Page 1 of 1
research line
Transcriptomics
research line
Metabolomics
research line
Antiviral therapies
research line
Neuroinflammation
research line
Virology
research line
Outreach for bioinformatics reserach
We develop actions and materials to bring the bioinformatics discipline to children, schools, and the...
research line
Modeling intereactions in biological systems
research line
Modeling microbial systems at multiple scales
research line
Development of Genomic tools for Population Analysis of Variability
Statistical Studies to develop methods to better understand the genetic variability. Development of Software and...
research line
omics analysis of male reproductive traits in swine
Applying different omics approaches (GWAS, WGS, RNA-Seq, MNase-Seq, single cell multiome – RNA + ATAC)...
research line
Productive efficiency and resilience of Spanish chicken breeds to global warming
This project proposes the sequencing of up to 600 hens of Spanish breeds. With this...
research line
Increase the depth of tumor spatial phenotyping with virtual multiplexing
Single-cell resolution volumetric imaging is an uprising technique in the biomedical research as it permits...
research line
Unravelling the role of the tumor microenvironment in tumor invasive behavior and resistance to immunotherapy in Diffuse Midline Glioma.
Modern technologies allow to study the distinct aspects involved in tumor progression from different angles,...
research line
Understanding the mode-of-action of T cell immunotherapy against solid tumors to overcome resistance.
Despite the revolutionary success of cancer T-Cell Immunotherapies their efficacy in treating solid tumours, is...
research line
New methods to elucidate molecular effects of mutations on protein structure and function
This research line is conducted in collaboration with Uppsala University, where I co-supervise a PhD...
research line
Dynamics and optimal control of biosystems
research line
Optimality principles in biological systems
research line
Predictive models for precision modulation of G protein–coupled receptors (GPCRs): allosteric modulators and biassed agonists
Starting from our deep understanding of the GPCR signaling systems, and our current structure-based computational...
research line
Development of novel polypharmacology-based cancer immunotherapy strategies targeting the purinergic signalling pathway
Blocking the A2B Adenosine Receptor is a selective mechanism of therapeutic intervention, since this receptor...
research line
Developing a DNA biofoundry towards the AI-guided exploration of microbial chemical space.
We are actively involved in the development of a DNA biofoundry (CNBio) that integrates advanced...
research line
System level analysis and designing microbial communities
The division of labor allows an expanded complexity and functionality in microorganisms. Guided by these...
research line
Understanding and exploiting the multioptimality of microbial metabolism
Microbial metabolism operates and evolves under the trade-off between two principles: optimality under one given...
research line
Increasing the completeness and scope of metabolic reconstructions
We are committed to building a niche-specific collection of standardised and highly reproducible metabolic models....
research line
BCR and TCR repertoire analysis
research line
Optimize novel vaccination strategies for aquaculture
research line
Translational Applications in the global LIfE area
Applying our findings to improve clinical outcomes and foster sustainable agricultural practices.
research line
Tumour/Virus/Bac Microenvironments
Investigating the dynamics of tumour/virus/bacteria–host interactions, focusing on immune modulation and spatial heterogeneity.
research line
Multi-omics Integration
Combining genomics, transcriptomics, proteomics, and spatial data to achieve a holistic view of biological systems.
research line
Machine Learning & Deep Learning in Biology
Developing and applying cutting-edge algorithms for biological data analysis and predictive modelling.
research line
Diet-host-microbe interactions in health and disease
research line
Topological Machine Learning
Exploring topological and geometric approaches to unveil robust patterns in high-dimensional multi-omics data.
research line
OMICS TECHNOLOGIES AND NEW COMPUTATIONAL CHALLENGES
In recent years, omics technologies have become common practice in the field of neuroscience. Multiple...
research line
Crop Genomics and Breeding Methods
research line
Digital evolution
Studying evolution in the lab provides valuable insights but is often constrained by long timescales...
research line
Development of efficient methods for calculating paths of minimum or maximum parameter values (e.g., minimum energy paths) through surfaces of any number of dimensions.
MEPSAnd: Minimum Energy Path Surface Analysis over n-dimensional surfaces [http://bioweb.cbm.uam.es/software/MEPSAnd/] MEPSA: Minimum Energy Pathway A...
research line
Promoting citizen science to bridge scientific research and society through participatory and educational initiatives
We are committed to training the next generation of interdisciplinary experts who integrate data science,...
research line
Investigating host–microbiota interactions in complex diseases through systems biology, network analysis, and advanced in vitro models
We employ systems biology approaches and complex network analysis to elucidate host–microbiota interactions in chronic...
research line
Understanding human metabolic variability through computational and bioinformatic methods for precision nutrition
We develop and apply computational and bioinformatic tools to investigate how different nutrients, nutritional strategies,...
research line
Interacciones hospedador-microbiota
Investigar las interacciones hospedador-microbiota en enfermedades complejas, con el objetivo de incluirlo en las intervenciones...
research line
Intracellular trafficking of vesicles in hyperpolarized cells
Using a filamentous fungus as the model organism, we identify and characterize common eukaryotic and...
research line
The regulatory genome of human malaria mosquitoes
A malaria infection induces drastic and rapid phenotypic and gene expression changes in mosquitoes that...
research line
Transcriptional regulation in human malaria parasites
Over the last years we have started to decipher how different Plasmodium spp. regulate their genome...
research line
Epigenetics of adaptation in malaria
We are interested in understanding the epigenetic mechanisms that control cell plasticity in pathogens in response...
research line
Metagenomics for the study of toxigenic fungi
Given the growing importance of omics and their potential for ecological studies, we are starting...
research line
Pangenomics and transcriptional regulation of grasses
research line
Transcript divergence in aging and disease
research line
Long-reads multiomics data analysis
research line
Statistial methods for multi-omics integration
research line
Protein Language Models
We use language models for functional annotation of uncharacterised proteins.
research line
Protein multifunction
We focus on the understanding and characterization of multi-functional behaviour of proteins.
research line
Bridging the resolution gap with hybrid methods
We develop and apply new hybrid methods for combining multiresolution structural information in collaboration with...
research line
Multiscale dynamics of macromolecular biomachines
We address the study and simulation of the dynamics of large biomolecular systems Normal-Mode Analysis...
research line
Protein Modelling
We develop tools for modeling protein structures and their interactions. This includes novel methods for...
Page 1 of 1