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Page 4 of 46

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A 1 H and 13 c Nmr study of the structure and tautomerism of 4-pyrazolylpyrazolinones

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Synthesis and NMR spectroscopy ( 1 H 13 C) of 1-(2′-benzothiazolyl)-3(5),4-polymethylenepyrazoles and related compounds

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SYNTHESIS OF PSI-[CH(CN)NH] PSEUDOPEPTIDES - A NEW PEPTIDE-BOND SURROGATE

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LIPASE-MEDIATED ACYLATION OF ACYCLONUCLEOSIDES - APPLICATION TO NOVEL FLUOROQUINOLONE DERIVATIVES

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TAUTOMERISM AND ACIDITY IN 4-QUINOLONE-3-CARBOXYLIC ACID-DERIVATIVES

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(E)-1-ALKYL-[2-(1H-AZOL-2-YL)VINYL]PYRIDINIUM SALTS - THEORETICAL-ANALYSIS, SYNTHESIS AND EVALUATION OF THEIR INTERACTION WITH CHOLINE-ACETYLTRANSFERASE

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THE PROBLEM OF THE EXISTENCE OF C(AR)-H...N INTRAMOLECULAR HYDROGEN-BONDS IN A FAMILY OF 9-AZAPHENYL-9H-CARBAZOLES

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THE MOLECULAR-STRUCTURE OF 3(5)-METHYL-4,5(3)-TRIMETHYLENEPYRAZOLE HYDROCHLORIDE AND ITS C-13 AND N-15 NMR-SPECTROSCOPY

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SYNTHESIS AND BIOLOGICAL EVALUATION OF 4-QUINOLONE RIBOSIDES

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SO2 EXTRUSION IN 1,2,6-THIADIAZINE 1,1-DIOXIDES - A NOVEL SYNTHESIS OF PYRAZOLES

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TAUTOMERISM OF BENZOPENTA AND CYCLOPENTA-[1,2,6]THIADIAZINE S,S-DIOXIDES

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REGIOSELECTIVE LIPASE-MEDIATED ACYLATION-DEACYLATION IN THIADIAZINE DIACYCLONUCLEOSIDES

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The structure of the compounds resulting from the reaction of arylhydrazines with dehydroacetic acid: an NMR and crystallographic study

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The Regio- and Stereocontrolled Ring Opening of Heteroarylglycidates with Nitrogen Nucleophiles

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Semiempirical (AM1, PM3 and SAM1) calculations of the protonation enthalpies of proton sponges related to 1,8-diaminonaphthalene. Estimation of the aqueous basicity of new designed superbases

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Regioselective Mucor miehei lipase catalyzed synthesis of podands containing a 1,3-bis(1H-Pyrazol-1-yl)propane unit

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New 1,2,6-thiadiazine dioxide acyclonucleosides: synthesis and antiviral evaluation

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Dioxides of bicyclic thiadiazines: a new family of smooth muscle relaxants

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New Synthetic Route to of 1,2,4-Thiadiazolines and 1,3-Thiazolines via Thiadiazolopyridinium Salts

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Conformation and ortho steric effects in a series of 2-(pyrazol-1-yl)quinolines

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Synthesis and antiviral activity of modified 1,2,6-thiadiazine dioxide acyclonucleosides

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Selective carriers of norepinephrine and ammonium ions: ionophoric properties and molecular modelling studies of diester crown compounds containing a 1,3-bis(1H-pyrazol-1-yl)propane unit

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Regioselective lipase-catalyzed synthesis of l-glutamic α-monoamide derivatives. Effect of the N-blocking group

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Regioselective lipase catalyzed synthesis of diester crowns. New asymmetric macrocycles containing a 1,3-bis(1H-pyrazol-1-yl)propane unit

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Molecular modeling of (E)-1-Alkyl-4(3)-[2-(1H-azolyl)vinyl]-pyridinium salts and evaluation of their behavior towards choline acetyltransferase

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Comparative molecular field analysis (CoMFA) on [6]+[6] fused pyrazines with nematocide properties

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Benzothiadiazine dioxide acyclonucleosides as lead compounds for the development of new agents against human cytomegalovirus and varicella-zoster virus infections

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Arylimino-1,2,4-thiadiazolidinones: A new family of potassium channel openers

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Applications of a statistical model to the analysis of the kinetic parameters in isothermal and non-isothermal crystallization of polymer blends based on PVDF

