metabolomic Response to High Light in the Charophyte Alga Klebsormidium nitens


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Toxicity and bioconcentration of chlorpyrifos in aquatic organisms: Artemia parthenogenetica (Crustacea), Gambusia affinis, and Aphanius iberus (Pisces)


research line

BCR and TCR repertoire analysis


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Single-cell atlas of rainbow trout peripheral blood leukocytes and profiling of their early response to infectious pancreatic necrosis virus


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Teleost IgD+IgM- B Cells Mount Clonally Expanded and Mildly Mutated Intestinal IgD Responses in the Absence of Lymphoid Follicles


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Rainbow Trout IgM+ B Cells Preferentially Respond to Thymus-Independent Antigens but Are Activated by CD40L


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Passive Immunization Delays Disease Outcome in Gilthead Sea Bream Infected With Enteromyxum leei (Myxozoa), Despite the Moderate Changes in IgM and IgT Repertoire


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Insights Into the Evolution of the prdm1/Blimp1 Gene Family in Teleost Fish


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Diversity of Rainbow Trout Blood B Cells Revealed by Single Cell RNA Sequencing


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Pro-Inflammatory and B Cell Regulating Capacities of TWEAK in Rainbow Trout (Oncorhynchus mykiss)


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Individual B cells transcribe multiple rearranged immunoglobulin light chains in teleost fish


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Pleiotropic Role of Rainbow Trout CXCRs in Response to Disease and Environment: Insights from Transcriptional Signatures and Structure Analysis


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Teleost IgM+ plasma-like cells: beyond antibody secretion


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Computational learning of microRNA-based prediction of pouchitis outcome after restorative proctocolectomy in patients with ulcerative colitis


project

Mejora de las vacunas DNA frente a virus en acuicultura: análisis de la respuesta inmune protectiva no específica y específica en el modelo trucha / rabdovirus y modificación de las construcciones genéticas utilizadas hasta el momento.


project

Adjuvants and immunomodulators


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Personalized risk predictor for acute cellular rejection in lung transplant using soluble CD31

We evaluated the contribution of artificial intelligence in predicting the risk of acute cellular rejection...


project

Nuevas estrategias de vacunación DNA frente a virus en peces utilizando el modelo trucha arcoiris / rhabdovirus de la septicemia hemorrágica vírica (VHSV): búsqueda de adyuvantes moleculares entre moléculas implicadas en la respuesta inmune temprana


project

The Network of Animal Disease Infectiology Research Facilities (NADIR)


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A deep learning approach to evaluate intestinal fibrosis in magnetic resonance imaging models

Fibrosis may be introduced as a severe complication of inflammatory bowel disease (IBD). This is...


project

Papel inmunomodulador y microbicida de las quimioquinas en trucha arcoiris


project

Teleost B lymphocytes, the equivalent of mammalian B1 lymphocytes?


project

Targeted disease prophylaxis in European fish farming (Targetfish)


project

Advanced Tools and Research Strategies for Parasite Control in European farmed fish (ParaFishControl)


project

Papel inmune de las dendríticas CD8+ de teleosteos en enfermedad y vacunación


project

VetBioNet


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Plasma proteome dynamics of COVID-19 severity learnt by a graph convolutional network of multi-scale topology

Efforts to understand the molecular mechanisms of COVID-19 have led to the identification of ACE2...


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Deciphering the Dynamic Molecular Program of Radiation-Induced Endothelial Senescence

Radiation-induced cellular senescence is a double-edged sword, acting as both a tumor suppression process limiting tumor proliferation,...


project

Teleost mucosal B1-like lymphocytes at the crossroad of tolerance and immunity


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Deep models of integrated multiscale molecular data decipher the endothelial cell response to ionizing radiation

The vascular endothelium is a hot spot in the response to radiation therapy for both...


project

Búsqueda de adyuvantes efectivos para vacunación oral de peces


project

Relation between the microbiota, diet composition and response to vaccination in rainbow trout


project

Blocking BAFF signaling to treat proliferative kidney disease (PKD) in trout (PKDcontrol)


project

Green innovation strategies for animal health management: towards sustainable Aquaculture (GRINNAQUA)


project

European Partnership Animal health and Welfare


project

Respuestas IgM e IgD en mucosas de peces: cinética, interacciones, respuestas secundarias, memoria y quimiotaxis


research line

Optimize novel vaccination strategies for aquaculture


project

MMD-LLC

Modélisation multimodale et dynamique de l’évolution de la Leucémie Lymphoïde Chronique


research line

Understand how the adaptive immune system is regulated in teleost fish


research group

Machine Learning in Multi-Omics (MLiMO)

At MLiMO, we harness advanced machine learning and integrative multi-omics approaches to unravel the complexity...


orcid publication

Protein Profile and Simulated Digestive Behavior of Breast Milk from Overweight and Normal Weight Mothers


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Thermal stability of bovine lactoferrin prepared by cation exchange chromatography and its blends with authorized additives for infant formulas


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Peptidomic Characterization and Amino Acid Availability after Intake of Casein vs. a Casein Hydrolysate in a Pig Model


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Characterization of B Cell Responses in Rainbow Trout (Oncorhynchus Mykiss) Affected by Red Mark Syndrome


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Colonic MicroRNA Profiles, Identified by a Deep Learning Algorithm, That Predict Responses to Therapy of Patients With Acute Severe Ulcerative Colitis

We developed, DEEPCOL, an algorithm that identifies patients with ASUC who respond vs do not...


orcid publication

Male sex in houseflies is determined by Mdmd, a paralog of the generic splice factor gene CWC22

Across species, animals have diverse sex determination pathways, each consisting of a hierarchical cascade of...


research line

Translational Applications in the global LIfE area

Applying our findings to improve clinical outcomes and foster sustainable agricultural practices.


research line

Tumour/Virus/Bac Microenvironments

Investigating the dynamics of tumour/virus/bacteria–host interactions, focusing on immune modulation and spatial heterogeneity.


research line

Multi-omics Integration

Combining genomics, transcriptomics, proteomics, and spatial data to achieve a holistic view of biological systems.


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