• Research Topics

Found 4650 Results
Page 7 of 47

orcid publication

TDP-43 Pathology and Prionic Behavior in Human Cellular Models of Alzheimer’s Disease Patients

orcid publication

Multitarget Hybrid Fasudil Derivatives as a New Approach to the Potential Treatment of Amyotrophic Lateral Sclerosis

orcid publication

Targeting autophagy in disease: established and new strategies

orcid publication

Glycosylation of Epigallocatechin Gallate by Engineered Glycoside Hydrolases from Talaromyces amestolkiae: Potential Antiproliferative and Neuroprotective Effect of These Molecules

orcid publication

Network pharmacology reveals multitarget mechanism of action of drugs to be repurposed for COVID-19

orcid publication

New Statement about NRF2 in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia

orcid publication

The mechanism of macroautophagy: The movie

orcid publication

Discovery of Mitophagy Inhibitors with Therapeutic Potential in Different Familial Amyotrophic Lateral Sclerosis Mutations

orcid publication

The inhibition of NCS-1 binding to Ric8a rescues fragile X syndrome mice model phenotypes

orcid publication

The Dual PDE7-GSK3β Inhibitor, VP3.15, as Neuroprotective Disease-Modifying Treatment in a Model of Primary Progressive Multiple Sclerosis

orcid publication

Efficacy of Bromhexine versus Standard of Care in Reducing Viral Load in Patients with Mild-to-Moderate COVID-19 Disease Attended in Primary Care: A Randomized Open-Label Trial

orcid publication

Emerging clinical investigational drugs for the treatment of amyotrophic lateral sclerosis

orcid publication

Functional Characterization of a Familial ALS-Associated Missense TBK1 (p-Arg573Gly) Mutation in Patient-Derived Lymphoblasts

orcid publication

Progranulin Deficiency Induces Mitochondrial Dysfunction in Frontotemporal Lobar Degeneration with TDP-43 Inclusions

orcid publication

To Target or Not to Target Schistosoma mansoni Cyclic Nucleotide Phosphodiesterase 4A?

orcid publication

N'-Phenylacetohydrazide Derivatives as Potent Ebola Virus Entry Inhibitors with an Improved Pharmacokinetic Profile

orcid publication

The emerging role of mixed lineage kinase 3 (MLK3) and its potential as a target for neurodegenerative diseases therapies

orcid publication

Identification of a new structural family of SGK1 inhibitors as potential neuroprotective agents

orcid publication

Efficacy of a benzothiazole‐based LRRK2 inhibitor in oligodendrocyte precursor cells and in a murine model of multiple sclerosis

orcid publication

Discovery of Thiophene Derivatives as Potent, Orally Bioavailable, and Blood–Brain Barrier-Permeable Ebola Virus Entry Inhibitors

orcid publication

Proteome Aggregation in Cells Derived from Amyotrophic Lateral Sclerosis Patients for Personalized Drug Evaluation

orcid publication

Druggable cavities and allosteric modulators of the cell division cycle 7 (CDC7) kinase

orcid publication

TDP-43 Modulation for the Treatment of Neurodegenerative Diseases: Rationale and Assay Methodologies

orcid publication

RIPK1 expression and inhibition in tauopathies: implications for neuroinflammation and neuroprotection

orcid publication

11C-Labeling of a Flavanone Extracted from a South American Native Species for Evaluation of Its Interaction with GSK-3β

orcid publication

Discovery of Sphingosine-1-Phosphate Receptor Modulators as Potential CHI3L1 Inhibitors by Ligand-Based Virtual Screening and Molecular Dynamics Simulations

orcid publication

Discovery of a brain penetrant SGK1 inhibitor using a ligand- and structure-based virtual screening methodology

orcid publication

IgT and IgD dominance in the teleost central nervous system

orcid publication

Determination of thermal conductivity, specific heat and thermal diffusivity of albacore (Thunnus alalunga)

orcid publication

DEGRADATION KINETICS OF PROTEIN DIGESTIBILITY AND AVAILABLE LYSINE DURING THERMAL-PROCESSING OF TUNA

orcid publication

MATHEMATICAL-MODELING AND SIMULATION OF THE THERMAL-PROCESSING OF ANISOTROPIC AND NONHOMOGENEOUS CONDUCTION-HEATED CANNED FOODS - APPLICATION TO CANNED TUNA

orcid publication

Kinetics of thermal degradation of thiamine and surface colour in canned tuna

orcid publication

Optimal control of heat and mass transfer in food and bioproducts processing

orcid publication

OPTIMIZATION OF AIR-DRYING OF FOODS

orcid publication

ICRS/DS: A computer package for the optimization of batch processes and its applications in food processing

orcid publication

Different strategies for controlling pressure during the cooling stage in batch retorts

orcid publication

Computer aided design and optimization of sterilization of canned tuna

orcid publication

Time-temperature effects on microbial, chemical and sensory changes during cooling and aging of cheddar cheese

orcid publication

Global optimization of chemical processes using stochastic algorithms

orcid publication

Dynamic optimization of batch reactors using adaptive stochastic algorithms. (vol 36, pg 2256, 1997)