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Base promoted transformation on thiadiazolopyridinium chlorides

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Towards lipophilic derivatives of S-adenosyl-L-methionine

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Synthesis of nonsymmetrically 3,4-disubstituted 1,2,5-thiadiazole dioxides

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Resolution of 1-(4-amino-3-chloro-5-cyanophenyl)-2-bromo-1-ethanol by lipase mediated enantioselective alcoholysis, hydrolysis and acylation

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Phosphodiesterase inhibitory properties of losartan. Design and synthesis of new lead compounds

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Lipase catalysed amidation of diethyl glutamate derivatives: peculiarities of ethyl S- and R-pyroglutamate

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Enzymatic alcoholysis of SO2-uracil analog diacyclonucleosides. Long-distance effect of the substituents on the regioselectivity

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Selective dopamine receptors: Synthesis, complexing properties, and molecular modelling studies of new podands derived from 4-hydroxy-1H-pyrazole

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On the tautomerism of 2,1,3-benzothiadiazinone S,S-dioxide and related compounds

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Novel potential agents for human cytomegalovirus infection: Synthesis and antiviral activity evaluation of benzothiadiazine dioxide acyclonucleosides

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Intramolecular oxidative cyclizations in heteroarylthioureas: A versatile pathway to bridgehead heterocyclic systems

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Imidazothiadiazine dioxides: Synthesis and antiviral activity

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Chlorophenylmethyl benzothiadiazine dioxides derivatives: potent human cytomegalovirus inhibitors

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Candida antarctica lipase B catalysed amidation of pyroglutamic acid derivatives. A reaction survey

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Thienothiadiazine 2,2-Dioxide Acyclonucleosides: Synthesis and Antiviral Activity

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Regioselective lipase-catalysed gamma-monoamidation of D-glutamic acid diesters: effect of the N-protecting group

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Novel agents for the treatment of human cytomegalovirus infection

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Nonnucleoside human cytomegalovirus inhibitors: Synthesis and antiviral evaluation of (chlorophenylmethyl)benzothiadiazine dioxide derivatives

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N-benzylpiperidine derivatives of 1,2,4-thiadiazolidinone as new acetylcholinesterase inhibitors

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Lipase-catalysed synthesis of new acetylcholinesterase inhibitors: N-benzylpiperidine aminoacid derivatives

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Hindered inversion/rotation in diheteroaryl alkyl amines with a N-(1-pyrazolyl) group: Dynamic NMR and molecular modelling studies

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Benzyl derivatives of 2,1,3-benzo- and benzothieno[3,2-a]thiadiazine 2,2-dioxides: First phosphodiesterase 7 inhibitors

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Benzothiadiazine dioxide dibenzyl derivatives as potent human cytomegalovirus inhibitors: Synthesis and comparative molecular field analysis

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Inhibition of tau phosphorylation: a new therapeutic strategy for the treatment of Alzheimer's disease and other neurodegenerative disorders

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Recent strategies in the development of new human cytomegalovirus inhibitors

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Peripheral and Dual Binding Site Acetylcholinesterase Inhibitors: Implications in treatment of Alzheimer's Disease

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O-Pyrazolylpropynyl-Hydroxylamines as Versatile Intermediates in the Synthesis of Compounds of Pharmacological Interest

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CoMFA of benzyl derivatives of 2,1,3-benzo and benzothieno[3,2-a]thiadiazine 2,2-dioxides: clues for the design of phosphodiesterase 7 inhibitors

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Anti-HIV-1 Activity of Benzothiadiazine Dioxide

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Non-Cholinergic Pharmacotherapy Approaches to the Future Treatment of Alzheimer's Disease

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Inhibitors of glycogen synthase kinase-3: future therapy for unmet medical needs?

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Glycogen synthase kinase 3 (GSK-3) inhibitors as new promising drugs for diabetes, neurodegeneration, cancer, and inflammation

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First non-ATP competitive glycogen synthase kinase 3 beta (GSK-3 beta) inhibitors: Thiadiazolidinones (TDZD) as potential drugs for the treatment of Alzheimer's disease

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An experimental NMR and semi-empirical theoretical study of the conformation of styrylchromones and styryl alkyl or aryl ketones (benzylidene ketones)

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APPLICATION OF ULTRASONIC NEBULIZATION FOR THE DETERMINATION OF RARE-EARTH ELEMENTS IN PHOSPHATES AND RELATED SEDIMENTARY-ROCKS USING INDUCTIVELY-COUPLED PLASMA-ATOMIC EMISSION-SPECTROMETRY WITH COMMENTS ON DISSOLUTION PROCEDURES

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Thienyl and phenyl alpha-halomethyl ketones: New inhibitors of glycogen synthase kinase (GSK-3 beta) from a library of compound searching

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Synthesis and muscarinic activities of O-[benzyl- or benzoylpyrazolyl)propynyl]-oximes of N-methylpiperidinone, 3-tropinone, and 3-quinuclidinone

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Benzothiadiazine dioxides (BTD) derivatives as non-nucleoside human cytomegalovirus (HCMV) inhibitors. Study of structural requirements for biological activity

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AMPA glutamate receptors and neuropathic pain.

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Nitric oxide in the cerebral cortex of amyloid-precursor protein (SW) Tg2576 transgenic mice

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GSK-3 inhibitors: Discoveries and developments

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CODES/Neural network model: a useful tool for in silico prediction of oral absorption and blood-brain barrier permeability of structurally diverse drugs

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SAR and 3D-QSAR studies on thiadiazolidinone derivatives: Exploration of structural requirements for glycogen synthase kinase 3 inhibitors

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Regulation of inflammatory response in neural cells in vitro by thiadiazolidinones derivatives through peroxisome proliferator-activated receptor gamma activation

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Molecular mechanics description of cytosine energy and geometry using preliminary ab initio results

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Marine compounds for the therapeutic treatment of neurological disorders

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Good oral absorption prediction on non-nucleoside benzothiadiazine dioxide human cytomegalovirus inhibitors using combined chromatographic and neuronal network techniques

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Design, synthesis, and biological evaluation of dual binding site acetylcholinesterase inhibitors: New disease-modifying agents for Alzheimer's disease

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Design and synthesis of N-benzylpiperidine-purine derivatives as new dual inhibitors of acetyl- and butyryleholinesterase

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Cyclic nucleotide phosphodiesterases and their role in immunomodulatory responses: Advances in the development of specific phosphodiesterase inhibitors

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Donepezil-tacrine hybrid related derivatives as new dual binding site inhibitors of AChE

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Targeting beta-amyloid pathogenesis through acetylcholinesterase inhibitors

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Novel cholinesterase inhibitors as future effective drugs for the treatment of Alzheimer's disease

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Marine Compounds as a New Source for Glycogen Synthase Kinase 3 Inhibitors

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Manzamine B and E and ircinal A related alkaloids from an Indonesian Acanthostrongylophora sponge and their activity against infectious, tropical parasitic, and Alzheimer's diseases

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Enantioselective LC/MS method for the determination of an antimalarial agent fenozan B07 in dog plasma

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S4-04-06

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NP031112, a thiadiazolidinone compound, prevents inflammation and neurodegeneration under excitotoxic conditions: Potential therapeutic role in brain disorders

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Glycogen synthase kinase-3 (GSK-3) inhibitory activity and structure-activity relationship (SAR) studies of the manzamine alkaloids. Potential for Alzheimer's disease

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Preclinical efficacy on GSK-3 inhibitors: Towards a future generation of powerful drugs

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Potent beta-amyloid modulators

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PDE7 inhibitors as new drugs for neurological and inflammatory disorders

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Non-ATP competitive glycogen synthase kinase 3 beta (GSK-3 beta) inhibitors: Study of structural requirements for thiadiazolidinone derivatives

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Neuroprotective effect of the new thiadiazolidinone NP00111 against oxygen-glucose deprivation in rat hippocampal slices: Implication of ERK1/2 and PPAR gamma receptors

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GSK-3 inhibitors: A ray of hope for the treatment of Alzheimer's disease?

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CODES, a novel procedure for ligand-based virtual screening: PDE7 inhibitors as an application example

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Antidepressant-like effect of the novel thiadiazolidinone NP031115 in mice

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S4-02-03: TDZDS: Can we target tau, beta-amyloid and neurodegeneration simultaneously?

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Thienylhalomethylketones: Irreversible glycogen synthase kinase 3 inhibitors as useful pharmacological tools

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The first enantioselective synthesis of palinurin

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Tacrine-Melatonin Hybrids as Multifunctional Agents for Alzheimer's Disease, with Cholinergic, Antioxidant, and Neuroprotective Properties

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Computational Biology and Bioinformatics (BCB)

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