orcid publication

A complete dynamic model for the thermal processing of bioproducts in batch units and its application to controller design

orcid publication

Stochastic optimization for optimal and model-predictive control

orcid publication

Rebuttal to the comments of Rein Luus on "Dynamic optimization of batch reactors using adaptive stochastic algorithms"

orcid publication

Modeling and adaptive control for batch sterilization

orcid publication

Design of a class of stabilizing nonlinear state feedback controllers with bounded inputs

orcid publication

A hybrid method for the optimal control of chemical processes

orcid publication

Second-order sensitivities of general dynamic systems with application to optimal control problems

orcid publication

Temperature control in microwave combination ovens

orcid publication

Passive control design for distributed process systems: Theory and applications

orcid publication

Optimization of hybrid discrete/continuous dynamic systems

orcid publication

Numerical strategies for optimal experimental design for parameter identification of non-linear dynamic (Bio-)chemical processes

orcid publication

Efficient optimal control of bioprocesses using second-order information

orcid publication

Optimal control of distributed processes using reduced order models

orcid publication

On the optimal control of contact-cooking processes

orcid publication

Integrated process design and control via global optimization: A wastewater treatment plant case study

orcid publication

Robust nonlinear control design of distributed process systems with input constraints

orcid publication

Restricted second order information for the solution of optimal control problems using control vector parameterization

orcid publication

Optimal sensor location and reduced order observer design for distributed process systems

orcid publication

From irreversible thermodynamics to a robust control theory for distributed process systems

orcid publication

Computation of optimal identification experiments for nonlinear dynamic process models: a stochastic global optimization approach

orcid publication

A COMBINED ELECTROMAGNETIC AND HEAT TRANSFER MODEL FOR HEATING OF FOODS IN MICROWAVE COMBINATION OVENS

orcid publication

Parameter estimation in biochemical pathways: A comparison of global optimization methods

orcid publication

Integrated Nonlinear Optimization of Bioprocesses via Linear Programming

orcid publication

Improving food processing using modern optimization methods

orcid publication

Global optimization of climate control problems using evolutionary and stochastic algorithms

orcid publication

Global optimization of bioprocesses using stochastic and hybrid methods

orcid publication

Dynamic optimization of double-sided cooking of meat patties

orcid publication

Solving nonconvex climate control problems: Pitfalls and algorithm performances

orcid publication

Reduced-order models for nonlinear distributed process systems and their application in dynamic optimization

orcid publication

On systematic model reduction techniques for dynamic optimization and robust control of distributed process systems

orcid publication

Multi-objective optimization for the design of bio-processes

orcid publication

Energy and society

orcid publication

Dynamic optimization of distributed parameter systems using second-order directional derivatives

orcid publication

Dissipative systems: From physics to robust nonlinear control

orcid publication

Chapter D4 Multi-objective integrated design and control using stochastic global optimization methods

orcid publication

A model-based approach to develop periodic thermal treatments for surface decontamination of strawberries

orcid publication

State reconstruction in spatially distributed BioProcess systems using reduced order models: Application to the gluconic acid production

orcid publication

Robust parameter estimation in nonlinear dynamic process models

orcid publication

Global optimization for integrated design and control of computationally expensive process models

orcid publication

Dynamic optimization of single- and multi-stage systems using a hybrid Stochastic-deterministic method

orcid publication

Dynamic optimization of complex distributed process systems

orcid publication

Dynamic optimization of bioprocesses: Efficient and robust numerical strategies

orcid publication

An efficient real-time dynamic optimization architecture for the control of non-isothermal tubular reactors

orcid publication

A systematic approach to plant-wide control based on thermodynamics

orcid publication

A software toolbox for the dynamic optimization of nonlinear processes

orcid publication

A hybrid approach for efficient and robust parameter estimation in biochemical pathways

orcid publication

Stabilization of inhomogeneous patterns in a diffusion-reaction system under structural and parametric uncertainties

orcid publication

Robust parameter estimation in a model for glucose kinetics in type 1 diabetes subjects

orcid publication

Novel metaheuristic for parameter estimation in nonlinear dynamic biological systems

orcid publication

Model based optimization of biochemical systems using multiple objectives: A comparison of several solution strategies

orcid publication

Improved optimization methods for the multiobjective design of bioprocesses

orcid publication

Dynamic optimization of a simulated moving bed (SMB) chromatographic separation process

orcid publication

Computing optimal operating policies for the food industry

orcid publication

A thermodynamic based plant-wide control design procedure of the tennessee eastman process

orcid publication

Welcome and introduction

orcid publication

Scatter search for chemical and bio-process optimization

orcid publication

Robust feed-back control of distributed chemical reaction systems

orcid publication

Power-law models of signal transduction pathways

orcid publication

Optimal field reconstruction of distributed process systems from partial measurements

orcid publication

Optimal dynamic experimental design in systems biology: Applications in cell signaling

Page 7 of 47
Computational Biology and Bioinformatics (BCB)

CONTACT | LEGAL NOTICE | COOKIES POLICY | DATA PROTECTION

© CSIC - Consejo Superior de Investigaciones Científicas. 2026 - All rights reserved. Powered by Scienseed
Go to Top